Listar por tema "Inhibition"
Mostrando ítems 1-8 de 8
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Computational Studies of the Mechanism of Catalysis and Inhibition of Cysteine Proteases
Universitat Jaume I (2017-09-27)Falcipain-2 and cruzain are cysteine proteases involve in Malaria and Chagas disease. Today, many aspects of both, inhibition mechanism and catalytic mechanism of these enzymes are unclear. Thus, it is crucial to improve ... -
Computational Study on the Reactivity and Inhibition of Arginine Gingipain B, a Potential Target for the Treatment of Alzheimer's Disease
Universitat Jaume I (2023-01-27)Since its identification in 1901, by the German psychiatrist Alois Alzheimer, Alzheimer's disease has emerged as one of the greatest challenges in pharmaceutical research. In 2019, the cysteine protease RgpB was identified ... -
Funcionamiento ejecutivo cognitivo y conductual: marcadores del rendimiento inicial en cálculo en Educación Infantil.
Universitat Jaume I (2019-10-21)This study analyses the association between executive functioning factors of working memory and inhibition with initial performance in arithmetic. Analyses are performed in a sample of 208 children (aged 5 and 6) assessed ... -
Funcionamiento ejecutivo y motivación en niños de educación infantil con riesgo de dificultades en el aprendizaje de las matemáticas
Viguera (2015)Introduccion. Los avances en las tecnicas de neuroimagen han propiciado un creciente interes por el estudio del cerebelo y su participacion en los procesos cognitivos. Es cada vez mas evidente la relacion que existe entre ... -
Funciones ejecutivas y características estresantes de niños con trastorno por déficit de atención/hiperactividad: influencia en los resultados durante la adolescencia
Viguera (2012)The identification of possible factors that are influencing the course of attention-deficit hyperactivity disorder (ADHD) will allow the development of more effective early intervention strategies. This research, which ... -
Mitochondrial (dys)function-a factor underlying the variability of EFV-induced hepatoxicity?
Wiley (2015-01-08)Background and PurposeThe non-nucleoside analogue reverse transcriptase inhibitor efavirenz is associated with hepatic toxicity and metabolic disturbances. Although the mechanisms involved are not clear, recent evidence ... -
QM/MM Calculations Suggest a Novel Intermediate Following the Proton Abstraction Catalyzed by Thymidylate Synthase
American Chemical Society (2013-03-07)The cleavage of covalent C–H bonds is one of the most energetically demanding, yet biologically essential, chemical transformations. Two C–H bond cleavages are involved in the reaction catalyzed by thymidylate synthase ... -
¿Qué papel desempeñan la memoria de trabajo y la inhibición en la resolución de problemas matemáticos? Evaluación neuropsicológica y ecológica en preescolar.
Universitat Jaume I (2019-10-21)This paper analyzes the role of working memory and inhibition, evaluated with ecological and neuropsychological tests, on performance and initial difficulties in solving mathematical problems in preschool students. The ...