• openAccess   Inspiratory and Lower-Limb Strength Importance in Mountain Ultramarathon Running. Sex Differences and Relationship with Performance 

      MARTINEZ-NAVARRO, IGNACIO; Montoya-Vieco, Antonio; Collado-Boira, Eladio; Hernando, Barbara; Hernando, Carlos MDPI (2020)
      The study was aimed at comparing lower-limb strength and respiratory parameters between male and female athletes and their interaction with performance in a 107 km mountain ultramarathon. Forty seven runners (29 males and ...
    • closedAccess   Inspiratory Muscle Function and Exercise Capacity in Patients with Heart Failure with Preserved Ejection Fraction 

      Palau, Patricia; Domínguez Mafé, Eloy; Núñez, Eduardo; Ramón, José María; López, Laura; Melero, Joana; Bellver, Alejandro; Chorro, Francisco J.; Bodí, Vicent; Bayes-Genis, Antoni; Sanchis, Juan; Núñez, Julio Elsevier (2017-06)
      Background Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by impaired exercise capacity resulting from dyspnea and fatigue. The pathophysiological mechanisms underlying the ...
    • closedAccess   Inspiratory Muscle Training and Functional Electrical Stimulation for Treatment of Heart Failure With Preserved Ejection Fraction: Rationale and Study Design of a Prospective Randomized Controlled Trial 

      Palau, Patricia; Domínguez Mafé, Eloy; López, Laura; Heredia, Raquel; González, Jessika; Ramón, José María; Serra, Pilar; Santas, Enrique; Bodí, Vicent; Sanchis, Juan; Chorro, Francisco J.; Núñez, Julio Wiley (2016-08-02)
      Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent form of heart failure in developed countries. Regrettably, there is no evidence-based effective therapy for HFpEF. We seek to evaluate ...
    • openAccess   Intensive longitudinal modelling predicts diurnal activity of salivary alpha-amylase 

      Rosel, Jesús F.; Jara Jiménez, Pilar; Machancoses, Francisco H.; Pallarés, Jacinto; Torrente, Pedro; Puchol, Sara; Canales, Juan J. Public Library of Science (2019)
      Salivary alpha-amylase (sAA) activity has been widely used in psychological and medical research as a surrogate marker of sympathetic nervous system activation, though its utility remains controversial. The aim of this ...
    • closedAccess   Interobserver discrepancy in liver fibrosis using transient elastography 

      Roca Villanueva, Bernardino; Resino, Elena; Torres, V.; Herrero, E.; Penades, M. John Wiley & Sons (2012)
      Transient elastography is a useful method to assess liver fibrosis, but uncertainties still exist regarding reliability and reproducibility of the technique. We aimed to improve knowledge on interobserver variability with ...
    • openAccess   Intervention of an Upgraded Ventilation System and Effects of the COVID-19 Lockdown on Air Quality at Birmingham New Street Railway Station 

      Clegg, Matt; Thornes, John; Banerjee, Debasree; Mitsakou, Christina; Quaiyoom, Azhar; Delgado-Saborit, Juana Maria; Phalkey, Revati MDPI (2022-01-05)
      High NO2 concentrations (long term average of 383 µg/m3 in 2016/2017) recorded at Birmingham New Street railway station have resulted in the upgrade of the bi-directional fan system to aid wind dispersion within the ...
    • openAccess   Intraoperative haemodynamic optimisation using the Hypotension Prediction Index and its impact on tissular perfusion: a protocol for a randomised controlled trial 

      Lorente Olazábal, Juan Victor; Jimenez, Ignacio; Ripollés-Melchor , Javier; Becerra, Alejandra; Wesselink, Wilbert; Reguant, Francesca; Mojarro, Irene; Fuentes, Maria de los Angeles; Abad-Motos, Ane; Agudelo, Elizabeth; Machancoses, Francisco H.; Callejo, Paula; Bosch, Joan; Monge, Manuel Ignacio BMJ Publishing Group (2022-06)
      Introduction: Intraoperative arterial hypotension is associated with poor postoperative outcomes. The Hypotension Prediction Index (HPI) developed using machine learning techniques, allows the prediction of arterial ...
    • closedAccess   Intraspecific Communication Through Chemical Signals in Female Mice: Reinforcing Properties of Involatile Male Sexual Pheromones 

