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Electrical pumping of potassium ions against an external concentration gradient in a biological ion channel
dc.contributor.author | Aguilella, Vicente | |
dc.contributor.author | Alcaraz, Antonio | |
dc.contributor.author | Ramírez, Patricio | |
dc.contributor.author | García Giménez, Elena | |
dc.contributor.author | Mafe, Salvador | |
dc.contributor.author | Queralt-Martín, María | |
dc.date.accessioned | 2014-03-10T08:35:15Z | |
dc.date.available | 2014-03-10T08:35:15Z | |
dc.date.issued | 2013-07-22 | |
dc.identifier.citation | Applied Physics Letters, v. 103, issue 4 (2013, Jul 22), p. 043707-1 -- 043707-4 | ca_CA |
dc.identifier.uri | http://hdl.handle.net/10234/86131 | |
dc.description.abstract | We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel rectifying properties can be used to pump potassium ions against an external concentration gradient under asymmetric pH conditions. The results are discussed in terms of the ionic selectivity and rectification ratio of the channel. The physical concepts involved may be applied to separation processes with synthetic nanopores and to bioelectrical phenomena | ca_CA |
dc.format.extent | 4 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | AIP Publishing | ca_CA |
dc.rights | Attribution-NonCommercial-ShareAlike 4.0 Spain | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | * |
dc.subject | Bioelelectric phenomena | ca_CA |
dc.subject | Biomembrane transport | ca_CA |
dc.subject | microorganisms | ca_CA |
dc.subject | pH | ca_CA |
dc.subject | Positive ions | ca_CA |
dc.subject | Potassium | ca_CA |
dc.subject | Separation | ca_CA |
dc.subject | Ion channels | ca_CA |
dc.subject | Fenómenos bioeléctricos | ca_CA |
dc.subject | Transporte de biomembranas | ca_CA |
dc.subject | Microorganismos | ca_CA |
dc.subject | Iones positivos | ca_CA |
dc.subject | Potasio | ca_CA |
dc.subject | Separación | ca_CA |
dc.subject | Canales iónicos | ca_CA |
dc.title | Electrical pumping of potassium ions against an external concentration gradient in a biological ion channel | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | http://dx.doi.org/10.1063/1.4816748 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca_CA |
dc.relation.publisherVersion | http://scitation.aip.org/content/aip/journal/apl/103/4/10.1063/1.4816748 | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion |
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