Listar PSB_Articles por autoría "2c35118d-c809-4f5d-9609-ab7254cc8f56"
Mostrando ítems 1-20 de 31
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Ambiguous-cue interpretation is biased under stress- and depression-like states in rats.
Enkel, Thomas; Gholizadeh, Donya; Von Bohlen und Halbach, Oliver; Sanchis-Segura, Carla; Hurleman, Rene; Spanagel, Rainer; Gass, Peter; Vollmayr, Barbara Nature Publishing Group (2010)Negative cognitive bias—the tendency to interpret ambiguous situations pessimistically—is a central feature of stress-related disorders such as depression. The underlying neurobiology of this bias, however, remains unclear, ... -
Are gender-science stereotypes barriers for women in science, technology, engineering, and mathematics? Exploring when, how, and to whom in an experimentally-controlled setting
Sebastián Tirado, Alba; Félix Esbrí, Sonia; Forn, Cristina; Sanchis-Segura, Carla Frontiers Media (2023)Based on Social Cognitive Career Theory principles, the present study sought to investigate whether stereotype threat experiences could act as a barrier and reduce the persistence of women in math-intensive activities. ... -
Automated scoring of fear-related behavior using EthoVision software
Pham, J.; Cabrera, S. M.; Sanchis-Segura, Carla; Wood, Mark A. Elsevier (2009)Fear conditioning is a frequently used paradigm for assessing learning and memory in rodents. Traditionally researchers have relied upon scoring of fear-related behavior by human observation, which can be difficult and ... -
Beyond “sex prediction”: estimating and interpreting multivariate sex differences and similarities in the brain
Sanchis-Segura, Carla; Aguirre, Naiara; Cruz Gómez, Álvaro Javier; Félix-Esbrí, Sonia; Forn, Cristina Elsevier ScienceDirect (2022-05-30)Previous studies have shown that machine-learning (ML) algorithms can “predict” sex based on brain anatomical/ functional features. The high classification accuracy achieved by ML algorithms is often interpreted as revealing ... -
Cerebellar hallmarks of conditioned preference for cocaine
Carbó Gas, María; Vázquez Sanromán, Dolores; Gil-Miravet, Isis; De las Heras-Chanes, Joan; Coria Ávila, Genaro A.; Manzo, Jorge; Sanchis-Segura, Carla; MIQUEL, MARTA Elsevier (2014)Pavlovian conditioning tunes the motivational drive of drug-associated stimuli, fostering the probability of those environmental stimuli to promote and trigger drug seeking and taking. Interestingly, different areas in ... -
Cerebellar perineuronal nets in cocaine-induced pavlovian memory: Site matters
Carbó Gas, María; Moreno Rius, Josep; Guarque-Chabrera, Julian; Vázquez Sanromán, Dolores; Gil-Miravet, Isis; Carulli, Daniela; Hoebeek, Freek; De Zeeuw, Chris; Sanchis-Segura, Carla; MIQUEL, MARTA Elsevier (2017-07-14)One of the key mechanisms for the stabilization of synaptic changes near the end of critical periods for experience-dependent plasticity is the formation of specific lattice extracellular matrix structures called perineuronal ... -
Cocaine-induced plasticity in the cerebellum of sensitised mice
Vázquez Sanromán, Dolores; Carbó Gas, María; Leto, Ketty; Cerezo García, Miguel; Gil-Miravet, Isis; Sanchis-Segura, Carla; Carulli, Daniela; Rossi, Ferdinando; MIQUEL, MARTA Springer Verlag (2015)Rationale Prior research has accumulated a substantial amount of evidence on the ability of cocaine to produce short- and long-lasting molecular and structural plasticity in the corticostriatal-limbic circuitry. However, ... -
Do Gender-Related Stereotypes Affect Spatial Performance? Exploring When, How and to Whom Using a Chronometric Two-Choice Mental Rotation Task
Sanchis-Segura, Carla; Aguirre, Naiara; Cruz Gómez, Álvaro Javier; Solozano Belenguer, Noemí; Forn, Cristina Frontiers Media (2018-07-24)It is a common belief that males have superior visuospatial abilities and that differences in this and other cognitive domains (e.g., math) contribute to the reduced interest and low representation of girls and women in ... -
Effects of different intracranial volume correction methods on univariate sex differences in grey matter volume and multivariate sex prediction
Sanchis-Segura, Carla; Ibáñez Gual, Maria Victoria; Aguirre, Naiara; Cruz Gómez, Álvaro Javier; Forn, Cristina Nature Research (2020)Sex differences in 116 local gray matter volumes (GMVOL) were assessed in 444 males and 444 females without correcting for total intracranial volume (TIV) or after adjusting the data with the scaling, proportions, ... -
Enhanced frontoparietal connectivity in multiple sclerosis patients and healthy controls in response to an intensive computerized training focused on working memory
Aguirre, Naiara; Cruz Gómez, Álvaro Javier; Félix Esbrí, Sonia; Miró-Padilla, Anna; Bueichekú, Elisenda; Avila, Cesar; Sanchis-Segura, Carla; Forn, Cristina; Broseta Torres, Ricardo Elsevier ScienceDirect (2021-04-24)Background: Working memory (WM) deficits are common in multiple sclerosis (MS) patients. Computerized cognitive training may enhance WM capabilities but its efficacy in MS patients has not been sufficiently explored. ... -
