Listar ESID_Articles por autoría "dd4c75f7-622b-4037-b654-c595260f2165"
Mostrando ítems 1-20 de 32
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A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
Cerqueira, Andreia; Romero-Gavilán, Francisco J; Araújo-Gomes, Nuno; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2020)Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ... -
A single coating with antibacterial properties for prevention of medical device-associated infections
García-Arnáez, Iñaki; Palla, B.; Suay, Julio; Romero-Gavilán, Francisco J; García Fernández, Luis Amable; Fernández Gutiérrez, Mar; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2019-04)Human bacterial pathogens found on medical implants are one of the main causes of morbidity and mortality, making the development of novel coatings the primary strategy in the prevention of medical device-associated ... -
Bioactive potential of silica coatings and its effect on the adhesion of proteins to titanium implants
Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J.J.; Carda, C.; Gurruchaga, Marilo; Suay, Julio; Goñi, Isabel Elsevier (2018-02-01)There is an ever-increasing need to develop dental implants with ideal characteristics to achieve specific and desired biological response in the scope of improve the healing process post-implantation. Following that ... -
Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Iloro, Ibon; Azkargorta, Mikel; Elortza, Felix; Izquierdo Escrig, Raul; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2020-12-30)Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ... -
Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Izquierdo Escrig, Raul; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Suay, Julio; Goñi, Isabel Elsevier (2021-06-01)Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ... -
Characterization of serum proteins attached to distinct sol–gel hybrid surfaces
Gomes, Nuno; Romero-Gavilán, Francisco J; Sánchez-Pérez, Ana María; GURRUCHAGA, MARILO; Azkargorta, Mikel; Elortza, Felix; Ibáñez, Maria; Iloro, Ibon; Suay, Julio; Goñi, Isabel Wiley (2017-07)The success of a dental implant depends on its osseointegration, an important feature of the implant biocompatibility. In this study, two distinct sol–gel hybrid coating formulations [50% methyltrimethoxysilane: 50% ... -
Comparison of patient-centered outcomes measures between low-speed drilling without irrigation and high-speed drilling with irrigation: A randomized clinical trial
Bernabeu Mira, Juan Carlos; Penarrocha-Diago, Miguel; Penarrocha-Diago, Maria; Romero-Gavilán, Francisco J; Camacho-Alonso, Fabio; Penarrocha-Oltra, David Wiley (2023-10-06)Objective To compare patient satisfaction during surgery, postoperative pain and inflammation and quality of life between high-speed drilling with irrigation and low-speed drilling without irrigation for implant bed ... -
Complement proteins regulating macrophage polarisation on biomaterials
Gomes, Nuno; Romero-Gavilán, Francisco J; Zhang, Yiyue; Martinez Ramos, Cristina; Elortza, Felix; Azkargorta, Mikel; Martín de Llano, J. J.; GURRUCHAGA, MARILO; Goñi, Isabel; van den Beucken, J.J.J.P.; Suay, Julio Elsevier (2019-09-01)One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ... -
Complex effects of Mg-biomaterials on the osteoblast cell machinery: A proteomic study
Cerqueira, Andreia; García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Azkargorta, Mikel; Elortza, Felix; Martín de Llanos, José Javier; Carda, Carmen; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2022)The cell–biomaterial interface is highly complex; thousands of molecules and many processes participate in its formation. Growing demand for improved biomaterials has highlighted the need to understand the structure and ... -
Control of the degradation of silica sol-gel hybrid coatings for metal implants prepared by the triple combination of alkoxysilanes
Romero-Gavilán, Francisco J; Barros Silva, S.; García-Cañadas, Jorge; Palla, B.; Izquierdo Escrig, Raul; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Elsevier (2016)Hybrid materials obtained by sol-gel process are able to degrade and release Si compounds that are useful in regenerative medicine due to their osteoinductive properties. The present work studies the behavior of new ... -
Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis
