• openAccess   Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses 

      Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Iloro, Ibon; Azkargorta, Mikel; Elortza, Felix; Izquierdo Escrig, Raul; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2020-12-30)
      Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...
    • openAccess   Characterization of serum proteins attached to distinct sol–gel hybrid surfaces 

      Gomes, Nuno; Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; GURRUCHAGA, MARILO; Azkargorta, Mikel; Elortza, Felix; Ibáñez, Maria; Iloro, Ibon; Suay, Julio; Goñi, Isabel Wiley (2017-07)
      The success of a dental implant depends on its osseointegration, an important feature of the implant biocompatibility. In this study, two distinct sol–gel hybrid coating formulations [50% methyltrimethoxysilane: 50% ...
    • openAccess   Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes 

      García-Arnáez, Iñaki; Cerqueira, Andreia; Romero-Gavilán, Francisco J; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; Suay, Julio; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2022)
      Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of osteoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ...
    • openAccess   Proteome analysis of human serum proteins adsorbed onto different titanium surfaces used in dental implants 

      Romero-Gavilán, Francisco J; Gomes, N. C.; Ródenas, Joaquin; Sánchez, Ana; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; García-Arnáez, Iñaki; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)
      Titanium dental implants are commonly used due to their biocompatibility and biochemical properties; blasted acid-etched Ti is used more frequently than smooth Ti surfaces. In this study, physico-chemical characterisation ...
    • openAccess   Proteomic analysis of calcium-enriched sol–gel biomaterials 

      Romero-Gavilán, Francisco J; Gomes, Nuno; Cerqueira, Andreia; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Springer (2019-04)
      Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ...
    • openAccess   Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo 

      Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; Gomes, Nuno; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; Gurruchaga, Marilo; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)
      The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ...
    • openAccess   The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions 

      Romero-Gavilán, Francisco J; Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2019-02-01)
      It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...