• openAccess   A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women 

      Pastor, Antoni; Fernández Aranda, Fernando; Fitó, Montserrat; Jiménez-Murcia, Susana; Botella, Cristina; Fernández-Real, José Manuel; Frühbeck, Gema; Tinahones Madueño, Francisco Javier; Fagundo, Ana B.; Rodriguez, Joan; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; De la Torre, Rafael Public Library of Science (2016-02)
      The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ...
    • openAccess   An increase in visceral fat is associated with a decrease in the taste and olfactory capacity 

      Fernández García, José Carlos; Alcaide Torres, Juan; Santiago-Fernández, Concepción; Roca-Rodriguez, M.M.; Agüera, Zaida; Baños, Rosa Maria; Botella, Cristina; De la Torre, Rafael; Fernández-Real, José Manuel; Fruhbeck, Gema; Gómez Ambrosi, Javier; Jiménez-Murcia, Susana; Menchon, José Manuel; Casanueva, Felipe F.; Fernández Aranda, Fernando; Tinahones Madueño, Francisco Javier; Garrido-Sánchez, Lourdes Public Library of Science (2017)
      Introduction Sensory factors may play an important role in the determination of appetite and food choices. Also, some adipokines may alter or predict the perception and pleasantness of specific odors. We aimed to analyze ...
    • openAccess   Changes in Body Composition in Anorexia Nervosa: Predictors of Recovery and Treatment Outcome 

      Agüera, Zaida; Romero, Xandra; Arcelus, Jon; Sánchez, Isabel; Riesco, Nadine; Jiménez-Murcia, Susana; González Gómez, Jana; Granero, Roser; Custal, Nuria; Montserrat-Gil de Bernabé, Mónica; Tárrega, Salomé; Baños, Rosa Maria; Botella, Cristina; De la Torre, Rafael; Fernández García, José Carlos; Fernández-Real, José Manuel; Frühbeck, Gema; Gómez Ambrosi, Javier; Tinahones Madueño, Francisco Javier; Crujeiras, Ana B.; Casanueva, Felipe F.; Menchón, José Manuel; Fernández Aranda, Fernando Public Library of Science (2015)
      The restoration of body composition (BC) parameters is considered to be one of the most important goals in the treatment of patients with anorexia nervosa (AN). However, little is known about differences between AN diagnostic ...
    • closedAccess   Co-occurrence of non-suicidal self-injury and impulsivity in extreme weight conditions 

      Claes, Laurence; Fernández Aranda, Fernando; Jiménez-Murcia, Susana; Botella, Cristina; Casanueva, Felipe F.; De la Torre, Rafael; Fernández-Real, José Manuel; Frühbeck, Gema; Tinahones Madueño, Francisco Javier; Vilarrasa, Nuria; Montserrat-Gil de Bernabé, Mónica; Granero, Roser; Agüera, Zaida; Sancho, Carolina; Muehlenkamp, Jennifer; Menchón, José Manuel Elsevier (2013)
      The aims of the present study were to determine the prevalence of non-suicidal self-injury (NSSI) in different eating disorder (ED) groups and morbid obesity, and to investigate whether NSSI in different ED/obesity groups ...
    • openAccess   Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders? 

      Mallorquí Bagué, Núria; Fagundo, Ana B.; Jiménez-Murcia, Susana; De la Torre, Rafael; Baños, Rosa Maria; Botella, Cristina; Casanueva, Felipe F.; Crujeiras, Ana B.; Fernández García, José Carlos; Fernández-Real, José Manuel; Frühbeck, Gema; Granero, Roser; Rodríguez, Amaia; Tolosa-Sola, Iris; Ortega, Francisco J.; Tinahones Madueño, Francisco Javier; Álvarez Moya, Eva; Ochoa, Cristian; Menchón, José Manuel; Fernández Aranda, Fernando PLOS (2016-09-30)
      Introduction Addictions are associated with decision making impairments. The present study explores decision making in Substance use disorder (SUD), Gambling disorder (GD) and Obesity (OB) when a ...
    • openAccess   Executive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity 

