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Prenatal exposure to mercury and longitudinally assesssed fetal growth: Relation and effect modifiers
(Elsevier, 2018-01)
Background:Prenatal mercury exposure has been related to reductions in anthropometry at birth. Levels ofmercury have been reported as being relatively elevated in the Spanish population.Objective:To investigate the relation ...
Immunogold Labeling to Detect Streptococcus pyogenes Cas9 in Cell Culture and Tissues by Electron Microscopy
(Mary Ann Liebert, 2019)
The CRISPR-Cas9 system is a powerful and yet precise DNA-editing tool in rapid development. By combining immunogold labeling and electron microscopy with the novel CRISPR-Cas9 system, we propose a new method to gain insight ...
Fisiopatología renal y mecanismos farmacológicos de nefroprotección
(Elsevier, 2023-06)
Son varios los factores de riesgo que pueden afectar la progresión de la enfermedad
renal crónica (ERC). La hipertensión arterial, la proteinuria, la obesidad, la hipertensión
intraglomerular, el tabaco y el control ...
Maternal Smoking During Pregnancy and Fetal Biometry: The INMA Mother and Child Cohort Study
(Oxford University Press, 2013-10-01)
In utero tobacco exposure has been associated with fetal growth restriction, but uncertainty remains about critical windows of exposure and specific effects on body segments. In the present study, we aimed to examine the ...
Evidence of oligodendrogliosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism
(Wiley, 2013)
Aims: Mice and nonhuman primates administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) represent elective experimental models of Parkinsonism, in which degeneration of the nigrostriatal dopaminergic pathway ...
Metalloproteinase-9 contributes to inflammatory glia activation and nigro-striatal pathway degeneration in both mouse and monkey models of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism
(Springer, 2014-02)
Inflammation is a predominant aspect of neurodegenerative diseases, manifested by glia activation and expression of pro-inflammatory mediators. Studies on animal models of Parkinson’s disease (PD) suggest that sustained ...
Functional role of Barrington’s nucleus in the micturition reflex: Relevance in the surgical treatment of Parkinson’s disease
(Elsevier, 2014)
The pontine micturition center or Barrington’s nucleus (BN) – besides regulating micturition – co-regulates the activity of other pelvic viscera such as the colon and genitals. At present, this issue is gaining particular ...
Prenatal and postnatal insecticide use and infant neuropsychological development in a multicenter birth cohort study
(Elsevier, 2013)
There is little evidence about exposure to currently used insecticides during early life periods and adverse effects on child neuropsychological development. The aim of this study is to examine the association between ...
The use of lower or higher than recommended doses of folic acid supplements during pregnancy is associated with child attentional dysfunction at 4-5 years of age in the INMA Project
(MDPI, 2021-01-23)
We assessed the association between the use of lower- and higher-than-recommended doses of folic acid supplements (FAs) during pregnancy and attentional function in boys and girls at age of 4-5. We analyzed data from 1329 ...
Exposure to per- and polyfluoroalkyl substances and premature skin aging
(Elsevier, 2020-10-24)
Per- and polyfluoroalkyl substances (PFASs) are a ubiquitous group of persistent chemicals distributed globally in the environment. Skin aging is a notorious process that is prematurely induced by the interaction between ...