• openAccess   Changes in drug use in European cities during early COVID-19 lockdowns ? A snapshot from wastewater analysis 

      Been, Frederic; Emke, Erik; Matias, Joao Luis; Baz Lomba, Jose Antonio; Boogaerts, Tim; Castiglioni, Sara; Campos-Mañas, Marina Celia; Celma, Alberto; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; ter Laak, Thomas; Reid, Malcolm; Salgueiro-González, Noelia; Steenbeek, Ruud; van Nuijs, Alexander; Zuccato, Ettore; Bijlsma, Lubertus Elsevier (2021-03-26)
      The COVID-19 outbreak has forced countries to introduce severe restrictive measures to contain its spread. In particular, physical distancing and restriction of movement have had important consequences on human behaviour ...
    • openAccess   Drug use by music festival attendees: A novel triangulation approach using self-reported data and test results of oral fluid and pooled urine samples 

      Gjerde, Hallvard; Gjersing, Linn; Baz Lomba, Jose Antonio; Bijlsma, Lubertus; Salgueiro-González, Noelia; Furuhaugen, Havard; Bretteville-Jensen, Anne LIne; Hernandez, Felix; Castiglioni, Sara; Amundsen, Ellen Johanna; Zuccato, Ettore Taylor & Francis (2019)
      Background: Self-reported data are commonly used when investigating illicit substance use. However, self-reports have well-known limitations such as limited recall and socially desirable responding. Mislabeling or ...
    • closedAccess   Enantiomeric profiling of quinolones and quinolones resistance gene qnrS in European wastewaters 

      Castrignano', Erika; Yang, Zhugen; Feil, Edward; Bade, Richard; Castiglioni, Sara; Causanilles, Ana; GRACIA LOR, EMMA; Hernandez, Felix; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2020)
      Wastewater-based epidemiology (WBE) was applied for the first time in seven cities across Europe with the aim of estimating quinolones consumption via the analysis of human urinary metabolites in wastewater. This report ...
    • closedAccess   Enantiomeric profiling of chiral illicit drugs in a pan-European study 

      Castrignanò, Erika; Yang, Zhugen; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Causanilles, Ana; Covaci, Adrian; GRACIA LOR, EMMA; Hernandez, Felix; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2018)
      The aim of this paper is to present the first study on spatial and temporal variation in the enantiomeric profile of chiral drugs in eight European cities. Wastewater-based epidemiology (WBE) and enantioselective analysis ...
    • openAccess   Estimation of caffeine intake from analysis of caffeine metabolites in wastewater 

      GRACIA LOR, EMMA; Rousis, Nikolaos I; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Santos, Miguel M.; Thomas, Kevin V.; de Voogt, Pim; Yang, Zhugen; Castiglioni, Sara Elsevier (2017-12)
      Caffeine metabolites in wastewater were investigated as potential biomarkers for assessing caffeine intake in a population. The main human urinary metabolites of caffeine were measured in the urban wastewater of ten European ...
    • closedAccess   Evaluation of Uncertainties Associated with the Determination of Community Drug Use through the Measurement of Sewage Drug Biomarkers 

      Castiglioni, Sara; Bijlsma, Lubertus; Covaci, Adrian; Emke, Erik; Hernandez, Felix; Reid, Malcolm; Ort, Christoph; Thomas, Kevin V.; van Nuijs, Alexander; de Voogt, Pim; Zuccato, Ettore American Chemical Society (2013)
      The aim of this study was to integrally address the uncertainty associated with all the steps used to estimate community drug consumption through the chemical analysis of sewage biomarkers of illicit drugs. Uncertainty has ...
    • openAccess   Flexible high resolution-mass spectrometry approach for screening new psychoactive substances in urban wastewater 

      Salgueiro-González, Noelia; Castiglioni, Sara; GRACIA LOR, EMMA; Bijlsma, Lubertus; Celma, Alberto; Bagnati, Renzo; Hernandez, Felix; Zuccato, Ettore Elsevier (2019-11-01)
      The number of new psychoactive substances (NPS) on the recreational drug market has increased rapidly in the last years, creating serious challenges for public health agencies and law enforcement authorities. Epidemiological ...
    • closedAccess   International snapshot of new psychoactive substance use: Case study of eight countries over the 2019/2020 new year period 

      Bade, Richard; White, Jason M.; Chen, Jingjing; Baz Lomba, Jose Antonio; Been, Frederic; Bijlsma, Lubertus; Universitat Jaume I. Departament de Química Física i Analítica; Burgard, Daniel A.; Castiglioni, Sara; Salgueiro-González, Noelia; Celma, Alberto; Universitat Jaume I. Departament de Química Física i Analítica; Chappell, Andrew; Emke, Erik; Steenbeek, Ruud; Wang, Degao; Zuccato, Ettore; Gerber, Cobus Elsevier (2021-02-03)
      There is considerable concern around the use of new psychoactive substances (NPS), but still little is known about how much they are really consumed. Analysis by forensics laboratories of seized drugs and post-mortem samples ...
    • openAccess   Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities 

      Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017)
      The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ...
    • openAccess   Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities 

      Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017-02)
      The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ...
    • openAccess   Mass spectrometric strategies for the investigation of biomarkers of illicit drug use in wastewater 

      Hernandez, Felix; Castiglioni, Sara; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Kasprzyk-Hordern, Barbara; Ort, Christoph; Reid, Malcolm; Vicente Sancho, Juan; Thomas, Kevin V.; van Nuijs, Alexander; Zuccato, Ettore; Bijlsma, Lubertus Wiley (2018)
      The analysis of illicit drugs in urban wastewater is the basis of wastewater‐based epidemiology (WBE), and has received much scientific attention because the concentrations measured can be used as a new non‐intrusive tool ...
    • openAccess   Measuring biomarkers in wastewater as a new source of epidemiological information: current state and future perspectives 

      GRACIA LOR, EMMA; Castiglioni, Sara; Bade, Richard; Been, Frederic; Castrignanò, Erika; Covaci, Adrian; González-Mariño, Iria; Hapeshi, Evroula; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; Lai, Foon Yin; Letzel, Thomas; Lopardo, Luigi; Meyer, Markus R.; O'Brien, Jake; Ramin, Pedram; Rousis, Nikolaos I; Rydevik, Axel; Ryu, Yeonsuk; Santos, Miguel M.; Senta, Ivan; Thomaidis, Nikolaos; Veloutsou, Sofia; Yang, Zhugen; Zuccato, Ettore; Bijlsma, Lubertus Elsevier (2017-02)
      The information obtained from the chemical analysis of specific human excretion products (biomarkers) in urban wastewater can be used to estimate the exposure or consumption of the population under investigation to a defined ...
    • openAccess   Monitoring a large number of pesticides and transformation products in water samples from Spain and Italy 

      Rousis, Nikolaos I; Bade, Richard; Bijlsma, Lubertus; Zuccato, Ettore; Sancho, Juan V; Hernandez, Felix; Castiglioni, Sara Elsevier (2017-07)
      Assessing the presence of pesticides in environmental waters is particularly challenging because of the huge number of substances used which may end up in the environment. Furthermore, the occurrence of pesticide transformation ...
    • openAccess   Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis 

      Bijlsma, Lubertus; Celma, Alberto; Castiglioni, Sara; Salgueiro-González, Noelia; Bou Iserte, Lledó; Baz Lomba, Jose Antonio; Reid, Malcolm; Dias, M.J.; Lopes, Alvaro; Matias, Joao Luis; Pastor Alcañiz, Laura; Radonic, J.; Turk Sekulic, M.; Shine, Trevor; van Nuijs, Alexander; Hernandez, Felix; Zuccato, Ettore Elsevier (2020-07-10)
      The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily ...
    • closedAccess   New psychoactive substances in several European populations assessed by wastewater-based epidemiology 

      Castiglioni, Sara; Salgueiro-González, Noelia; Bijlsma, Lubertus; Celma, Alberto; GRACIA LOR, EMMA; Beldean-Galea, Mihail Simion; Mackuľak, Tomáš; Emke, Erik; Heath, Ester; Kasprzyk-Hordern, Barbara; Kovacevic, Andjelka; Poretti, Francesco; Rangelov, Jeliaz; Santos, Miguel M.; Sremački, Maja; Hernandez, Felix; Zuccato, Ettore Elsevier (2021)
      Wastewater-based epidemiology (WBE) can be a useful tool to face some of the existing challenges in monitoring the use of new psychoactive substances (NPS), as it can provide objective and updated infor- mation. This ...
    • openAccess   Simultaneous determination of new psychoactive substances and illicit drugs in sewage: Potential of micro-liquid chromatography tandem mass spectrometry in wastewater-based epidemiology 

      Celma, Alberto; Sancho, Juan V; Salgueiro-González, Noelia; Castiglioni, Sara; Zuccato, Ettore; Hernandez, Felix; Bijlsma, Lubertus Elsevier (2019-05-30)
      Wastewater-based epidemiology (WBE) can give valuable light on the extent and actual use of new psychoactive substances (NPS). In this work, a fully validated methodology for the simultaneous determination of illicit drugs ...
    • openAccess   Spatio‐temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring 