      Fagundo, Ana B.; De la Torre, Rafael; Jiménez-Murcia, Susana; Agüera, Zaida; Granero, Roser; Tárrega, Salomé; Botella, Cristina; Baños, Rosa Maria; Fernández-Real, José Manuel; Rodríguez, Roser; Forcano, Laura; Frühbeck, Gema; Gómez Ambrosi, Javier; Tinahones Madueño, Francisco Javier; Fernández García, José Carlos; Casanueva, Felipe F.; Fernández Aranda, Fernando Public Library of Science (2012)
      Background: Extreme weight conditions (EWC) groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, ...
    • closedAccess   In vivo transcriptomic profile after a Mediterranean diet in high–cardiovascular risk patients: a randomized controlled trial 

      Castañer, Olga; Corella, Dolores; Covas Planells, María Isabel; Subirana, Isaac; Flores Mateo, Gemma; Nonell, Lara; Bulló, Mònica; De la Torre, Rafael; Portolés, Olga; Fitó, Montserrat American Society for Nutrition (2013)
      Background: Nutrients can exert healthy effects through nutrigenomic modulation. Data are scarce concerning the in vivo effect of a sustained traditional Mediterranean diet (TMD) pattern on the whole transcriptomic ...
    • closedAccess   Interaction Between Orexin-A and Sleep Quality in Females in Extreme Weight Conditions 

      Sauchelli, Sarah; Jiménez-Murcia, Susana; Fernández García, José Carlos; Garrido-Sánchez, Lourdes; Tinahones Madueño, Francisco Javier; Casanueva, Felipe F.; Baños, Rosa Maria; Botella, Cristina; Crujeiras, Ana B.; De la Torre, Rafael; Fernández-Real, José Manuel; Frühbeck, Gema; Granero, Roser; Ortega, Francisco J.; Rodríguez, Amaia; Zipfel, Stephan; Griel, Katrin E.; Menchón, José Manuel; Fernández Aranda, Fernando Wiley (2016-10-26)
      The current study examined the relationship between plasma orexin-A and sleep in obesity. Concentrations of orex in-A and sleep were evaluated in 26 obese, 40 morbid obe se and 32 healthy-weight participants. The sleep ...
    • closedAccess   Lifetime obesity in patients with eating disorders : increasing prevalence, clinical and personality correlates 

      Villarejo, Cynthia; Fernández Aranda, Fernando; Jiménez-Murcia, Susana; Peñas-Lledó, Eva; Granero, Roser; Panelo, Eva; Tinahones Madueño, Francisco Javier; Sancho, Carolina; Vilarrasa, Nuria; Montserrat-Gil de Bernabé, Mónica; Casanueva, Felipe F.; Fernández-Real, José Manuel; Frühbeck, Gema; De la Torre, Rafael; Treasure, Janet; Botella, Cristina; Menchón, José Manuel Wiley (2012)
      Objectives: The aims of our study were to examine the lifetime prevalence of obesity rate in eating disorders (ED) subtypes and to examine whether there have been temporal changes among the last 10 years and to explore ...
    • closedAccess   Loss of Control over Eating: A Description of the Eating Disorder/Obesity Spectrum in Women 

      Villarejo, Cynthia; Jiménez-Murcia, Susana; Alvárez Moya, Eva; Granero, Roser; Penelo, Eva; Treasure, Janet; Vilarrasa, Nuria; Gil Montserrat de Bernabé, Mónica; Casanueva, Felipe F.; Tinahones Madueño, Francisco Javier; Fernández-Real, José Manuel; Frühbeck, Gema; De la Torre, Rafael; Botella, Cristina; Agüera, Zaida; Menchón, José Manuel; Fernández Aranda, Fernando Wiley Online Library (2014)
      Goals This study aimed to analyse the association, commonalities and differences between obesity and eating disorders (ED). Method A total of 150 female patients [50 obese with bulimia nervosa (OB + BN), 50 obese with ...
    • openAccess   Mass Spectrometric Evaluation of Mephedrone In Vivo Human Metabolism: Identification of Phase I and Phase II Metabolites, Including a Novel Succinyl Conjugate 

