Listar MED_Articles por título
-
The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction
Oxford University Press (2016-01-07)Background NRTIs are essential components of HIV therapy with well-documented, long-term mitochondrial toxicity in hepatic cells, but whose acute effects on mitochondria are unclear. As acetaminophen-induced hepatotoxicity ... -
The role of mucin 1 in respiratory diseases
European Respiratory Society (2021-03-31)Recent evidence has demonstrated that mucin 1 (MUC1) is involved in many pathological processes that occur in the lung. MUC1 is a transmembrane protein mainly expressed by epithelial and hematopoietic cells. It has a ... -
The role of parental social class, education and unemployment on child cognitive development
Sociedad Española de Salud Pública y Administración Sanitaria (2020-01)Objective: Assessing the association between socioeconomic gradient and cognitive development among children of a Spanish birth cohort aged 5-6 years from a gender perspective. Method: Cognitive development was assessed ... -
The role of the cerebellum in drug-cue associative memory: functional interactions with the medial prefrontal cortex
John Wiley (2018-10-02)Drug-induced Pavlovian memories are thought to be crucial for drug addiction because they guide behaviour towards environments with drug availability. Drug-related memory depends on persistent changes in dopamine-glutamate ... -
The rostromedial tegmental nucleus RMTg is not a critical site for ethanol-induced motor activation in rats
Springer Nature (2023-07-20)-Rationale : Opioid drugs indirectly activate dopamine (DA) neurons in the ventral tegmental area (VTA) through a disinhibition mechanism mediated by mu opioid receptors (MORs) present both on the GABA projection neurons ... -
The TrkB agonist 7,8-dihydroxyflavone changes the structural dynamics of neocortical pyramidal neurons and improves object recognition in mice
Springer Verlag (2018-06)BDNF and its receptor TrkB have important roles in neurodevelopment, neural plasticity, learning, and memory. Alterations in TrkB expression have been described in different CNS disorders. Therefore, drugs interacting with ... -
The Use of Barbed Suture for Vaginal Cuff Closure in Total Laparoscopic Hysterectomy
MedCrave (2015-12)Objective: The aim of this work is to evaluate the safety and efficacy of the barbed unidirectional suture in a total laparoscopic hysterectomy. Materials and Methods: A retrospective and descriptive study was conducted, ... -
The use of lower or higher than recommended doses of folic acid supplements during pregnancy is associated with child attentional dysfunction at 4-5 years of age in the INMA Project
MDPI (2021-01-23)We assessed the association between the use of lower- and higher-than-recommended doses of folic acid supplements (FAs) during pregnancy and attentional function in boys and girls at age of 4-5. We analyzed data from 1329 ... -
Thyrotoxicosis following SARS-COV-2 vaccination: a case series and discussion
Springer (2022-01-11)Aim To describe a case series of thyrotoxicosis likely triggered by SARS-CoV-2 vaccination and to warn physicians about this potential correlation. To report clinical, laboratory and imaging fndings and provide further ... -
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Nature Research (2020)n rodent models of type 2 diabetes (T2D), sustained remission of hyperglycemia can be induced by a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1), and the mediobasal hypothalamus (MBH) ... -
Trastorno por déficit de atención con hiperactividad y trastorno bipolar en gemelas dicigóticas. A propósito de un caso
Elsevier España (2008-03)Desde que Wozniak et al describieran una elevada incidencia de trastorno bipolar (16%) entre los niños y adolescentes diagnosticados de trastorno por déficit de atención con hiperactividad (TDAH) ha existido un interés ... -
Trastornos de personalidad, Trastornos por uso de sustancias y transeuntismo
Sociedad Española de Patología Dual (2015)The prevalence of mental disorders is higher in drug users and in the homeless population than in the population not affected by these conditions, although there are no studies that specifically compare the clinical and ... -
Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature
Dove Medical Press (2014)Background: Treatment adherence is one of the key factors for achieving optimal clinical outcomes. In order to assess costs related to adherence to, and persistence and compliance with, disease-modifying therapies (DMTs) ... -
Treatment and Follow-up in an Asymptomatic Malignant Struma Ovarri: A case report
Elsevier (2017)Introduction Struma ovarii is a rare ovarian tumor, representing 0.5-1% of all ovarian tumors and 2–5% of ovarian teratomas. It is defined as an ovarian teratoma composed mostly of thyroid tissue. The symptoms are ... -
Treatment decision-making in chronic lymphocytic leukaemia: Key factors for healthcare professionals. PRELIC study
Elsevier (2019-04-03)Objective: To explore the preferences of Spanish healthcare professionals (haematologists and hospital pharmacists) for the treatment selection of active Chronic Lymphocytic Leukaemia (CLL) patients at first relapse, condition ... -
Treatment patterns and use of healthcare resources of patients with atherosclerotic cardiovascular disease and hypercholesterolemia and patients with familial hypercholesterolemia in Spain: Protocol of the Reality study
Frontiers Media (2022)Background: Atherosclerotic cardiovascular diseases (ASCVD) and dyslipidemia are associated to a higher risk of cardiovascular events, mortality, use of healthcare resources and costs. In Spain, the evidence about the ... -
Tumor del estroma gastrointestinal rectal: diagnóstico con biopsia guiada por ecografía endovaginal
Sociedad Mexicana de Radiología e Imagen, A. C. (2015-01)Presentamos el que creemos es el segundo caso de tumor del estroma rectal, diagnosticado por biopsia con aguja gruesa guiada por ecografía endovaginal, después del primer caso presentado por Takano y sus colaboradores. ... -
Tuning the brain for motherhood: prolactin-like central signalling in virgin, pregnant, and lactating female mice
Springer (2016-06)Prolactin is fundamental for the expression of maternal behaviour. In virgin female rats, prolactin administered upon steroid hormone priming accelerates the onset of maternal care. By contrast, the role of prolactin in ... -
Two Clinical Cases of Li-Fraumeni Syndrome and Prostate Cancer: Genetic Counseling and Clinical-Surgical Management.
Elsevier (2022-06-09)The present article treats about Li-Fraumeni syndrome (LFS), a genetic disease with autosomal dominant transmission which is associated with an increased predisposition to suffer certain cancers. However, prostate cancer ...