Listar por autoría "29119e62-33bf-457c-bf75-8dfbaba9c46e"
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Bioactive potential of silica coatings and its effect on the adhesion of proteins to titanium implants
Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J.J.; Carda, C.; Gurruchaga, Marilo; Suay, Julio; Goñi, Isabel Elsevier (2018-02-01)There is an ever-increasing need to develop dental implants with ideal characteristics to achieve specific and desired biological response in the scope of improve the healing process post-implantation. Following that ... -
Characterization of serum proteins attached to distinct sol–gel hybrid surfaces
Gomes, Nuno; Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; GURRUCHAGA, MARILO; Azkargorta, Mikel; Elortza, Felix; Ibáñez, Maria; Iloro, Ibon; Suay, Julio; Goñi, Isabel Wiley (2017-07)The success of a dental implant depends on its osseointegration, an important feature of the implant biocompatibility. In this study, two distinct sol–gel hybrid coating formulations [50% methyltrimethoxysilane: 50% ... -
Complement proteins regulating macrophage polarisation on biomaterials
Gomes, Nuno; Romero-Gavilán, Francisco J; Zhang, Yiyue; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; van den Beucken, J.J.J.P.; Suay, Julio Elsevier (2019-09-01)One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ... -
Osseointegration mechanisms: a proteomic approach
Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ... -
Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico
Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Ediciones Peldaño (2017-12)Titanium is a biomaterial largely used on dental implant manufacturing. However, as a consequence of its intrinsically low bioactivity, the development of distinct superficial treatments in order to enhance its ... -
Proteomic analysis of calcium-enriched sol–gel biomaterials
Romero-Gavilán, Francisco J; Gomes, Nuno; Cerqueira, Andreia; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Springer (2019-04)Calcium is an element widely used in the development of biomaterials for bone tissue engineering as it plays important roles in bone metabolism and blood coagulation. The Ca ions can condition the microenvironment at the ... -
Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo
Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; Gomes, Nuno; Azkargorta, Mikel; Iloro, Ibon; Elortza, Felix; Gurruchaga, Marilo; Goñi, Isabel; Suay, Julio Taylor & Francis (2017)The interactions of implanted biomaterials with the host organism determine the success or failure of an implantation. Normally, their biocompatibility is assessed using in vitro tests. Unfortunately, in vitro and in vivo ... -
Silica-gelatin hybrid sol-gel coatings: A proteomic study with biocompatibility implications
Gomes, Nuno; Romero-Gavilán, Francisco J; Lara, Irene; Elortza, Felix; Azkargorta, Mikel; Lloro, Ibon; Ibáñez, Maria; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Sánchez-Pérez, Ana María Wiley (2018-05)Osseointegration, including the foreign body reaction to biomaterials, is an immune‐modulated, multifactorial, and complex healing process in which various cells and mediators are involved. The buildup of the osseointegration ... -
Synthesis and characterization of silica-chitosan hybrid materials as antibacterial coatings for titanium implants
Palla-Rubio, B.; Gomes, Nuno; Fernández Gutiérrez, Mar; Rojo, Luis; Suay, Julio; Gurruchaga, Mariló; Goñi, Isabel Elsevier (2019-01)To avoid dental implant-related infections and to promote the osseointegration of titanium implants, the application of silicon and chitosan containing coatings is proposed. Silicon is a well-known osteogenic element and ... -
The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
Romero-Gavilán, Francisco J; Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2019-02-01)It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...