      Pozo, Óscar J.; Ibáñez, Maria; Sancho, Juan V; Lahoz-Beneytez, Julio; Farré, Magi; Papaseit, Esther; De la Torre, Rafael; Hernandez, Felix American Society for Pharmacology and Experimental Therapeutics (ASPET) (2015-02)
      In recent years, many new designer drugs have emerged, including the group of cathinone derivatives. One frequently occurring drug is mephedrone; although mephedrone was originally considered as a “legal high” product, it ...
    • openAccess   Moderate-Vigorous Physical Activity across Body Mass Index in Females: Moderating Effect of Endocannabinoids and Temperament 

      Fernández Aranda, Fernando; Sauchelli, Sarah; Pastor, Antoni; González, Marcela L.; De la Torre, Rafael; Granero, Roser; Jiménez-Murcia, Susana; Baños, Rosa Maria; Botella, Cristina; Fernández-Real, José Manuel; Fernández García, José Carlos; Frühbeck, Gema; Gómez Ambrosi, Javier; Rodríguez, Roser; Tinahones Madueño, Francisco Javier; Arcelus, Jon; Fagundo, Ana B.; Agüera, Zaida; Miró, Jordi; Casanueva, Felipe F. Public Library of Science (2014)
      Background: Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional ...
    • openAccess   Modulation of higher-order olfaction components on executive functions in humans 

      Fagundo, Ana B.; Jiménez-Murcia, Susana; Giner-Bartolomé, Cristina; Islam, Mohamed A.; De la Torre, Rafael; Pastor, Antoni; Casanueva, Felipe F.; Crujeiras, Ana B.; Granero, Roser; Baños, Rosa Maria; Botella, Cristina; Fernández-Real, José Manuel; Frühbeck, Gema; Gómez Ambrosi, Javier; Menchón, José Manuel; Tinahones Madueño, Francisco Javier; Fernández Aranda, Fernando Public Library of Science (2015)
      The prefrontal (PFC) and orbitofrontal cortex (OFC) appear to be associated with both executive functions and olfaction. However, there is little data relating olfactory processing and executive functions in humans. The ...
    • openAccess   Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Human. 

      Fagundo, Ana B.; De la Torre, Rafael; Jiménez-Murcia, Susana; Agüera, Zaida; Pastor, Antoni; Casanueva, Felipe F.; Granero, Roser; Baños, Rosa Maria; Botella, Cristina; Pino Gutiérrez, Amparo del; Fernández-Real, José Manuel; Fernández García, José Carlos; Frühbeck, Gema; Gómez Ambrosi, Javier; Menchón, José Manuel; Moragrega Vergara, Inés; Rodríguez, Roser; Tárrega, Salomé; Tinahones Madueño, Francisco Javier; Fernández Aranda, Fernando Public Library of Science (2013)
      Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) ...
    • closedAccess   Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome 

      Sauchelli, Sarah; Jiménez-Murcia, Susana; Sánchez, Isabel; Riesco, Nadine; Custal, Nuria; Fernández García, José Carlos; Garrido-Sánchez, Lourdes; Tinahones Madueño, Francisco Javier; Steiger, Howard; Israel, Mimi; Baños, Rosa Maria; Botella, Cristina; De la Torre, Rafael; Fernández-Real, José Manuel; Ortega, Francisco J.; Frühbeck, Gema; Granero, Roser; Tárrega, Salomé; Crujeiras, Ana B.; Rodríguez, Amaia; Estivill, Xavier; Beckmann, Jacques S.; Casanueva, Felipe F. Elsevier (2016)
      Background and aims Orexins/hypocretins are orexigenic peptides implicated in the regulation of feeding behavior and the sleep/wake cycle. Little is known about the functioning of these peptides in anorexia nervosa (AN). ...
    • closedAccess   Physical activity in anorexia nervosa: How relevant is it to therapy response? 

