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The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
(Elsevier, 2019-02-01)
It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...
Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
(Elsevier, 2020-12-30)
Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...
Complement proteins regulating macrophage polarisation on biomaterials
(Elsevier, 2019-09-01)
One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ...
Proteomic evaluation of human osteoblast responses to titanium implants over time
(WileyWiley Periodicals, 2022-08-30)
Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
(Elsevier, 2020)
Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ...
Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
(Elsevier, 2021-06-01)
Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ...
Proteomic analysis of calcium-enriched sol–gel biomaterials
(Springer, 2019-04)
Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...
Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study
(Elsevier, 2022)
The cell–biomaterial interface is highly complex; thousands of molecules and many processes participate in its formation. Growing demand for improved biomaterials has highlighted the need to understand the structure and ...
The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration
(Royal Society of Chemistry, 2022)
Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ...
Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants
(Taylor & Francis, 2017)
Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ...