Listar Departament: Medicina por título

Mostrando ítems 454-473 de 673

    • openAccess   Percepción de los pacientes en cuanto al manejo de la fibrosis pulmonar idiopática. Proyecto Explora-IPF 

      Peña Miguel, Teresa; Ortoll Polo, Virginia; Lizán, Luis; Armengol, Silvia; Ramón, Alba Elsevier (2022)
      Introduction Idiopathic pulmonary fibrosis (IPF) impacts the life of patients and their families, so it is necessary to ascertain their perception in the approach to their disease. Methods Observational study by means ...

    • openAccess   Perceptions of Oncologists, Healthcare Policy Makers, Patients and the General Population on the Value of Pharmaceutical Treatments in Oncology 

      Sacristán, José Antonio; Lizán, Luis; Comellas, Marta; Garrido, Pilar; Avendaño, Cristina; Cruz-Hernández, Juan J.; Espinosa, Javier; Dilla, Tatiana Springer (2016)
      Introduction The purpose of this study was to explore the main factors explaining the relative weight of the different attributes that determine the value of oncologic treatments from the different perspectives of ...

    • closedAccess   Perfil de pacientes con mutación BRCA y cáncer de mama 

      Martínez Gómez, Elena; Arnanz Velasco, Fuencisla; Cano Cuetos, Ana; Garrido González, Nuria; Zapico Goñi, Álvaro; Llueca, Antoni Elsevier (2017)
      Objective to study patients with breast cancer and BRCA 1 and / or 2 mutations. Material and methods We performed a retrospective study of 28 patients with breast cancer and BRCA 1 and/or 2 mutations between 2010 and 2016. ...

    • openAccess   Perineuronal Net Formation and the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus 

      Mirzadeh, Zaman; Alonge, Kimberly; Cabrales, Elaine; Herranz-Pérez, Vicente; Scarlett, Jarrad M.; Brown, Jenny M.; Hassouna, Rim; Matsen, Miles E.; Nguyen, Hong T.; García-Verdugo, Jose Manuel; Zeltser, Lori; Schwartz, Michael Nature Research (2019)
      In leptin-deficient ob/ob mice, obesity and diabetes are associated with abnormal development of neurocircuits in the hypothalamic arcuate nucleus (ARC)1, a critical brain area for energy and glucose homoeostasis2,3. Because ...

    • openAccess   Peritoneal carcinomatosis index as a predictor of diaphragmatic involvement in stage III and IV ovarian cancer 

      Llueca, Antoni; Serra Rubert, Anna; Herraiz, José Luis; Rivadulla, Isabel; Gómez-Quiles, Luis; Gilabert-Estellés, Juan; Escrig-Sos, Javier Dove Medical Press (2018)
      Objective: To analyze the surgical outcomes and diaphragmatic involvement in stage III and IV ovarian cancer. Patients and methods: All patients with stage III–IV ovarian cancer between January 2013 and January 2016 ...

    • closedAccess   Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques 

      Barcia, Carlos; Ros Gómez, Carmen María; Ros Bernal, Francisco; Gómez, Aurora; Annese, Valentina; Carrillo de Sauvage, María Ángeles; Yuste Jiménez, José Enrique; Campuzano Brando, Carmen María; De Pablos, Vicente; Fernández Villalba, Emiliano; Herrero Ezquerro, María Trinidad Elsevier (2013-08)
      Patients with Parkinson's disease show persistent microglial activation in the areas of the brain where the degeneration of dopaminergic neurons takes place. The reason for maintaining this activated state is still unknown, ...

    • openAccess   Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques 

      Barcia, Carlos; Ros Gómez, Carmen María; Ros Bernal, Francisco; Gómez, Aurora; Annese, Valentina; Carrillo-de Sauvage, María Ángeles; Yuste Jiménez, José Enrique; Campuzano Brando, Carmen María; De Pablos, Vicente; Fernández Villalba, Emiliano; Herrero Ezquerro, María Trinidad Elsevier (2013)
      Patients with Parkinson's disease show persistent microglial activation in the areas of the brain where the degeneration of dopaminergic neurons takes place. The reason for maintaining this activated state is still unknown, ...