      Sauchelli, Sarah; Arcelus, Jon; Sánchez, Isabel; Riesco, Nadine; Jiménez-Murcia, Susana; Granero, Roser; Gunnardf, K.; Baños, Rosa Maria; Botella, Cristina; De la Torre, Rafael; Fernández García, José Carlos; Fernández-Real, José Manuel; Frühbeck, Gema; Gómez Ambrosi, Javier; Tinahones Madueño, Francisco Javier; Casanueva, Felipe F.; Menchón, José Manuel; Fernández Aranda, Fernando Elsevier Masson (2015)
      Objective Elevated physical activity has been observed in some patients with anorexia nervosa (AN) despite their emaciated condition. However, its effects on treatment outcome remain unclear. This study aimed to examine ...
    • closedAccess   Relationship between eating styles and temperament in an anorexia nervosa, healthy control, and morbid obesity female sample 

      Baños, Rosa Maria; Cebolla Marti, Ausias; Moragrega Vergara, Inés; Van Strien, T.; Fernández Aranda, Fernando; Agüera, Zaida; De la Torre, Rafael; Casanueva, Felipe F.; Fernández-Real, José Manuel; Fernández García, José Carlos; Frühbeck, Gema; Gómez Ambrosi, Javier; Jiménez-Murcia, Susana; Rodríguez, Roser; Tinahones Madueño, Francisco Javier; Botella, Cristina Elsevier (2014-05-01)
      Objectives: Eating styles have been studied in both Obesity (OB) and Eating Disorders (ED), but they have not been examined in these two weight conditions together. The present study explores differences in eating styles ...
    • closedAccess   Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions 

      Fernández Aranda, Fernando; Agüera, Zaida; Fernández García, José Carlos; Garrido-Sánchez, Lourdes; Alcaide Torres, Juan; Tinahones Madueño, Francisco Javier; Giner-Bartolomé, Cristina; Baños, Rosa Maria; Botella, Cristina; Cebolla Marti, Ausias; De la Torre, Rafael; Fernández-Real, José Manuel; Ortega, Francisco J.; Frühbeck, Gema; Gómez Ambrosi, Javier; Granero, Roser; Islam, Mohamed A.; Giménez Murcia, Susana; Tárrega, Salomé; Menchón, José Manuel; Fagundo, Ana B.; Sancho, Carolina; Estivill, Xavier; Treasure, Janet; Casanueva, Felipe F. Springer (2016-02)
      (1) The objective of this study is to analyze differences in smell–taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, ...
    • openAccess   Transdiagnostic perspective of impulsivity and compulsivity in obesity: from cognitive profile to self-reported dimensions in clinical samples with and without diabetes 

      Testa, Giulia; Mora, Bernat; Camacho-Barcia, Lucía; Granero, Roser; Lucas, Ignacio; Agüera, Zaida; Jiménez-Murcia, Susana; Baños, Rosa Maria; Bertaina-Anglade, Valerie; Botella, Cristina; Bulló, Mònica; Casanueva, Felipe F.; Dalsgaard, Søren; Fernández-Real, José Manuel; Franke, Barbara; Frühbeck, Gema; Fitó, Montserrat; Gómez Martínez, Carlos; Pintó, Xavier; Poelmans, Geert; Tinahones, Francisco J; De la Torre, Rafael; Salas-Salvadó, Jordi; Serra-Majem, Lluis; Vos, Stephanie; Wimberley, Theresa; Fernández Aranda, Fernando MDPI (2021-12-10)
      Impulsive and compulsive behaviors have both been observed in individuals with obesity. The co-occurrence of obesity and type 2 diabetes (T2D) is more strongly associated with impulsivity, although there are no conclusive ...