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Comprehensive investigation on synthetic cannabinoids: metabolic behaviour, detectability and potency testing, using 5F-APP-PICA and AMBFUBINACA as model compounds.
(Wiley, 2019-09)
Synthetic cannabinoids (SCs) represented 45% of new psychoactive substances seizures in Europe (data from 2016). The consumption of SCs is an issue of concern due to their still unknown toxicity and effects on human health, ...
Pharmaceutical removal from different water matrixes by Fenton process at near-neutral pH: Doehlert design and transformation products identification by UHPLC-QTOF MS using a purpose-built database
(Elsevier, 2018-08)
This work evaluates the Fenton process in the removal of eight pharmaceuticals (gemfibrozil, nimesulide, furosemide, paracetamol, propranolol, dipyrone, fluoxetine, and diazepam), present at an initial concentration of ...
Olive oil quality classification and measurement of its organoleptic attributes by untargeted GC – MS and multivariate statistical-based approach
(Elsevier, 2019-01-15)
The capabilities of dynamic headspace entrainment followed by thermal desorption in combination with gas
chromatography (GC) coupled to single quadrupole mass spectrometry (MS) have been tested for the determi-
nation ...
What about the herb? A new metabolomics approach for synthetic cannabinoid drug testing
(Springer Verlag, 2018-08)
Synthetic cannabinoids (SCs) are consumed as legal alternative to cannabis and often allow passing drug-screening tests. Their rapid transience on the drug scene, combined with their mostly unknown metabolic profiles, ...
Isotope Dilution LC-ESI-MS/MS and low resolution Selected Reaction Monitoring as a tool for the accurate quantification of urinary testosterone
(Elsevier, 2018-09)
A new analytical method for the quantification of testosterone in human urine samples by isotope dilution mass spectrometry is proposed. A standard solution of 13C2-testosterone is added to the samples at the beginning of ...
Re-certification of hydroxyvitamin D standards by isotope pattern deconvolution
(Elsevier, 2019-04-22)
Background
Vitamin D testing in analytical clinical laboratories has been experiencing a rapid increase of demand over the last years, as it plays a key role in several disorders. Due to the narrow ranges of medical ...
Investigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data.
(Wiley, 2018-08-20)
New psychoactive substances (NPS) have increased in use and popularity worldwide. Wastewater analysis has been successfully applied to evaluate illicit drugs use within a population. However, for NPS, such an approach may ...
Metabolism of N-ethylhexedrone and buphedrone: An in vivo study in mice using HPLC-MS/MS
(Elsevier, 2020-08-25)
N-ethylhexedrone (NEH) and buphedrone (BUPH) are synthetic drugs structurally related to natural cathinone. These synthetic cathinones (SC) are members of the heterogenous family of new psychoactive substances (NPS), which ...
Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)
(Elsevier, 2018-02-01)
The pesticide chlorpyrifos-methyl (CLP-m) has been identified in plant ingredients intended for aquaculture feed production. To investigate systemic effects of CLP-m with emphasis on lipid metabolism, post-smolt Atlantic ...
Global Assessment of Seawater Intrusion Problems (Status and Vulnerability)
(Springer Netherlands, 2018)
In this research paper we propose a novel method to perform an integrated analysis of the status and vulnerability of coastal aquifers to seawater intrusion (SWI). The method is based on a conceptual approach of intrusion ...