Chromatographic determination of antiparasitic drugs in plasma samples for the treatment of STH infections
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Título
Chromatographic determination of antiparasitic drugs in plasma samples for the treatment of STH infectionsAutoría
Tutor/Supervisor; Universidad.Departamento
Esteve Romero, Josep Salvador; Universitat Jaume I. Departament de Química Física i AnalíticaFecha de publicación
2019-10Editor
Universitat Jaume IResumen
The main objective of this final degree work was to develop a new simple, fast,
selective and reliable analytical method for the determination of two antiparasitic drugs,
using micellar liquid chromatography (MLC) ... [+]
The main objective of this final degree work was to develop a new simple, fast,
selective and reliable analytical method for the determination of two antiparasitic drugs,
using micellar liquid chromatography (MLC) with absorbance detection. This technique
was chosen because it allows the direct injection of biological samples without any
previous treatment. This fact is an advantage over other analytical techniques reviewed
in the literature, which are more expensive and require more longer and complex
experimental procedures. Another important advantage is the use of mobile phases of
high water content in isocratic mode, compared to the conventional RP-HPLC that uses
hydro-organic mobile phases circulating in gradient. This fact results in less time for
analysis and less use of toxic organic solvents. [-]
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Descripción
Treball Final de Grau en Química. Codi: QU0943. Curs acadèmic: 2018/2019
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info:eu-repo/semantics/bachelorThesisDerechos de acceso
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- Grau en Química [265]