Browsing PSB_Articles by Author "77013a8c-91bc-496c-9cdd-25916bbbee08"
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A Working Hypothesis for the Role of the Cerebellum in Impulsivity and Compulsivity
MIQUEL, MARTA; Nicola, Saleem; Gil-Miravet, Isis; Guarque-Chabrera, Julian; Sanchez-Hernandez, Aitor Frontiers Media (2019-05)Growing evidence associates cerebellar abnormalities with several neuropsychiatric disorders in which compulsive symptomatology and impulsivity are part of the disease pattern. Symptomatology of autism, addiction, ... -
Amino acid tissue levels and GABAa receptor binding in the developing rat cerebellum following status epilepticus
MIQUEL, MARTA; López Meraz, María Leonor; Rocha, Luisa L.; Ortega, Jenny C.; Pérez-Estudillo, César A.; García, Luis I.; Hernández, María Elena; Manzo, Jorge Elsevier (2012)Incidence of status epilepticus (SE) is higher in children than in adults and SE can be induced in developing rats. The cerebellum can be affected after SE; however, consequences of cerebellar amino acid transmission ... -
Bases biológicas y neurales de las preferencias de Pareja En Roedores: Modelos Para Entender Vínculos Afectivos En Humanos
MIQUEL, MARTA; Hernández, María Elena; García, Luis I; Manzo, Jorge (2008) -
Beyond the basal ganglia: cFOS expression in the cerebellum in response to acute and chronic dopaminergic alterations
Herrera-Meza, G.; Aguirre Manzo, Luisa; Coria Ávila, Genaro A.; López Meraz, María Leonor; Toledo, Rebeca; Manzo, Jorge; García, Luis I.; MIQUEL, MARTA Elsevier (2014)The suggestion of an anatomical and functional relationship between the basal ganglia and cerebellum is recent. Traditionally, these structures were considered as neuronal circuits working separately to organize and control ... -
Brain activation by an olfactory stimulus paired with juvenile play in female rats
Paredes Ramos, Pedro; Bowers, J. M.; McCarthy, M. M.; MIQUEL, MARTA; Manzo, Jorge; Coria Ávila, Genaro A. Elsevier (2014)We have previously shown that reward experienced during social play at juvenile age can be paired with artificial odors, and later in adulthood facilitate olfactory conditioned partner preferences (PP) in female rats. ... -
Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity
Sorg, Barbara A.; Berretta, Sabina; Blacktop, Jordan; Fawcett, James W.; Kitagawa, Hiroshi; Kwok, Jessica C.F.; MIQUEL, MARTA Society for Neuroscience (2016-11)Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain neurons in the CNS during development and control plasticity in the adult CNS. They appear to contribute to a wide range of ... -
Cerebellar hallmarks of conditioned preference for cocaine
Carbó Gas, María; Vázquez Sanromán, Dolores; Gil-Miravet, Isis; De las Heras-Chanes, Joan; Coria Ávila, Genaro A.; Manzo, Jorge; Sanchis-Segura, Carla; MIQUEL, MARTA Elsevier (2014)Pavlovian conditioning tunes the motivational drive of drug-associated stimuli, fostering the probability of those environmental stimuli to promote and trigger drug seeking and taking. Interestingly, different areas in ... -
Cerebellar perineuronal nets in cocaine-induced pavlovian memory: Site matters
Carbó Gas, María; Moreno Rius, Josep; Guarque-Chabrera, Julian; Vázquez Sanromán, Dolores; Gil-Miravet, Isis; Carulli, Daniela; Hoebeek, Freek; De Zeeuw, Chris; Sanchis-Segura, Carla; MIQUEL, MARTA Elsevier (2017-07-14)One of the key mechanisms for the stabilization of synaptic changes near the end of critical periods for experience-dependent plasticity is the formation of specific lattice extracellular matrix structures called perineuronal ... -
Cocaine-induced plasticity in the cerebellum of sensitised mice
Vázquez Sanromán, Dolores; Carbó Gas, María; Leto, Ketty; Cerezo García, Miguel; Gil-Miravet, Isis; Sanchis-Segura, Carla; Carulli, Daniela; Rossi, Ferdinando; MIQUEL, MARTA Springer Verlag (2015)Rationale Prior research has accumulated a substantial amount of evidence on the ability of cocaine to produce short- and long-lasting molecular and structural plasticity in the corticostriatal-limbic circuitry. However, ... -
Cocaine-Induced Preference Conditioning: a Machine Vision Perspective
Traver Roig, Vicente Javier; Pla, Filiberto; MIQUEL, MARTA; Carbó Gas, María; Gil-Miravet, Isis; Guarque-Chabrera, Julian Springer (2018)Existing work on drug-induced synaptic changes has shown that the expression of perineuronal nets (PNNs) at the cerebellar cortex can be regulated by cocaine-related memory. However, these studies on animals have mostly ... -
Conducta sexual y neurogénesis adulta: ¿por qué estudiar el cerebelo?