      González-Mariño, Iria; Baz Lomba, Jose Antonio; Alygizakis, Nikiforos; Andrés-Costa, Maria Jesús; Bade, Richard; Bannwarth, Anne; Barron, Leon; Been, Frederic; Benaglia, Lisa; Berset, Jean-Daniel; Bijlsma, Lubertus; Bodík, Igor; Brenner, Asher; Brock, Andreas L.; Burgard, Daniel A.; Castrignanò, Erika; Celma, Alberto; Christophoridis, Christophoros; Covaci, Adrian; Delémont, Olivier; de Voogt, Pim; Devault, Damien A.; Mário J. Dias, Mário J.; Emke, Erik; Esseiva, Pierre; Fatta-Kassinos, Despo; Fedorova, Ganna; Fytianos, Konstantinos; Gerber, Cobus; Grabic, Roman; GRACIA LOR, EMMA; Grüner, Stefan; Gunnar, Teemu; Hapeshi, Evroula; Heath, Ester; Helm, Björn; Hernandez, Felix; Kankaanpaa, Aino; Kasprzyk-Hordern, Barbara; Krizman-Matasic, Ivona; Lai, Foon Yin; Lechowicz, Wojciech; Lopes, Alvaro; López de Alda, Miren; López-García, Ester; Löve, Arndís; Mastroianni, Nicola; McEneff, Gillian; Montes, Rosa; Munro, Kelly; Nefau, Thomas; Oberacher, Herbert; O'Brien, Jake William; Oertel, Reinhard; Olafsdottir, Kristin; Picó, Yolanda; Plosz, Benedek; Polesel, Fabio; Postigo, Cristina; Quintana, José Benito; Ramin Pedram; Reid, Malcolm J.; Rice, Jack; Rodil, Rosario; Salgueiro-González, Noelia; Schubert, Sara; Senta, Ivan; Simões, Susana M.; Sremački, Maja; Styszko, Katarzyna; Terzic, Senka; Thomaidis, Nikolaos; Thomas, Kevin V.; Tscharke, Ben J.; Udrisard, Robin; van Nuijs, Alexander; Yargeau Viviane; Zuccato, Ettore; Castiglioni, Sara; Ort, Christoph Wiley (2020-01)
      Background and aims: Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess ...
    • openAccess   Three years of wastewater surveillance for new psychoactive substances from 16 countries 

      Bade, Richard; Rousis, Nikolaos I; Adhikari, Sangeet; Baduel, Christine; Bijlsma, Lubertus; Bizani, Erasmia; Boogaerts, Tim; Burgard, Daniel A.; Castiglioni, Sara; Chappell, Andrew; Covaci, Adrian; Driver, Erin M.; Fabriz Sodré, Fernando; Fatta-Kassinos, Despo; Galani, Aikaterini; Gerber, Cobus; GRACIA LOR, EMMA; Gracia-Marín, Elisa; Halden, Rolf; Heath, Ester; Hernandez, Felix; Yin Lai, Foon; Lee, Heon-Jun; Laimou-Geraniou, Maria; Oh, Jeong-Eun; Olafsdottir, Kristin; Phung, Kaitlyn; Pineda Castro, Marco; Psichoudaki, Magda; Shao, Xueting; Salgueiro-González, Noelia; Silva Feitosa, Rafael; Silvino Gomes, Cezar; Subedi, Bikram; Löve, Arndís; Thomaidis, Nikolaos; Tran, Diana; van Nuijs, Alexander; Verovšek, Taja; Wang, Degao; White, Jason; Yargeau, Viviane; Zuccato, Ettore; Mueller, Jochen Elsevier (2023-05)
      The proliferation of new psychoactive substances (NPS) over recent years has made their surveillance complex. The analysis of raw municipal influent wastewater can allow a broader insight into community consumption patterns ...
    • closedAccess   Wastewater-Based Epidemiology as a Novel Biomonitoring Tool to Evaluate Human Exposure To Pollutants 

      GRACIA LOR, EMMA; Rousis, Nikolaos I; Hernandez, Felix; Zuccato, Ettore; Castiglioni, Sara ACS (2018-08-27)
      Humans are continuously exposed to pollutants by different routes, and human biomonitoring (HBM) is the tool commonly used to assess exposure to chemicals by measuring parent substances or metabolites in human specimens. ...
    • closedAccess   Wastewater-based epidemiology as a novel tool to evaluate human exposure to pesticides: Triazines and organophosphates as case studies 

      Rousis, Nikolaos I; GRACIA LOR, EMMA; Hernandez, Felix; Poretti, Francesco; Santos, Miguel M.; Zuccato, Ettore; Castiglioni, Sara Elsevier ScienceDirect (2021-06-22)
      Production and application of pesticides have risen remarkably in the last few decades. Even if they provide many benefits, they can be hazardous for humans and ecosystems when they are not used cautiously. Human exposure ...