• openAccess   Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis 

      Bijlsma, Lubertus; Celma, Alberto; Castiglioni, Sara; Salgueiro-González, Noelia; Bou Iserte, Lledó; Baz Lomba, Jose Antonio; Reid, Malcolm; Dias, M.J.; Lopes, Alvaro; Matias, Joao Luis; Pastor Alcañiz, Laura; Radonic, J.; Turk Sekulic, M.; Shine, Trevor; van Nuijs, Alexander; Hernandez, Felix; Zuccato, Ettore Elsevier (2020-07-10)
      The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily ...
    • openAccess   Multi-year interlaboratory exercises for the analysis of illicit drugs and metabolites in wastewater: development of a quality control system 

      van Nuijs, Alexander; Lai, Foon Yin; Been, Frederic; Andrés-Costa, Maria Jesús; Barron, León P.; Baz Lomba, Jose Antonio; Berset, Jean-Daniel; Benaglia, Lisa; Bijlsma, Lubertus; Burgard, Daniel A.; Castiglioni, Sara; Christophoridis, Christophoros; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Fatta-Kassinos, Despo; Fick, Jerker; Hernandez, Felix; Gerber, Cobus; González-Marino, Iria; Grabic, Roman; Gunnar, Teemu; Kannan, Kurunthachalam; Karolak, Sara; Kasprzyk-Hordern, Barbara; Kokot, Zenon; Krizman-Matasic, Ivona; Li, Angela; Li, Xiqing; Love, Arndis S. C.; López de Alda, Miren; McCall, Ann Kathrin; Meyer, Markus R.; Oberacher, Herbert; O'Brien, Jake; Quintana, José B.; Reid, Malcolm; Schneider, Serge; Sadler Simoes, Susana; Thomaidis, Nikolaos; Thomas, Kevin; Yargeau, Viviane; Ort, Christoph Elsevier (2018)
      This study presents the development of a worldwide inter-laboratory testing scheme for the analysis of seven illicit drug residues in different matrices (standard solutions, tap- and wastewater). By repeating this exercise ...
    • closedAccess   New psychoactive substances in several European populations assessed by wastewater-based epidemiology 

      Castiglioni, Sara; Salgueiro-González, Noelia; Bijlsma, Lubertus; Celma, Alberto; GRACIA LOR, EMMA; Beldean-Galea, Mihail Simion; Mackuľak, Tomáš; Emke, Erik; Heath, Ester; Kasprzyk-Hordern, Barbara; Kovacevic, Andjelka; Poretti, Francesco; Rangelov, Jeliaz; Santos, Miguel M.; Sremački, Maja; Hernandez, Felix; Zuccato, Ettore Elsevier (2021)
      Wastewater-based epidemiology (WBE) can be a useful tool to face some of the existing challenges in monitoring the use of new psychoactive substances (NPS), as it can provide objective and updated infor- mation. This ...
    • openAccess   One planet: one health. A call to support the initiative on a global science–policy body on chemicals and waste 

      Brack, Werner; Barcelo Culleres, Damia; Boxall, Alistair Bruce Alleyne; Budzinsk, Hélène; Castiglioni, Sara; Covaci, Adrian; Hernandez, Felix SpringerOpen (2022-03-08)
      The chemical pollution crisis severely threatens human and environmental health globally. To tackle this challenge the establishment of an overarching international science–policy body has recently been suggested. We ...
    • openAccess   Perspectives and challenges associated with the determination of new psychoactive substances in urine and wastewater – A tutorial 

      Bijlsma, Lubertus; Bade, Richard; Been, Frederic; Celma, Alberto; Castiglioni, Sara Elsevier (2021-02-08)
      New psychoactive substances (NPS), often designed as (legal) substitutes to conventional illicit drugs, are constantly emerging in the drug market and being commercialized in different ways and forms. Their use continues ...
    • openAccess   Screening of Pharmaceuticals and Illicit Drugs in Wastewater and Surface Waters of Spain and Italy by High Resolution Mass Spectrometry using UHPLC-QTOF MS and LC-LTQ-Orbitrap MS 

      Bade, Richard; Rousis, Nikolaos I; Bijlsma, Lubertus; GRACIA LOR, EMMA; Castiglioni, Sara; Sancho, Juan V; Hernandez, Felix Springer (2015)
      The existence of pharmaceuticals and illicit drugs (PIDs) in environmental waters has led many analytical chemists to develop screening methods for monitoring purposes. Water samples can contain a huge number of possible ...
    • openAccess   Sewage-based Epidemiology Requires a Truly Transdisciplinary Approach 

