Listar MED_Articles por autoría "ff23361f-e8b4-4a49-b3f7-aa652be176fd"
Mostrando ítems 21-39 de 39
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Los desafíos del profesorado clínico en la educación médica
Palau, Patricia; Domínguez Mafé, Eloy; Llueca, Antoni; Nuñez, Julio; Bertomeu-González, Vicente; Sanchez-Andres, Juan V.; Pallarés-Carratalá, Vicente Elsevier (2017-11-04)Background: There is a unique particularity of clinical teaching in medical education that isbeyond knowledge, skills or teaching methods of each clinician: this is clinical teaching context.This study aimed to analyze the ... -
Matrix metalloproteinase-12 cleaved fragment of titin as a predictor offunctional capacity in patients with heart failure and preserved ejection fraction
Palau, Patricia; Reese-Petersen, Alexander; Domínguez Mafé, Eloy; Ramón, José María; López, Laura; Mollar, Anna; Chorro, Francisco J.; Sanchis, Juan; Núñez, Julio Taylor and Francis (2020)Objectives.Serum levels of matrix metalloproteinase-12 cleaved fragment of titin (TIM), a novel circula-tory biomarker specific for cardiac titin degradation, has emerged as a potential biomarker in cardio-vascular diseases. ... -
Maximal functional capacity in subjects with isolated left bundle branch block: A pilot study
Palau, Patricia; Mendez, Jose; Santas, Enrique; Núñez, Julio; López López, Laura; Briatore, Antonio Ernesto; Domínguez Mafé, Eloy Wiley (2023-02-08)Background Left bundle branch block (LBBB) has been commonly associated with adverse cardiovascular (CV) events, but the effect of an isolated LBBB on maximal functional capacity is not well characterized. Objective To ... -
Noninvasive Imaging Estimation of Myocardial Iron Repletion Following Administration of Intravenous Iron: The Myocardial-IRON Trial
Núñez, Julio; Miñana, Gema; Cardells, Ingrid; Palau, Patricia; Llàcer, Pau; Facila Rubio, Lorenzo; Almenar-Bonet, Luis; Lopez-Lereu, Maria Pilar; Monmeneu Menadas, Jose Vicente; Amiguet Comins, Martina; González, Jessika; Serrano, Alicia; Montagud, Vicente; López‐Vilella, Raquel; Valero, Ernesto; García-Blas, Sergio; Bodí, Vicent; De la Espriella, Rafael; Lupón, Josep; Navarro, Jorge; Górriz, José Luis; Sanchis, Juan American Heart Association (2020-02-13)Background Intravenous ferric carboxymaltose (FCM) improves symptoms, functional capacity, and quality of life in heart failure and iron deficiency. The mechanisms underlying these effects are not fully understood. The ... -
Plasma neutrophil gelatinase-associated lipocalin and long-term mortality in patients with acute heart failure and normal renal function
Miñana, Gema; Rumiz, Eva; Palau, Patricia; Valero, Ernesto; Bodí, Vicent; Núñez, Eduardo; Sanchis, Juan; Núñez, Julio Elsevier (2016)Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a renal tubular marker for early renal dysfunction [1]. Recent studies highlighted its role in predicting acute kidney injury (AKI) and clinical outcomes in ... -
Procalcitonin and long-term prognosis after an admission for acute heart failure
Villanueva, María Pilar; Mollar, Anna; Palau, Patricia; Carratalá, Arturo; Núñez, Eduardo; Santas, Enrique; Bodí, Vicent; Chorro, Francisco J.; Miñana, Gema; Blasco, María L.; Sanchis, Juan; Núñez, Julio Elsevier (2015)Background Traditionally, procalcitonin (PCT) is considered a diagnostic marker of bacterial infections. However, slightly elevated levels of PCT have also been found in patients with heart failure. In this context, it ... -
Prognostic value of the interaction between galectin-3 and antigen carbohydrate 125 in acute heart failure
Núñez, Julio; Rabinovich, Gabriel A.; Sandino, Justo; Mainar, Luis; Palau, Patricia; Santas, Enrique; Villanueva, María Pilar; Núñez, Eduardo; Bodí, Vicent; Chorro, Francisco J.; Miñana, Gema; Sanchis, Juan Public Library of Science (2015)Aims Galectin-3 (Gal-3) and carbohydrate antigen 125 (CA125) have emerged as robust prognostic biomarkers in heart failure. Experimental data have also suggested a potential molecular interaction between CA125 and Gal-3; ... -
Rehospitalization burden and morbidity risk in patients with heart failure with mid-range ejection fraction
Santas, Enrique; De la Espriella, Rafael; Palau, Patricia; Miñana, Gema; Amiguet Comins, Martina; Sanchis, Juan; Lupón, Josep; Bayes-Genis, Antoni; Chorro, Francisco J.; Núñez, Julio Wiley (2020-03-25)Aims Heart failure with mid-range ejection fraction (HFmrEF) has been proposed as a distinct HF phenotype, but whether patients on this category fare worse, similarly, or better than those with HF with reduced EF (HFrEF) ... -
Right Ventricular Dysfunction Staging System for Mortality Risk Stratifiction in Heart Failure with Preserved Ejection Fraction
Santas, Enrique; De la Espriella, Rafael; Chorro, Francisco J.; Palau, Patricia; Miñana, Gema; Heredia, Raquel; Amiguet Comins, Martina; Merenciano Gonzalez, Hector; Sanchis, Juan; Lupón, Josep; Bayes-Genis, Antoni; Núñez, Julio MDPI (2020-03-18)Right ventricular dysfunction (RVD) parameters are increasingly important features in heart failure with preserved ejection fraction (HFpEF). We sought to evaluate the prognostic impact of a progressive RVD staging system ... -
