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Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction : the modifying role of obesity
(Elsevier ScienceDirect, 2024-06-12)
This study investigates the association between maximal functional capacity (peakVO2) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in 133 ambulatory patients with heart failure with preserved ejection fraction ...
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
(2024)
Background: International guidelines recommend targeted screening to identify gestational thyroid dysfunction. However, currently used risk factors have questionable discriminative ability. We quantified the risk for thyroid ...
Comparison of baseline clinical characteristics among people with type 2 diabetes on second-line therapy previously added with dapagliflozin or another oral glucose-lowering drug: AGORA study
(Elsevier, 2024)
Introduction: Type 2 diabetes mellitus (T2D) has acquired epidemic proportions worldwide.
In recent years, new oral glucose-lowering drugs (OGLD) have emerged that improve the
cardiovascular---kidney---metabolic control ...
Glioblastoma Therapy: Past, Present and Future
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-03-01)
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer. Although great efforts have been made by clinicians and researchers, no significant improvement in survival has been achieved since the ...
Folic Acid Supplementation during Pregnancy and Its Association with Telomere Length in Children at Four Years: Results from the INMA Birth Cohort Study
(MDPI, 2023)
This study examined the association between folic acid supplements (FAs) during different
periods of pregnancy and offspring telomere length (TL) at age four in 666 children from the INMA
study. FAs were self-reported ...
Development and Psychometric Properties of the Spanish Social Stigma Scale (S3)
(2024)
Background: Mental health problems are associated with negative connotations that
may lead to discrimination and rejection of people diagnosed with mental disorders. The present
study aimed to develop and validate a new ...
Unraveling the Mechanisms Behind Exercise Intolerance and Recovery in Long COVID
(Elsevier, 2024)
Background: Patients suffering from long COVID may exhibit autonomic dysregulation. However, the association between autonomic dysregulation and exercise intolerance and the impact of therapeutic interventions on its ...
Hippocampal dopamine receptors modulate cFos expression in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus
(Elsevier, 2005-12)
Recently, we have shown that D1 and D2 receptors in the ventral hippocampus (VH) modulate both the locomotor activation and the increase in dopamine (DA) levels in the rat nucleus accumbens (NAc) induced by NMDA stimulation ...
Inhibition of the medial amygdala disrupts escalated aggression in lactating female mice after repeated exposure to male intruders
(Nature Research, 2022-09-16)
Virgin female laboratory mice readily express pup care when co-housed with dams and pups. However, pup-sensitized virgins fail to express intruder-directed aggression on a single session of testing. To study whether repeated ...
Novel sampling strategy for alive animal volatolome extraction combined with GC-MS based untargeted metabolomics: Identifying mouse pup pheromones
(Elsevier, 2021-08-04)
In this study, we identify 11 mouse pup volatiles putatively involved in maternal care induction in adult females. For this purpose, we have adapted the dynamic headspace methodology to extract the volatolome of whole alive ...