Electrical pumping of potassium ions against an external concentration gradient in a biological ion channel
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Electrical pumping of potassium ions against an external concentration gradient in a biological ion channelAutoria
Data de publicació
2013-07-22Editor
AIP PublishingCita bibliogràfica
Applied Physics Letters, v. 103, issue 4 (2013, Jul 22), p. 043707-1 -- 043707-4Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
http://scitation.aip.org/content/aip/journal/apl/103/4/10.1063/1.4816748Versió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel ... [+]
We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel rectifying properties can be used to pump potassium ions against an external concentration gradient under asymmetric pH conditions. The results are discussed in terms of the ionic selectivity and rectification ratio of the channel. The physical concepts involved may be applied to separation processes with synthetic nanopores and to bioelectrical phenomena [-]
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info:eu-repo/semantics/openAccess
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