Sacubitril/valsartan and short-term changes in the 6-minute walk test: A pilot study
Beltrán, Paola; Palau, Patricia; Domínguez Mafé, Eloy; Faraudo, Mercedes; Núñez, Eduardo Elsevier (2018-02)Background Impaired exercise capacity is the most disabling symptom in patients with heart failure with reduced ejection fraction (HFrEF). Despite sacubitril/valsartan showing reduced long-term morbidity and mortality ... -
Sex differences on peak oxygen uptake in heart failure
Palau, Patricia; Domínguez Mafé, Eloy; Núñez, Julio Wiley (2019-10)Women represent nearly half of the adult heart failure (HF) population and they remain underrepresented in HF studies. We aimed to evaluate the evidence about peak oxygen uptake (peak VO2) for clinical stratification in ... -
Sex-differential effect of frailty on long-termmortality in elderly patients after an acute coronary syndrome
Núñez, Julio; Palau, Patricia; Sastre, Clara; D'Ascoli, Giulio; Ruiz, Vicente; Bonanad, Clara; Miñana, Gema; Núñez, Eduardo; Sanchis, Juan Elsevier (2019-12-31)Background The potential sex-differential effect of frailty in patients with acute coronary syndromes (ACS) has not been well-evaluated. We sought to examine the sex-differential association between frailty status on ... -
Short-term Changes in Hemoglobin and Changes in Functional Status, Quality of Life and Natriuretic Peptides After Initiation of Dapagliflozin in Heart Failure With Reduced Ejection Fraction
Lorenzo, Miguel; Miñana, Gema; Palau, Patricia; Amiguet, Martina; Seller, Julia; García Pinilla, José Manuel; Villar, Sandra; De la Espriella, Rafael; Núñez, Eduardo; Górriz, José Luis; Valle, Alfonso; Bodí, Vicent; Sanchis, Juan; Bayes-Genis, Antoni; Núñez, Julio; DAPA-VO2 Investigators Elsevier (2023-05)Background: We aimed to evaluate the effect of dapagliflozin on short-term changes in hemoglobin in patients with stable heart failure with reduced ejection fraction (HFrEF) and whether these changes mediated the effect ... -
Short-term effects of dapagliflozin on maximal functional capacity in heart failure with reduced ejection fraction (DAPA-VO2): a randomized clinical trial
Palau, Patricia; Amiguet Comins, Martina; Domínguez Mafé, Eloy; Sastre, Clara; Mollar, Anna; Seller, Julia; GARCIA-PINILLA, JOSE MANUEL; Larumbe, Ainoha; Valle, Alfonso; Gómez Doblas, Juan José; De la Espriella, Rafael; Miñana, Gema; Robles Mezcua, Ainhoa; Santas, Enrique; Bodí, Vicent; Sanchis, Juan; Pascual-Figal, Domingo A.; Gorriz, Jose Luis; Bayes-Genis, Antoni; Núñez, Julio Wiley (2022-05-23)Aims This study aimed to evaluate the effect of dapagliflozin on 1 and 3-month maximal functional capacity in patients with stable heart failure with reduced ejection fraction (HFrEF). Methods and results In this ... -
Short-term high altitude exposure at 3454 m is well tolerated in patients with stable heart failure
Schmid, Jean-Paul; Nobel, Daniel; Brugger, Nicolas; Palau, Patricia; Trepp, Anja; Wilhelm, Matthias; Saner, Hugo Wiley (2015)Aims High altitude exposure for the purpose of tourism is very popular in mountainous regions and is considered to be safe for patients with stable CAD and preserved LV function. The purpose of this study was to evaluate ... -
Six-minute walk test in moderate to severe heart failure with preserved ejection fraction: Useful for functional capacity assessment?
Palau, Patricia; Domínguez Mafé, Eloy; Núñez, Eduardo; Sanchis, Juan; Santas, Enrique; Núñez, Julio Elsevier (2016-01-15)Despite improvements in medical treatment and prevention, heart failure (HF) remains a major cause of morbidity and mortality worldwide [1]. Currently, HF with preserved ejection fraction (HFpEF) has become the most prevalent ... -
Unraveling the Mechanisms Behind Exercise Intolerance and Recovery in Long COVID
Palau, Patricia; Calvo, Beatriz; Sastre, Clara; Domínguez Mafé, Eloy; Marín, Paloma; Flor, Cristina; Núñez, Julio; López, Laura Elsevier (2024)Background: Patients suffering from long COVID may exhibit autonomic dysregulation. However, the association between autonomic dysregulation and exercise intolerance and the impact of therapeutic interventions on its ... -
Usefulness of Right Ventricular to Pulmonary Circulation Coupling as an Indicator of Risk for Recurrent Admissions in Heart Failure With Preserved Ejection Fraction
Santas, Enrique; Palau, Patricia; Guazzi, Marco; De la Espriella, Rafael; Miñana, Gema; Sanchis, Juan; Bayes-Genis, Antoni; Lupón, Josep; Chorro, Francisco J.; Núñez, Julio Elsevier (2019)In recent years, the study of right ventricular (RV) to pulmonary circulation (PC) coupling in heart failure with preserved ejection fraction (HFpEF) has been a matter of special interest. Tricuspid annular plane systolic ... -
β-Blocker Withdrawal and Functional Capacity Improvement in Patients With Heart Failure With Preserved Ejection Fraction
Palau, Patricia; De la Espriella, Rafael; Seller, Julia; Santas, Enrique; Domínguez Mafé, Eloy; VV.AA. American Medical Association (2024-02-07)Importance: Increasing the patient's heart rate (HR) has emerged as a therapeutic option in patients with heart failure with preserved ejection fraction (HFpEF). However, the evidence is conflicting, and the profile of ...