García-Arnáez, Iñaki; Romero-Gavilán, Francisco J; Cerqueira, Andreia; Elortza, Felix; Azkargorta, Mikel; Muñoz Guzón, Fernando; Mata Roig, Manuel; MARTIN DE LLANO, JOSE JAVIER; Suay, Julio; GURRUCHAGA, MARILO; Goñi, Isabel Elsevier (2022-10-21)Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ... -
Design of nanostructured siloxane-gelatin coatings: Immobilization strategies and dissolution properties
Ibáñez, Maria; Aldalur, I.; Romero-Gavilán, Francisco J; Suay, Julio; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2018-02)Owing to the outstanding service life of metallic prostheses, a substantial effort has been put into their surface modification to improve biocompatibility and reduce metallic ion diffusion. To satisfy these requirements, ... -
Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes
García-Arnáez, Iñaki; Cerqueira, Andreia; Romero-Gavilán, Francisco J; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; Suay, Julio; Goñi, Isabel; GURRUCHAGA, MARILO Elsevier (2022)Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of osteoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ... -
Enhancing the correlation between in vitro and in vivo experiments in dental implant osseointegration: investigating the role of Ca ions
Romero-Gavilán, Francisco J; Cerqueira, Andreia; Anitua, Eduardo; Muñoz, Fernando; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Tejero, Ricardo Royal Society of Chemistry (2024-02-16)This study delves into the osteogenic potential of a calcium-ion modified titanium implant surface, unicCa, employing state-of-the-art proteomics techniques both in vitro (utilizing osteoblasts and macrophage cell cultures) ... -
Evaluation of the inflammatory responses to sol–gel coatingswith distinct biocompatibility levels
Cerqueira, Andreia; Araújo-Gomes, Nuno; Zhang, Yang; van den Beucken, Jeroen; Martínez Ramos, Cristina; ozturan, seda; Izquierdo Escrig, Raul; Muriach, Maria; Romero Cano, Ricard; Baliño, Pablo; Romero-Gavilán, Francisco J John Wiley and Sons (2021-02-20)The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further, cellular oxidative stress resulting from the material recognition ... -
Influence of abutment shape on peri-implant tissue conditions: A randomized clinical trial
Bernabeu Mira, Juan Carlos; Peñarrocha-Diago, Maria; Viña-Almunia, Jose; Romero-Gavilán, Francisco J; Pérez-Sayans, Mario; Peñarrocha-Oltra, David John Wiley & Sons Ltd. (2023-07-17)Objective: To analyze the influence of 3-mm high abutments with different shapes (cylindrical abutment vs. wide abutment) on marginal bone-level changes (bone loss and bone remodeling). The influence of abutment shape ... -
Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration
Anitua, Eduardo; Cerqueira, Andreia; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Ozturan, Seda; Azkagorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio; Tejero, Ricardo Springer (2021-04-21)Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ions (Ca-ion) ... -
Insight into the antibacterial mechanism of Cu-enriched sol–gel coatings employing proteomics
Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Cerqueira, Andreia; Scalschi, Loredana; Vicedo, Begonya; Villagrasa, Alejandro; Izquierdo, Raúl; Elortza, Felix; Gurruchaga, Mariló; Goñi, Isabel; Suay, Julio Royal Society of Chemistry (2023)Advanced antibacterial biomaterials can help reduce the severe consequences of infections. Using copper compounds is an excellent option to achieve this goal; they offer a combination of regenerative and antimicrobial ... -
Osseointegration mechanisms: a proteomic approach
Gomes, Nuno; Romero-Gavilán, Francisco J; García-Arnáez, Iñaki; Martinez Ramos, Cristina; Sánchez-Pérez, Ana María; Azkargorta, Mikel; Elortza, Felix; Martín de Llano, J.J.; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Springer-Verlag (2018-03)The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration and to short the time needed to achieve it. Design of implants nowadays involves changes in ... -
Osteointegración de implantes de titanio con superficies activas. Un estudio proteómico
Romero-Gavilán, Francisco J; Gomes, Nuno; Sánchez-Pérez, Ana María; García-Arnáez, Iñaki; Azkargorta, Mikel; Elortza, Felix; GURRUCHAGA, MARILO; Goñi, Isabel; Suay, Julio Ediciones Peldaño (2017-12)Titanium is a biomaterial largely used on dental implant manufacturing. However, as a consequence of its intrinsically low bioactivity, the development of distinct superficial treatments in order to enhance its ...