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The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
(Elsevier, 2019-02-01)
It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...
Osseointegration mechanisms: a proteomic approach
(Springer-Verlag, 2018-03)
The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration
and to short the time needed to achieve it. Design of implants nowadays involves changes in ...
Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
(Elsevier, 2020-12-30)
Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...
Characterization of serum proteins attached to distinct sol–gel hybrid surfaces
(Wiley, 2017-07)
The success of a dental implant depends on its osseointegration, an important feature of the implant biocompatibility. In this study, two distinct sol–gel hybrid coating formulations [50% methyltrimethoxysilane: 50% ...
Complement proteins regulating macrophage polarisation on biomaterials
(Elsevier, 2019-09-01)
One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ...
Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico
(Ediciones Peldaño, 2017-12)
Titanium is a biomaterial largely used on dental implant
manufacturing. However, as a consequence of its
intrinsically low bioactivity, the development of distinct
superficial treatments in order to enhance its ...
Proteomic evaluation of human osteoblast responses to titanium implants over time
(WileyWiley Periodicals, 2022-08-30)
Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo
(Taylor & Francis, 2017)
The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ...
A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
(Elsevier, 2020)
Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ...
Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications
(Wiley, 2018-05)
Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration ...