Listar por tema "Adenosine"
Mostrando ítems 1-5 de 5
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Adenosine A(2A) and A(2B) Receptors Differentially Modulate Keratinocyte Proliferation: Possible Deregulation in Psoriatic Epidermis
Elsevier (2017-01)Adenosine is a potent regulator of inflammation and immunity, but the role of adenosine receptors in keratinocytes remains controversial. We determined that in addition to A2B receptors, human epidermal keratinocytes also ... -
Dopamine depletion shifts behavior from activity based reinforcers tomore sedentary ones and adenosine receptor antagonism reversesthat shift: Relation to ventral striatum DARPP32 phosphorylationpatterns
Elsevier (2018)The mesolimbic dopamine (DA) system plays a critical role in behavioral activation and effort-baseddecision-making. DA depletion produces anergia (shifts to low effort options) in animals tested oneffort-based decision-making ... -
Involvement of adenosinergic and dopaminergic systems in the regulation of alcohol or sucrose intake: studies in rodent models of self-administration
Universitat Jaume I (2017-07-18)Caffeine is a methylxanthine that acts as a nonselective adenosine antagonist, binding to adenosine A1 and A2A receptor subtypes. This substance is highly present in different beverages like coffee, tea and in energy drinks. ... -
Role of dopamine–adenosine interactions in the brain circuitry regulating effort-related decision making: insights into pathological aspects of motivation
Future Medicine (2010)Brain dopamine, particularly in the nucleus accumbens, has been implicated in activational aspects of motivation and effort-related processes. Accumbens dopamine depletions reduce the tendency of rats to work for food, and ... -
The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences
Elsevier (2016)This review paper is focused upon the involvement of mesolimbic dopamine (DA) and related brain systems in effort-based processes. Interference with DA transmission affects instrumental behavior in a manner that interacts ...