Listar MED_Articles por autoría "cfff684d-b7eb-48d6-9b58-23a6dc8c6e30"

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    • openAccess   Perineuronal Net Formation and the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus 

      Mirzadeh, Zaman; Alonge, Kimberly; Cabrales, Elaine; Herranz-Pérez, Vicente; Scarlett, Jarrad M.; Brown, Jenny M.; Hassouna, Rim; Matsen, Miles E.; Nguyen, Hong T.; García-Verdugo, Jose Manuel; Zeltser, Lori; Schwartz, Michael Nature Research (2019)
      In leptin-deficient ob/ob mice, obesity and diabetes are associated with abnormal development of neurocircuits in the hypothalamic arcuate nucleus (ARC)1, a critical brain area for energy and glucose homoeostasis2,3. Because ...

    • openAccess   Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission 

      Bentsen, Marie A.; Rausch, Dylan Matthew; Mirzadeh, Zaman; Muta, Kenjiro; Scarlett, Jarrad; Brown, Jenny M.; Herranz-Pérez, Vicente; Baquero, Arian F; Thompson, Jonatan; Alonge, Kimberly M.; Faber, Chelsea; Kaiyala, Karl J.; Bennett, Camdin; Pyke, Charles; Ratner, Cecilia; Egerod, Kristoffer Lihme; Kornum, Birgitte R.; García-Verdugo, Jose Manuel; Secher, Anna; Jorgensen, Rasmus; Schwartz, Michael; Pers, Tune Nature Research (2020)
      n rodent models of type 2 diabetes (T2D), sustained remission of hyperglycemia can be induced by a single intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1), and the mediobasal hypothalamus (MBH) ...