Aguirre, Carmen; Vázquez Sanromán, Dolores; Coria Ávila, Genaro A.; Toledo, Rebeca; López Meraz, María Leonor; Manzo, Jorge; MIQUEL, MARTA Universidad Veracruzana, Dirección General de Investigaciones (2011)La neurogénesis adulta es la formación de nuevas neuronas en cerebro adulto y constituye una respuesta de adaptación al ambiente o a cambios impuestos sobre la fisiología neuronal. Su regulación se lleva a cabo por factores ... -
Consensus Paper: Cerebellum and Reward
Manto, Mario; Adamaszek, Michael; Apps, Richard; Carlson, Erik; Guarque-Chabrera, Julian; Heleven, Elien; Kakei, Shinji; Khodakhah, Kamran; Kuo, Sheng-Han; Lin, Chi-Ying; Joshua, Mati; MIQUEL, MARTA; Mitoma, Hiroshi; Larry, Noga; Péron, Julie Anne; Pickford, Jasmine; Schutter, Dennis; Singh, Manpreet K.; Tan, Tommy; Tanaka, Hirokazu; tsai, peter; Van Overwalle, Frank; Yamashiro, Kunihiko Springer (2024-05-06)Cerebellum is a key-structure for the modulation of motor, cognitive, social and afective functions, contributing to automatic behaviours through interactions with the cerebral cortex, basal ganglia and spinal cord. The ... -
Encendiendo y apagando el cerebelo para cambiar la preferencia por los contextos relacionados con las drogas
Melchor Eixea, Ignasi; MIQUEL, MARTA Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2023) -
From back to front: A functional model for the cerebellar modulation in the establishment of conditioned preferences for cocaine‐related cues
Gil-Miravet, Isis; Melchor Eixea, Ignasi; Arias-Sandoval, Edgar; Vasquez‐Celaya, Lizbeth; Olucha-Bordonau, Francisco E; MIQUEL, MARTA Wiley (2019)It is now increasingly clear that the cerebellum may modulate brain functions altered in drug addiction. We previously demonstrated that cocaine‐induced conditioned preference increased activity at the dorsal posterior ... -
Have we been ignoring the elephant in the room? Seven arguments for considering the cerebellum as part of addiction circuitry
MIQUEL, MARTA; Vázquez Sanromán, Dolores; Carbó Gas, María; Gil-Miravet, Isis; Sanchis-Segura, Carla; Carulli, Daniela; Manzo, Jorge; Coria Ávila, Genaro A. Elsevier (2016)Addiction involves alterations in multiple brain regions that are associated with functions such as memory, motivation and executive control. Indeed, it is now well accepted that addictive drugs produce long-lasting molecular ... -
Inducción del temblor mandibular por lesión electrolítica del estriado ventrolateral y por el tratamiento subcrónico con haloperidol en rata macho: un contraste electromiográfico
Herrera-Meza, G.; Manzo, Jorge; Hernández, María Elena; MIQUEL, MARTA; García, Luis I. Elsevier (2014)El temblor mandibular (TM) en la rata es inducido farmacológicamente por la manipulación dopaminérgica estriatal y por lesión del estriado ventrolateral (EVL). Este temblor tiene características neuroquímicas, anatómicas ... -
Induction of brain cytochrome P450 2E1 boosts the locomotor-stimulating effects of ethanol in mice
Ledesma Llorente, Juan Carlos; MIQUEL, MARTA; Pascual, María; Guerri, Consuelo; González Aragón, Carlos Manuel Elsevier (2014)In the central nervous system ethanol (EtOH) is metabolized into acetaldehyde by different enzymes. Brain catalase accounts for 60% of the total production of EtOH-derived acetaldehyde, whereas cerebral cytochrome P450 2E1 ... -
Involvement of brain catalase activity in the acquisition of ethanol-induced conditioned place preference
Font Hurtado, Laura; MIQUEL, MARTA; González Aragón, Carlos Manuel Elsevier (2008)It has been suggested that some of the behavioral effects produced by ethanol are mediated by its first metabolite, acetaldehyde. The present research addressed the hypothesis that catalase-dependent metabolism of ethanol ... -
Involvement of the beta-endorphin neurons of the hypothalamic arcuate nucleus in ethanol-induced place preference conditioning in mice
Pastor Medall, Raúl; Font Hurtado, Laura; MIQUEL, MARTA; Phillips, Tamara J.; González Aragón, Carlos Manuel Wiley (2011-10-20)Background: Increasing evidence indicates that mu- and delta-opioid receptors are decisively involved in the retrieval of memories underlying conditioned effects of ethanol. The precise mechanism by which these receptors ... -
Involving the cerebellum in cocaine-induced memory: pattern of CFOS expression in mice trained to acquire conditioned preference for cocaine
Carbó Gas, María; Vázquez Sanromán, Dolores; Aguirre Manzo, Luisa; Coria Ávila, Genaro A.; Manzo, Jorge; Sanchis-Segura, Carla; MIQUEL, MARTA Wiley (2014-01)Because of its primary role in drug-seeking, consumption and addictive behaviour, there is a growing interest in identifying the neural circuits and molecular mechanisms underlying the formation, maintenance and retrieval ...