El entrenamiento en memoria de trabajo mejora la eficiencia cognitiva en pacientes de Esclerosis Múltiple
Aguirre, Naiara; Cruz Gómez, Álvaro Javier; Miró-Padilla, Anna; Bueichekú, Elisenda; Solozano Belenguer, Noemí; Broseta Torres, Ricardo; Avila, Cesar; Sanchis-Segura, Carla; Forn, Cristina Aten-D (2018)La Esclerosis Múltiple (EM) es una enfermedad en la que la memoria de trabajo (MT) se encuentra comúnmente afectada. Estudiar la eficacia de un programa de entrenamiento en MT en pacientes de EM. 29 pacientes de EM ... -
Epigenetic mechanisms underlying extinction of memory and drug-seeking behavior
Malvaez, Melissa; Barrett, Ruth M.; Wood, Marcelo A.; Sanchis-Segura, Carla Springer-Verlag (2009-10)An increasing body of evidence shows that structural modifications of chromatin, the DNA–protein complex that packages genomic DNA, do not only participate in maintaining cellular memory (e.g., cell fate), but they may ... -
Exploring Neural Efficiency in Multiple Sclerosis Patients during the Symbol Digit Modalities Test: A Functional Magnetic Resonance Imaging Study
Fittipaldi Márquez, María Sol; Cruz Gómez, Álvaro Javier; Sanchis-Segura, Carla; Belenguer, A.; Avila, Cesar; Forn, Cristina Karger Publishers (2017)Background: Reduced information-processing speed (IPS) is a primary cognitive deficit of multiple sclerosis (MS) patients. The neural efficiency hypothesis describes an inverse relationship between cognitive performance ... -
Gender Stereotypes Selectively Affect the Remembering of Highly Valued Professions
Sebastián Tirado, Alba; Félix Esbrí, Sonia; Forn, Cristina; Sanchis-Segura, Carla Springer (2023)This study includes two experiments designed to assess the effects of occupational gender-related stereotypes on information processing and memory performance. These two experiments were conducted in two separate cohorts ... -
Glutamate Receptors on Dopamine Neurons Control the Persistence of Cocaine Seeking
Engblom, David; Bilbao, Ainhoa; Sanchis-Segura, Carla; Dahan, Lionel; Perreau-Lenz, Stéphanie; Balland, Bénédicte; Rodríguez Parkitna, Jan; Luján, Rafael; Halbout, Briac; Mameli, Manuel; Parlato, Rosanna; Sprengel, Rolf; Lüscher, Christian; Schütz, Günther; Spanagel, Rainer Elsevier (2008-08)Cocaine strengthens excitatory synapses onto midbrain dopamine neurons through the synaptic delivery of GluR1-containing AMPA receptors. This cocaine-evoked plasticity depends on NMDA receptor activation, but its behavioral ... -
Have we been ignoring the elephant in the room? Seven arguments for considering the cerebellum as part of addiction circuitry
MIQUEL, MARTA; Vázquez Sanromán, Dolores; Carbó Gas, María; Gil-Miravet, Isis; Sanchis-Segura, Carla; Carulli, Daniela; Manzo, Jorge; Coria Ávila, Genaro A. Elsevier (2016)Addiction involves alterations in multiple brain regions that are associated with functions such as memory, motivation and executive control. Indeed, it is now well accepted that addictive drugs produce long-lasting molecular ... -
Hippocampal dysfunction is associated with memory impairment in multiple sclerosis: A volumetric and functional connectivity study
González Torre, Julio Alberto; Cruz Gómez, Álvaro Javier; Belenguer Benavides, Antonio; Sanchis-Segura, Carla; Avila, Cesar; Forn, Cristina SAGE Publications (2017)BACKGROUND: Previous studies have suggested a relationship between neuroanatomical and neurofunctional hippocampal alterations and episodic memory impairments in multiple sclerosis (MS) patients OBJECTIVE: We examined ... -
Increased regional gray matter atrophy and enhanced functional connectivy in male multiple sclerosis patients
Sanchis-Segura, Carla; Cruz Gómez, Álvaro Javier; Belenguer Benavides, Antonio; Fittipaldi Márquez, María Sol; Avila, Cesar; Forn, Cristina Elsevier (2016-09)Evidence suggests that sex/gender is an important factor for understanding multiple sclerosis (MS) and that some of its neuropathological consequences might manifest earlier in males. In the present study, we assessed gray ... -
Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine- and morphine withdrawal-related cues
Sanchis-Segura, Carla; Jancic, Dragana; Jiménez Minchán, María; Barco, Ángel Frontiers Research Foundation (2009)To investigate the role of cAMP responsive element binding protein (CREB)-dependent gene expression in morphine induced behaviors, we examined bitransgenic mice expressing a dominant and strong inhibitor of the CREB family ... -
Involving the cerebellum in cocaine-induced memory: pattern of CFOS expression in mice trained to acquire conditioned preference for cocaine
Carbó Gas, María; Vázquez Sanromán, Dolores; Aguirre Manzo, Luisa; Coria Ávila, Genaro A.; Manzo, Jorge; Sanchis-Segura, Carla; MIQUEL, MARTA Wiley (2014-01)Because of its primary role in drug-seeking, consumption and addictive behaviour, there is a growing interest in identifying the neural circuits and molecular mechanisms underlying the formation, maintenance and retrieval ...