      Ort, Christoph; Banta-Green, Caleb J.; Bijlsma, Lubertus; Castiglioni, Sara; Emke, Erik; Gartner, Coral; Kasprzyk-Hordern, Barbara; Reid, Malcolm; Rieckermann, Jörg; van Nuijs, Alexander oekom verlag (2014)
      If asked whether you had consumed illicit drugs recently, would you admit it? If yes, could you precisely recall types of drug, times and amounts used? If you were the person commissioned with the task of quantifying drug ...
    • openAccess   Simultaneous determination of new psychoactive substances and illicit drugs in sewage: Potential of micro-liquid chromatography tandem mass spectrometry in wastewater-based epidemiology 

      Celma, Alberto; Sancho, Juan V; Salgueiro-González, Noelia; Castiglioni, Sara; Zuccato, Ettore; Hernandez, Felix; Bijlsma, Lubertus Elsevier (2019-05-30)
      Wastewater-based epidemiology (WBE) can give valuable light on the extent and actual use of new psychoactive substances (NPS). In this work, a fully validated methodology for the simultaneous determination of illicit drugs ...
    • closedAccess   Spatial and temporal assessment of crack cocaine use in 13 European cities through wastewater-based epidemiology 

      Steenbeek, Ruud; Emke, Erik; Vughs, Dennis; Matias, Joao Luis; Boogaerts, Tim; Castiglioni, Sara; Campos-Mañas, Marina Celia; Covaci, Adrian; de Voogt, Pim; ter Laak, Thomas; Hernandez, Felix; Salgueiro-González, Noelia; Meijer, Wim; Dias, Mario J.; Simoes, Susana; van Nuijs, Alexander; Bijlsma, Lubertus; Been, Frederic Elsevier (2022-07-25)
      Already in early 2000s, concerns have been growing in the EU about increasing use of cocaine and it is estimated that below 1% of the population administer the drug by smoking crack cocaine. New available data suggests ...
    • openAccess   Spatial differences and temporal changes in illicit drug use in Europe quantified by wastewater analysis 

      Ort, Christoph; van Nuijs, Alexander; Berset, Jean-Daniel; Bijlsma, Lubertus; Castiglioni, Sara; Covaci, Adrian; de Voogt, Pim; Emke, Erik; Fatta-Kassinos, Despo; Griffiths, Paul; Hernandez, Felix; González-Mariño, Iria; Grabic, Roman; Kasprzyk-Hordern, Barbara; Mastroianni, Nicola; Meierjohann, Axel; Nefau, Thomas; Östman, Marcus; Picó Gracia, Yolanda; Racamonde, Inés; Reid, Malcolm; Slobodnik, Jaroslav; Terzic, Senka; Thomaidis, Nikolaos; Thomas, Kevin V. Wiley (2014-08)
      Aims To perform wastewater analyses to assess spatial differences and temporal changes of illicit drug use in a large European population. Design Analyses of raw wastewater over a 1-week period in 2012 and 2013. Setting ...
    • openAccess   Spatio‐temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring 

      González-Mariño, Iria; Baz Lomba, Jose Antonio; Alygizakis, Nikiforos; Andrés-Costa, Maria Jesús; Bade, Richard; Bannwarth, Anne; Barron, Leon; Been, Frederic; Benaglia, Lisa; Berset, Jean-Daniel; Bijlsma, Lubertus; Bodík, Igor; Brenner, Asher; Brock, Andreas L.; Burgard, Daniel A.; Castrignanò, Erika; Celma, Alberto; Christophoridis, Christophoros; Covaci, Adrian; Delémont, Olivier; de Voogt, Pim; Devault, Damien A.; Mário J. Dias, Mário J.; Emke, Erik; Esseiva, Pierre; Fatta-Kassinos, Despo; Fedorova, Ganna; Fytianos, Konstantinos; Gerber, Cobus; Grabic, Roman; GRACIA LOR, EMMA; Grüner, Stefan; Gunnar, Teemu; Hapeshi, Evroula; Heath, Ester; Helm, Björn; Hernandez, Felix; Kankaanpaa, Aino; Kasprzyk-Hordern, Barbara; Krizman-Matasic, Ivona; Lai, Foon Yin; Lechowicz, Wojciech; Lopes, Alvaro; López de Alda, Miren; López-García, Ester; Löve, Arndís; Mastroianni, Nicola; McEneff, Gillian; Montes, Rosa; Munro, Kelly; Nefau, Thomas; Oberacher, Herbert; O'Brien, Jake William; Oertel, Reinhard; Olafsdottir, Kristin; Picó, Yolanda; Plosz, Benedek; Polesel, Fabio; Postigo, Cristina; Quintana, José Benito; Ramin Pedram; Reid, Malcolm J.; Rice, Jack; Rodil, Rosario; Salgueiro-González, Noelia; Schubert, Sara; Senta, Ivan; Simões, Susana M.; Sremački, Maja; Styszko, Katarzyna; Terzic, Senka; Thomaidis, Nikolaos; Thomas, Kevin V.; Tscharke, Ben J.; Udrisard, Robin; van Nuijs, Alexander; Yargeau Viviane; Zuccato, Ettore; Castiglioni, Sara; Ort, Christoph Wiley (2020-01)
      Background and aims: Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess ...
    • openAccess   Three years of wastewater surveillance for new psychoactive substances from 16 countries 