    • openAccess   Perspectives and Potential Applications of Mitochondria-Targeted Antioxidants in Cardiometabolic Diseases and Type 2 Diabetes 

      Rocha, Milagros; Apostolova, Nadezda; Herance, Jose Raul; Rovira Llopis, Susana; Hernández Mijares, Antonio; Víctor, Víctor M. John Wiley & Sons (2013)
      There is abundant evidence to suggest that mitochondrial dysfunction is a main cause of insulin resistance and related cardiometabolic comorbidities. On the other hand, insulin resistance is one of the main characteristics ...

    • openAccess   Photodynamic Inactivation of Staphylococcus aureus Biofilms Using a Hexanuclear Molybdenum Complex Embedded in Transparent polyHEMA Hydrogels 

      López López, Noelia; Muñoz Resta, Ignacio; de Llanos Frutos, Rosa; Miravet, Juan; Mikhaylov, Maxim; Sokolov, Maxim N.; Ballesta-Mudarra, Sofia; García-Luque, Isabel; Galindo, Francisco American Chemical Society (2020)
      Three new photoactive polymeric materials embedding a hexanuclear molybdenum cluster (Bu4N)2[Mo6I8(CH3COO)6] (1) have been synthesized and characterized by means of Fourier-transform infrared spectroscopy (FTIR), ...

    • openAccess   Photodynamic inactivation of Staphylococcus aureus in the presence of aggregation-prone photosensitizers based on BODIPY used at submicromolar concentrations 

      Navarro Barreda, Diego; de Llanos Frutos, Rosa; Miravet, Juan; Galindo, Francisco Elsevier B.V. (2022-08-10)
      Two new brominated BODIPYs (1 and 2) bearing amino acid-based chains (l-valine for 1, and dimethyl-l-lysine for 2) were synthesized and characterized. In organic solvents, 1 and 2 were fully soluble and showed the photophysical ...

    • openAccess   Physicians’ perception of oral nutritional supplement acceptance and tolerability in malnourished outpatients: PerceptiONS study 

      Pedrianes-Martín, Pablo B.; Dassen-de-Monzo, C.; Guardia Baena, Juan Manuel; Riestra, María; Salom Vendrell, Christian; PerceptiONS Group; Calvo-Barbero, A.; Lizán, Luis MDPI (2023-02-28)
      Malnutrition is a common condition associated with various pathologies such as infections, neoplasms and digestive system disorders. Patients can be managed using different strategies, which include dietary modifications ...

    • closedAccess   Plasma neutrophil gelatinase-associated lipocalin and long-term mortality in patients with acute heart failure and normal renal function 

      Miñana, Gema; Rumiz, Eva; Palau, Patricia; Valero, Ernesto; Bodí, Vicent; Núñez, Eduardo; Sanchis, Juan; Núñez, Julio Elsevier (2016)
      Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a renal tubular marker for early renal dysfunction [1]. Recent studies highlighted its role in predicting acute kidney injury (AKI) and clinical outcomes in ...

    • openAccess   Polylactic Acid Nanofiber Membranes Grafted with Carbon Nanotubes with Enhanced Mechanical and Electrical Properties 

      Gisbert Roca, Fernando; Martínez Ramos, Cristina; Ivashchenko, Sergiy; García Bernabé, Abel; Compañ, Vicente; Monleón Pradas, Manuel American Chemical Society (2023-08-11)
      Electroconductive materials based on poly(lactic acid) (PLA) electrospinning membranes grafted with carbon nanotubes (CNTs) functionalized with the carboxylic group R–COOH have been obtained. PLA electrospun membranes were ...

    • openAccess   Polymorphisms in ABC Transporter Genes and Concentrations of Mercury in Newborns – Evidence from Two Mediterranean Birth Cohorts 

      Llop, Sabrina; Engström, Karin; Ballester, Ferran; Franforte, Elisa; Alhamdow, Ayman; Pisa, Federica; Tratnik, Janja Snoj; Mazej, Datja; Murcia, Mario; Rebagliato, Marisa; Bustamante, Mariona; Sunyer Deu, Jordi; Sofianou-Katsoulis, Aikaterini; Prasouli, Alexia; Antonopoulou, Eleni; Antoniadou, Ioanna; Nakou, Sheena; Barbone, Fabio; Horvat, Milena; Broberg, Karin Public Library of Science (2014)
      Background: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. Objective: ...