      Martínez-Ricós, Joana; Agustín-Pavón, Carmen; Lanuza, Enrique; Martinez-Garcia, Fernando Oxford University Press (2007)
      In rodents, social and reproductive behaviors critically depend on chemical signals, including sexual pheromones that have been suggested (but not demonstrated) to be rewarding. In this work, we analyze this issue by ...
    • closedAccess   Intravesical mini-laparoscopic repair of vesicovaginal fistulas 

      Llueca, Antoni; Herraiz Roda, José Luis; Rodrigo, Miguel; Mazzouzi, Yasmin; Piquer Simó, Dolors; Guijarro Colomer, M.; Cañete, Arhoa; Escrig-Sos, Javier Springer Verlag (2015)
      Vesicovaginal fistulas (VVF) constitute the most common type of genitourinary fistulas. In developed countries, VVF are almost always iatrogenic and frequently a secondary result of gynecological surgery. Some minimally ...
    • openAccess   Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma 

      Santos, Alonso; Ribas, Gloria; Ibarrola-Villava, Maider; Peña Chilet, María; Martinez-Cadenas, Conrado; Gardeazabal, Jesús; Careaga, Jesús María; Pérez-Yarza, Gorka; Sánchez-Díez, Ana; Ratón-Nieto, Juan Antonio; Arroyo-Berdgo, Yoana; Carretero, Gregorio; Martín González, Manuel; Gómez Fernández, Cristina; Nagore, Eduardo; Asumendi, Aintzane; Boyano, Dolores Public Library of Science (2014)
      Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
    • openAccess   Involvement of nitric oxide in the mitochondrial action of efavirenz: a differential effect on neurons and glial cells 

      Apostolova, Nadezda; Funes, Haryes A.; Blas García, Ana; Alegre, Fernando; Polo, Míriam; Esplugues Mota, Juan V. Oxford University Press (2014-12)
      The anti-human immunodeficiency virus (HIV) drug efavirenz (EFV) alters mitochondrial function in cultured neurons and glial cells. Nitric oxide (NO) is a mediator of mitochondrial dysfunction associated with HIV central ...
    • openAccess   Involvement of the Nucleus Incertus and Relaxin-3/RXFP3 Signaling System in Explicit and Implicit Memory 

      Gil-Miravet, Isis; Mañas-Ojeda, Aroa; Ros Bernal, Francisco; Castillo-Gómez, Esther; Albert Gasco, Hector; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2021-03-18)
      Telencephalic cognitive and emotional circuits/functions are strongly modulated by subcortical inputs. The main focus of past research on the nature of this modulation has been on the widespread monoamine projections to ...
    • closedAccess   Iodine Supplementation During Pregnancy and Infant Neuropsychological: INMA Mother and Child Cohort Study 

      Rebagliato, Marisa; Murcia, Mario; Álvarez Pedrerol, Mar; Espada, Mercedes; Fernández Somoano, Ana; Lertxundi, Nerea; Navarrete-Muñoz, Eva María; Forns, Joan; Aranbarri, Aritz; Llop, Sabrina; Julvez, Jordi; Tardon, Adonina; Ballester, Ferran Oxford University Press (2013-04)
      Iodine supplementation during pregnancy is a common practice in developed countries. However, scant evidence is available regarding the safety and effectiveness of maternal iodine supplementation with regard to child ...
    • closedAccess   Iron deficiency and short-term adverse events in patients with decompensated heart failure 

