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Association between several immune response-related genes and the effectiveness of biological treatments in patients with moderate-to-severe psoriasis
(Wiley, 2024-01-04)
Biological therapies are safer and more effective against psoriasis than conventional treatments. Even so, 30–50% of psoriatic patients show an inadequate response, which is associated with individual genetic heterogeneity. ...
Role of Exosomal miR-205-5p Cargo in Angiogenesis and Cell Migration
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-01-11)
Exosomes or small extracellular vesicles (sEVs) represent a pivotal component in intercellular communication, carrying a diverse array of biomolecules. Several factors can affect sEVs release dynamics, as occurs in ...
Small Extracellular Vesicles and Oxidative Pathophysiological Mechanisms in Retinal Degenerative Diseases
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-01-28)
This review focuses on the role of small extracellular vesicles in the pathophysiological mechanisms of retinal degenerative diseases. Many of these mechanisms are related to or modulated by the oxidative burden of retinal ...
Emerging Hyalomma lusitanicum: From identification to vectorial role and integrated control
(Wiley, 2023)
In the Mediterranean basin, the tick species Hyalomma lusitanicum Koch stands out among
other species of the Hyalomma genus due to its wide distribution, and there is great concern about its potential role as a vector ...
Physicians’ perception of oral nutritional supplement acceptance and tolerability in malnourished outpatients: PerceptiONS study
(MDPI, 2023-02-28)
Malnutrition is a common condition associated with various pathologies such as infections, neoplasms and digestive system disorders. Patients can be managed using different strategies, which include dietary modifications ...
Mediators of the association between maternal body mass index and breastfeeding duration in 3 international cohorts
(Elsevier, 2023-07)
Background:
Maternal obesity has been associated with shorter breastfeeding duration, but little is known about mediating factors explaining this association. It is important to assess these relationships across diverse ...
Experience sampling methods for the personalised prediction of mental health problems in Spanish university students: protocol for a survey-based observational study within the PROMES-U project
(BMJ Publishing Group, 2023-07)
Introduction: There is a high prevalence of mental health problems among university students. Better prediction and treatment access for this population is needed. In recent years, short-term dynamic factors, which can be ...
Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells
(Frontiers Media, 2022)
Patients with glioblastoma (GBM) face a dismal prognosis. GBMs are driven by glioblastoma stem cells (GSCs) that display a neural stem cell (NSC)-like phenotype. These glioblastoma stem cells are often in a quiescent state ...
Multidisciplinary management of cardiovascular disease in women: Delphi consensus
(Frontiers, 2024)
Background: Current clinical guidelines on cardiovascular disease (CVD) do not
specifically address the female population. The aim of this consensus is to know
the opinion of a group of experts on the management of CVD ...
Prediction of Alzheimer’s Disease by a Novel Image-Based Representation of Gene Expression
(MDPI, 2022)
Early intervention can delay the progress of Alzheimer’s Disease (AD), but currently, there are no effective prediction tools. The goal of this study is to generate a reliable artificial intelligence (AI) model capable of ...