Right parietal hypoactivation in a cocaine-dependent group during a verbal working memory task
Impacto
Scholar |
Otros documentos de la autoría: Bustamante, Juan Carlos; Barrós-Loscertales, Alfonso; Ventura Campos, Mercedes; Sanjuán Tomás, Ana; Llopis Llácer, Juan José; Parcet, Maria Antònia; Avila, Cesar
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/8033
comunitat-uji-handle3:10234/8636
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http://dx.doi.org/10.1016/j.brainres.2010.12.042 |
Metadatos
Título
Right parietal hypoactivation in a cocaine-dependent group during a verbal working memory taskAutoría
Fecha de publicación
2011-02-23Editor
ElsevierISSN
0006-8993Cita bibliográfica
Brain Research (23 Febr. 2011), vol. 1375, p. 111-1119Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://www.sciencedirect.com/science/article/pii/S0006899310027071Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
It has been suggested that cocaine addiction affects the engagement of the frontoparietal networks in executive functions, such as attention and workingmemory. Thus, our objective was to investigate brain differences ... [+]
It has been suggested that cocaine addiction affects the engagement of the frontoparietal networks in executive functions, such as attention and workingmemory. Thus, our objective was to investigate brain differences between cocaine-dependent subjects and healthy controls during the performance ofaverbalworkingmemorytask. Nineteen comparison men and nineteen cocaine-dependent men performed a 2-back task. Data were acquired on a 1.5-T Siemens Avanto. Image processing and statistical analyses were carried out using SPM5; Biological Parametric Mapping (BPM) was used for further morphometric and correlation analyses. No performance differences were found between groups. However, the dorsal part of the right inferior parietal cortex (BA 40) was less activated in thecocaine-dependentgroup. Cocaine patients did not overactive any brain area when compared with controls. Our results show reduced activation in the brain areas related to the attention system incocaine-dependent men while performing averbalworkingmemorytask. Chronic cocaine use may affect the attentional system in the rightparietal lobe, making patients more prone to attentional deficits. [-]
Derechos de acceso
© 2010 Elsevier Inc. All rights reserved
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info:eu-repo/semantics/restrictedAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/restrictedAccess
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