Listar MED_Articles por título
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Parkinson symptoms and health related quality of life as predictors of costs: a longitudinal observational study with linear mixed model analysis
Public Library of Science (2015)Objective To estimate the magnitude in which Parkinson’s disease (PD) symptoms and health- related quality of life (HRQoL) determined PD costs over a 4-year period. Materials and Methods Data collected during ... -
Parkinson’s disease and autophagy
Hindawi Publishing Corporation (2012)It is generally accepted that a correlation between neurodegenerative disease and protein aggregation in the brain exists; however, a causal relationship has not been elucidated. In neurons, failure of autophagy may result ... -
Participación de las enfermeras clínicas en la formación práctica de estudiantes de Grado en Enfermería
Elsevier (2018-06)Objective: Evaluate the level of participation of clinical nurses from Castellón where Universitat Jaume I nursing students do their clinical clerkship. Identify the variables that may influence clinical nurses’ participation ... -
Patient Decision Aid (PDA) for Patients with Rheumatoid Arthritis Reduces Decisional Confict and Improves Readiness for Treatment Decision Making
Springer (2020)Objectives The aim of this study was to develop and assess the efectiveness of a patient decision aid (PDA) to support treatment decision making in Spanish patients with moderate-to-severe rheumatoid arthritis (RA) who ... -
Patient-physician discrepancy in the perception of immune-mediated inflammatory diseases: rheumatoid arthritis, psoriatic arthritis and psoriasis. A qualitative systematic review of the literature
Public Library of Science (2020)Introduction Recommendations on chronic diseases management emphasise the need to consider patient perspectives and shared decision-making. Discrepancies between patients and physicians’ perspectives on treatment objectives, ... -
Patient-Reported Outcome Measures in Real-World Atopic Dermatitis Studies in Spain: A Systematic Review
Elsevier (2022-08)Atopic dermatitis (AD) is a chronic inflammatory skin disease with symptoms such as pruritus that can be a major burden for patients. Patient-reported outcomes (PRO) complement clinician-reported outcomes in AD. This ... -
Patient-reported outcomes in European spondyloarthritis patients: a systematic review of the literature
Dove Medical Press (2018)Objective: This review aims to summarize the current literature on patient-reported outcomes (PROs) in spondyloarthritis (SpA). Patients and methods: We performed a systematic literature review to identify studies ... -
Patients' and physicians' preferences for type 2 diabetes mellitus treatments in Spain and Portugal: a discrete choice experiment
Dove Medical Press (2015-10)Objective To assess Spanish and Portuguese patients’ and physicians’ preferences regarding type 2 diabetes mellitus (T2DM) treatments and the monthly willingness to pay (WTP) to gain benefits or avoid side effects. M ... -
Patrones de colateralización de los núcleos del rafe y del núcleo incertus al sistema septo-hipocámpico
Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2023)El núcleo incertus (NI), rico en relaxina 3 (rlN3), y los núcleos del rafe, ricos en serotonina (5ht), son unidades modulares de la línea media del tronco cerebral que influyen en diversas funciones cerebrales, entre ... -
Pattern of distribution of serotonergic fibers to the amygdala and extended amygdala in the rat
Wiley (2016-06)As is well recognized, serotonergic (5-HT) fibers distribute widely throughout the forebrain, including the amygdala. Although a few reports have examined the 5-HT innervation of select nuclei of the amygdala in the rat, ... -
Percepción de los pacientes en cuanto al manejo de la fibrosis pulmonar idiopática. Proyecto Explora-IPF
Elsevier (2022)Introduction Idiopathic pulmonary fibrosis (IPF) impacts the life of patients and their families, so it is necessary to ascertain their perception in the approach to their disease. Methods Observational study by means ... -
Perceptions of Oncologists, Healthcare Policy Makers, Patients and the General Population on the Value of Pharmaceutical Treatments in Oncology
Springer (2016)Introduction The purpose of this study was to explore the main factors explaining the relative weight of the different attributes that determine the value of oncologic treatments from the different perspectives of ... -
Perfil de pacientes con mutación BRCA y cáncer de mama
Elsevier (2017)Objective to study patients with breast cancer and BRCA 1 and / or 2 mutations. Material and methods We performed a retrospective study of 28 patients with breast cancer and BRCA 1 and/or 2 mutations between 2010 and 2016. ... -
Perineuronal Net Formation and the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus
Nature Research (2019)In leptin-deficient ob/ob mice, obesity and diabetes are associated with abnormal development of neurocircuits in the hypothalamic arcuate nucleus (ARC)1, a critical brain area for energy and glucose homoeostasis2,3. Because ... -
Peritoneal carcinomatosis index as a predictor of diaphragmatic involvement in stage III and IV ovarian cancer
Dove Medical Press (2018)Objective: To analyze the surgical outcomes and diaphragmatic involvement in stage III and IV ovarian cancer. Patients and methods: All patients with stage III–IV ovarian cancer between January 2013 and January 2016 ... -
Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques
Elsevier (2013-08)Patients with Parkinson's disease show persistent microglial activation in the areas of the brain where the degeneration of dopaminergic neurons takes place. The reason for maintaining this activated state is still unknown, ... -
Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques
Elsevier (2013)Patients with Parkinson's disease show persistent microglial activation in the areas of the brain where the degeneration of dopaminergic neurons takes place. The reason for maintaining this activated state is still unknown, ... -
Perspectives and Potential Applications of Mitochondria-Targeted Antioxidants in Cardiometabolic Diseases and Type 2 Diabetes
John Wiley & Sons (2013)There is abundant evidence to suggest that mitochondrial dysfunction is a main cause of insulin resistance and related cardiometabolic comorbidities. On the other hand, insulin resistance is one of the main characteristics ... -
Photodynamic Inactivation of Staphylococcus aureus Biofilms Using a Hexanuclear Molybdenum Complex Embedded in Transparent polyHEMA Hydrogels
American Chemical Society (2020)Three new photoactive polymeric materials embedding a hexanuclear molybdenum cluster (Bu4N)2[Mo6I8(CH3COO)6] (1) have been synthesized and characterized by means of Fourier-transform infrared spectroscopy (FTIR), ... -
Photodynamic inactivation of Staphylococcus aureus in the presence of aggregation-prone photosensitizers based on BODIPY used at submicromolar concentrations
Elsevier B.V. (2022-08-10)Two new brominated BODIPYs (1 and 2) bearing amino acid-based chains (l-valine for 1, and dimethyl-l-lysine for 2) were synthesized and characterized. In organic solvents, 1 and 2 were fully soluble and showed the photophysical ...