      Bade, Richard; Rousis, Nikolaos I; Adhikari, Sangeet; Baduel, Christine; Bijlsma, Lubertus; Bizani, Erasmia; Boogaerts, Tim; Burgard, Daniel A.; Castiglioni, Sara; Chappell, Andrew; Covaci, Adrian; Driver, Erin M.; Fabriz Sodré, Fernando; Fatta-Kassinos, Despo; Galani, Aikaterini; Gerber, Cobus; GRACIA LOR, EMMA; Gracia-Marín, Elisa; Halden, Rolf; Heath, Ester; Hernandez, Felix; Yin Lai, Foon; Lee, Heon-Jun; Laimou-Geraniou, Maria; Oh, Jeong-Eun; Olafsdottir, Kristin; Phung, Kaitlyn; Pineda Castro, Marco; Psichoudaki, Magda; Shao, Xueting; Salgueiro-González, Noelia; Silva Feitosa, Rafael; Silvino Gomes, Cezar; Subedi, Bikram; Löve, Arndís; Thomaidis, Nikolaos; Tran, Diana; van Nuijs, Alexander; Verovšek, Taja; Wang, Degao; White, Jason; Yargeau, Viviane; Zuccato, Ettore; Mueller, Jochen Elsevier (2023-05)
      The proliferation of new psychoactive substances (NPS) over recent years has made their surveillance complex. The analysis of raw municipal influent wastewater can allow a broader insight into community consumption patterns ...
    • closedAccess   Wastewater-Based Epidemiology as a Novel Biomonitoring Tool to Evaluate Human Exposure To Pollutants 

      GRACIA LOR, EMMA; Rousis, Nikolaos I; Hernandez, Felix; Zuccato, Ettore; Castiglioni, Sara ACS (2018-08-27)
      Humans are continuously exposed to pollutants by different routes, and human biomonitoring (HBM) is the tool commonly used to assess exposure to chemicals by measuring parent substances or metabolites in human specimens. ...
    • closedAccess   Wastewater-based epidemiology as a novel tool to evaluate human exposure to pesticides: Triazines and organophosphates as case studies 

      Rousis, Nikolaos I; GRACIA LOR, EMMA; Hernandez, Felix; Poretti, Francesco; Santos, Miguel M.; Zuccato, Ettore; Castiglioni, Sara Elsevier ScienceDirect (2021-06-22)
      Production and application of pesticides have risen remarkably in the last few decades. Even if they provide many benefits, they can be hazardous for humans and ecosystems when they are not used cautiously. Human exposure ...
    • closedAccess   Wastewater-based epidemiology for the assessment of population exposure to chemicals: The need for integration with human biomonitoring for global One Health actions 

      Kasprzyk-Hordern, Barbara; Been, Frederic; Bijlsma, Lubertus; Brack, Werner; Castiglioni, Sara; Covaci, Adrian; Martincigh, Bice; Mueller, Jochen; van Nuijs, Alexander; Oluseyi, Temilola; Thomas, Kevin Elsevier (2023-02-28)
      WBE has now become a complimentary tool in SARS-CoV-2 surveillance. This was preceded by the established application of WBE to assess the consumption of illicit drugs in communities. It is now timely to build on this and ...
    • closedAccess   Wastewater-based epidemiology for tracking human exposure to mycotoxins 

      GRACIA LOR, EMMA; Zuccato, Ettore; Hernandez, Felix; Castiglioni, Sara Elsevier (2019-01-27)
      Mycotoxins are among the compounds of most concern for human health because of their common presence in food and their proven toxicity for human health. Human biomonitoring (HBM) studies, foodstuff analysis and dietary ...
    • closedAccess   Wastewater-based epidemiology to assess pan-European pesticide exposure 

      Rousis, Nikolaos I; GRACIA LOR, EMMA; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Thomas, Kevin; van Nuijs, Alexander; Yang, Zhugen; Castiglioni, Sara Elsevier (2017)
      Human biomonitoring, i.e. the determination of chemicals and/or their metabolites in human specimens, is the most common and potent tool for assessing human exposure to pesticides, but it suffers from limitations such as ...