Supramolecular protection from the enzymatic tyrosine phosphorylation in a polypeptide
Ver/ Abrir
Impacto
Scholar |
Otros documentos de la autoría: Faggi, Enrico; Pérez, Yolanda; Luis, Santiago V.; Alfonso Rodríguez, Ignacio
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
comunitat-uji-handle4:
INVESTIGACIONMetadatos
Título
Supramolecular protection from the enzymatic tyrosine phosphorylation in a polypeptideFecha de publicación
2016-05Editor
Royal Society of ChemistryCita bibliográfica
Faggi, E., Pérez, Y., Luis, S. V., & Alfonso, I. (2016). Supramolecular protection from the enzymatic tyrosine phosphorylation in a polypeptide. Chemical Communications.Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://pubs.rsc.org/en/content/articlelanding/2016/cc/c6cc03875a#!divAbstractPalabras clave / Materias
Resumen
Here we report two new artificial pseudopeptidic cages that bind the EYE peptide epitope in pure water at physiological pH (as studied by fluorescence and NMR spectroscopies). The supramolecular complexation of the ... [+]
Here we report two new artificial pseudopeptidic cages that bind the EYE peptide epitope in pure water at physiological pH (as studied by fluorescence and NMR spectroscopies). The supramolecular complexation of the Tyr residues efficiently precludes their subsequent PTK-catalysed phosphorylation. Our results show a supramolecular modulation of the PTK activity by competitive substrate caging. [-]
Publicado en
Chemical Communications, 2016, Advanced ArticleDerechos de acceso
© The Royal Society of Chemistry 2016
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Aparece en las colecciones
- QUIO_Articles [702]
El ítem tiene asociados los siguientes ficheros de licencia: