Listar FCA_Articles por autoría "ec70e01d-cd8e-4070-a2f3-67d9249e98d1"
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Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge
Verdiá Báguena, Carmen; Nieto Torres, José L.; Alcaraz, Antonio; De Diego, Marta L.; Enjuanes, Luis; Aguilella, Vicente Elsevier (2013-05-18)A partial characterization of the ion channels formed by the SARS coronavirus (CoV) envelope (E) protein was previously reported (C. Verdiá-Báguena et al., 2012 [12]). Here, we provide new significant insights on the ... -
Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids
Aguilella, Vicente; Alcaraz, Antonio; Verdiá Báguena, Carmen; Nieto Torres, José L.; De Diego, Marta L.; Torres, Jaume; Enjuanes, Luis Elsevier (2012-10)Coronavirus (CoV) envelope (E) protein ion channel activity was determined in channels formed in planar lipid bilayers by peptides representing either the transmembrane domain of severe acute respiratory syndrome CoV ... -
Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis
Castaño Rodríguez, Carlos; Honrubia, José M.; Gutiérrez-Álvarez, Javier; De Diego, Marta L.; Nieto Torres, José L.; Jiménez Guardeño, José M.; Regla Nava, José A.; Fernández Delgado, Raúl; Verdiá Báguena, Carmen; Queralt-Martín, María; Kochan, Grazyna; Perlman, Stanley; Aguilella, Vicente; Sola, Isabel; Enjuanes, Luis American Society for Microbiology (2018)Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis. While many coronaviruses (CoVs) encode two viroporins, severe ... -
Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis
Nieto Torres, José L.; De Diego, Marta L.; Verdiá Báguena, Carmen; Jiménez Guardeño, José M.; Regla Nava, José A.; Fernández Delgado, Raúl; Castaño Rodríguez, Carlos; Alcaraz, Antonio; Torres, Jaume; Aguilella, Vicente; Enjuanes, Luis Public Library of Science (2014)Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E) gene attenuates the virus. E gene encodes a small multifunctional protein that possesses ion channel (IC) activity, an important function ...