Listar por tema "Fatigue"
Mostrando ítems 1-15 de 15
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Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions
Springer Verlag (2017)Rationale Motivated behavior can be characterized by a substantial exertion of effort, and organisms often make effortrelated decisions based upon analyses of work-related response costs and reinforcement preference. ... -
Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions
Springer Verlag (2017)Rationale Motivated behavior can be characterized by a substantial exertion of effort, and organisms often make effortrelated decisions based upon analyses of work-related response costs and reinforcement preference. ... -
Bases cerebrales de la fatiga en pacientes de esclerosis múltiple. Una revisión bibliográfica
Universitat Jaume I (2018-10-01)Fatigue is one of the most disabling symptoms of Multiple Sclerosis (MS), and greatly affects the quality of life of patients. Knowing the causes of fatigue is complicated due to the multitude ... -
Behavioral and dopamine transporter binding properties of the modafinil analog (S, S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding
Springer (2020)Rationale Atypical dopamine (DA) transport blockers such as modafinil and its analogs may be useful for treating motivational symptoms of depression and other disorders. Previous research has shown that the DA depleting ... -
Caffeine and Selective Adenosine Receptor Antagonists as New Therapeutic Tools for the Motivational Symptoms of Depression
Frontiers Media (2018-06-01)Major depressive disorder is one of the most common and debilitating psychiatric disorders. Some of the motivational symptoms of depression, such anergia (lack of self-reported energy) and fatigue are relatively resistant ... -
Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat
Springer Verlag (2016)Rationale Effort-related motivational symptoms, such as anergia, psychomotor retardation, and fatigue, are an important aspect of depression and other disorders. Motivational symptoms are resistant to some treatments, ... -
Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization
Springer Verlag (2016)Rationale Motivational dysfunctions such as anergia, fatigue, and reduced effort expenditure are common in patients with depression and other disorders. Pro-inflammatory cytokines are implicated in depression, and ... -
Evaluation of human prehension using grasp quality measures
(2012)One of the main features of the human hand is its grasping ability. Robot grasping has been studied for years and different quality measures have been proposed to evaluate the stability and manipulability of grasps. ... -
Evaluation of the effort-related motivational effects of the novel dopamine uptake inhibitor PRX-14040
Elsevier (2016)Psychiatric disorders are often marked by effort-related motivational symptoms such as anergia, fatigue, psychomotor retardation, and alterations in effort-based decision making. Animal studies of effort-related choice ... -
Partial reversal of the effort-related motivational effects of tetrabenazinewith the MAO-B inhibitor deprenyl (selegiline): Implications for treatingmotivational dysfunctions
Elsevier (2018)People with depression and Parkinsonism frequently show effort-related motivational symptoms, such as an-ergia, psychomotor retardation, and fatigue. Tasks that assess effort-related choice are being used as animalmodels of ... -
Premolars restored with posts of different materials: fatigue analysis
The Japanese Society for Dental Materials and Devices (2011-11-30)Previous works studied the effect of the material and the dimensions of the post on the biomechanical performance (fracture strength and stress distribution) of restored teeth, under static loads. The aim of this work was ... -
The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding
Frontiers Media (2019-06-28)Animal studies of effort-based choice behavior are being used to model effort-related motivational dysfunctions in humans. With these procedures, animals are offered a choice between high-effort instrumental actions ... -
The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists
Elsevier (2015)Mesolimbic dopamine (DA), particularly in the nucleus accumbens, is a critical component of the brain circuitry involved in behavioral activation and effort-related processes. Although much is known about the characteristics of ... -
The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: reversal with the adenosine A2A antagonist MSX-3 and the catecholamine uptake blocker bupropion
Springer Verlag (2015)Rationale Depressed people show effort-related motivational symptoms, such as anergia, retardation, lassitude, and fatigue. Animal tests can model these motivational symptoms, and the present studies characterized the ... -
Voxelwise assessment of the regional distribution of damage in the brains of patients with multiple sclerosis and fatigue
American Society of Neuroradiology (2011-03-10)BACKGROUND AND PURPOSE: Fatigue affects up to 90% of patients with MS. We assessed the regional distribution of lesions and atrophy of the normal-appearing WM and GM in patients with RRMS with fatigue compared with HC and ...