    • openAccess   Pooled Time Series Modeling Reveals Smoking Habit Memory Pattern 

      Rosel, Jesús F.; Elipe Miravet, Marcel; Elósegui, Eduardo; Flor Arasil, Patricia; Machancoses, Francisco H.; Pallarés, Jacinto; Puchol, Sara; Canales, Juan J. Frontiers Media (2020-02-19)
      Smoking is a habit that is hard to break because nicotine is highly addictive and smoking behavior is strongly linked to multiple daily activities and routines. Here, we explored the effect of gender, age, day of the ...

    • closedAccess   Poor mothers, unhealthy children: the transmission of health inequalities in the INMA study, Spain 

      Larrañaga, Isabel; SANTA MARINA, LORETO; Molinuevo Auzmendi, Amaia; Álvarez Pedrerol, Mar; Fernández Somoano, Ana; Jiménez Zabala, Ana; Rebagliato, Marisa; Rodríguez-Bernal, Clara L.; Tardon, Adonina; Vrijheid, Martine; Ibarluzea, Jesus Oxford University Press (2019-06)
      Background The health of pregnant women and their fetuses are especially sensitive to socioeconomic conditions. This study analyzes the impact of maternal socioeconomic status (SES), evaluated by occupation and maternal ...

    • closedAccess   Posicionamiento SEMERGEN en el abordaje de la insuficiencia cardíaca crónica en atención primaria 

      Castillo Moraga, María José; Turégano-Yedro, Miguel; Pallarés-Carratalá, Vicente; Seoane-Vicente, M.C.; Serrano-Cumplido, A.; Ruiz-García, A.; Martin-Rioobó, E.; Escobar-Cervantes, C.; Polo-García, J.; Barrios, V. Elsevier (2022)
      La insuficiencia cardíaca (IC) es un problema de salud pública que genera una gran carga asistencial tanto hospitalaria como en atención primaria (AP). La publicación de numerosos estudios sobre IC durante los últimos ...

    • openAccess   Post-event follow-up costs in patients with atherosclerotic cardiovascular disease in Spain 

      Martínez López, Icíar; GOMEZ CEREZO, JORGE FRANCISCO; Gámez, José Mª; Egocheaga Cabello, Isabel; Castellanos, María del Mar; Campuzano Ruiz, Raquel; barrios, vivencio; Pallarés-Carratalá, Vicente; Rodríguez, José Manuel; Morant Talamante, Nuria; Parrondo, Javier; Mostaza, José María Frontiers (2024)
      Introduction: Atherosclerotic cardiovascular disease (ASCVD) is one of the main causes of morbidity and mortality in developed countries and entails high resources use and costs for health systems. The risk of suffering ...

    • openAccess   Postnatal development of the relaxin-3 innervation of the rat medial septum 

      ROS, FRANCISCO; Gil-Miravet, Isis; Lucerón Morales, Jorge; Navarro Sánchez, Mónica; Castillo-Gómez, Esther; Gundlach, Andrew Lawrence; Olucha-Bordonau, Francisco E Frontiers Media (2023)
      Introduction: The septal area provides a rich innervation to the hippocampus regulating hippocampal excitability to different behavioral states and modulating theta rhythmogenesis. However, little is known about the ...

    • openAccess   Postnatal exposure to mercury and neuropsychological development among preschooler children 

      Llop, Sabrina; Murcia, Mario; Amorós Salvador, Rubén; Julvez, Jordi; SANTA MARINA, LORETO; Soler-Blasco, Raquel; Rebagliato, Marisa; Iñiguez, Carmen; Aguinagalde, Xabier; Iriarte, Gorka; Lopez-Espinosa, Maria-Jose; Andiarena, Ainara; Gonzalez, Llúcia; Vioque, Jesus; Sunyer Deu, Jordi; Ballester, Ferran Springer (2020-03-13)
      The objective of this study was to describe the postnatal exposure to Hg and to evaluate its association with neuropsychological development among preschool children. The study population are 4–5 years old children (n = ...