Electrical pumping of potassium ions against an external concentration gradient in a biological ion channel
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Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/2507
comunitat-uji-handle3:10234/6973
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Título
Electrical pumping of potassium ions against an external concentration gradient in a biological ion channelAutoría
Fecha de publicación
2013-07-22Editor
AIP PublishingCita bibliográfica
Applied Physics Letters, v. 103, issue 4 (2013, Jul 22), p. 043707-1 -- 043707-4Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://scitation.aip.org/content/aip/journal/apl/103/4/10.1063/1.4816748Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel ... [+]
We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel rectifying properties can be used to pump potassium ions against an external concentration gradient under asymmetric pH conditions. The results are discussed in terms of the ionic selectivity and rectification ratio of the channel. The physical concepts involved may be applied to separation processes with synthetic nanopores and to bioelectrical phenomena [-]
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info:eu-repo/semantics/openAccess
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