      Palau, Patricia; Llàcer, Pau; Domínguez Mafé, Eloy; Tormo, Juan Pablo; Zakarne, Rim; Mollar, Anna; Martínez, Ana; Miñana, Gema; Santas, Enrique; Almenar-Bonet, Luis; Fácila, Lorenzo; De la Espriella, Rafael; Núñez, Eduardo; Manzano, Luis; Bayes-Genis, Antoni; Núñez, Julio Springer (2021-03-15)
      Background: For patients with heart failure (HF), iron deficiency (ID) is a common therapeutic target. However, little is known about the utility of transferrin saturation (TSAT) or serum ferritin for risk stratification ...
    • openAccess   IRS-2 deficiency impairs NMDA receptor-dependent long-term potentiation 

      Sánchez-Pérez, Ana María; Martín, Eduardo D.; Trejo, José Luis; Martín Aldana, Juan Antonio; Cano Jaimez, Marife; Pons, Sebastian; Acosta Umanzor, Carlos; Menes, Lorena; White, Morris F.; Burks, Deborah J. Oxford University Press (2012-08)
      The beneficial effects of insulin and insulin-like growth factor I on cognition have been documented in humans and animal models. Conversely, obesity, hyperinsulinemia, and diabetes increase the risk for neurodegenerative ...
    • closedAccess   Is Glycemic Control Modulating Endoplasmic Reticulum Stress in Leukocytes of Type 2 Diabetic Patients? 

      Rovira Llopis, Susana; Bañuls, Celia; Apostolova, Nadezda; Morillas, Carlos; Hernández Mijares, Antonio; Rocha, Milagros; Víctor, Víctor M. Mary Ann Liebert Inc. (2014-10-06)
      Oxidative and endoplasmic reticulum (ER) stress is related to type 2 diabetes (T2D), but the influence of glycemic control on these parameters and its relationship with leukocyte-endothelial interactions is not known. In ...
    • openAccess   Is the Physician’s Behavior in Dyslipidemia Diagnosis in Accordance with Guidelines? Cross-Sectional Escarval Study 

      Palazón-Bru, Antonio; Gil-Guillén, Vicente F; Orozco Beltrán, Domingo; Pallarés-Carratalá, Vicente; Valls Roca, Francisco; Sanchis-Domenech, Carlos; Martin-Moreno, Jose M.; Redón, Josep; Navarro Pérez, Jorge; Fernández Giménez, Antonio; Pérez Navarro, Ana M.; Trillo, José L.; Usó, Ruth; Ruiz, Elías Public Library of Science (2014)
      Background: Clinical inertia has been defined as mistakes by the physician in starting or intensifying treatment when indicated. Inertia, therefore, can affect other stages in the healthcare process, like diagnosis. The ...
    • openAccess   Is There A Role for Abscisic Acid, A Proven Anti-Inflammatory Agent, in the Treatment of Ischemic Retinopathies? 

      Baliño, Pablo; Gomez-Cadenas, Aurelio; López Malo, Daniel; Romero, Francisco J.; Muriach, Maria MDPI (2019)
      Ischemic retinopathies (IRs) are the main cause of severe visual impairment and sight loss, and are characterized by loss of blood vessels, accompanied by hypoxia, and neovascularization. Actual therapies, based on ...
    • openAccess   Is There a Role of Beetroot Consumption on the Recovery of Oxidative Status and Muscle Damage in Ultra-Endurance Runners? 

      Vilar Yebra, Eva; Collado-Boira, Eladio; Guerrero, Carlos; Folch Ayora, Ana; Salas-Medina, Pablo; Hernando, Carlos; Baliño, Pablo; Muriach, Maria MDPI (2024-02)
      (1) Background: Ultra-endurance exercise involves a high physical impact, resulting in muscle damage, inflammatory response and production of free radicals that alter the body’s oxidative state. Supplementation with ...
    • closedAccess   Isolated Partial Congenital Absence of the Pericardium: A Familial Presentation 

      Palau, Patricia; Domínguez Mafé, Eloy; García González, Pilar; Gallego Peris, Jorge; Bosch, María José; Sieso, Eduardo Elsevier (2015)
      Congenital defects of the pericardium are uncommon heart abnormalities. Most of the patients are asymptomatic and are usually diagnosed incidentally. Complications are more common in partial absence than in complete absence ...