Engineered Immobilised Organocatalysts for the Synthesis of Chiral Amines
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Other documents of the author: Maciá, María; Muñoz, Iván; Porcar, Raúl; Cirujano, Francisco; Altava, Belen; Luis, Santiago V.; Garcia-Verdugo, Eduardo
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Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
comunitat-uji-handle4:
INVESTIGACIONMetadata
Title
Engineered Immobilised Organocatalysts for the Synthesis of Chiral AminesAuthor (s)
Date
2024-02-20Publisher
WileyISSN
1615-4150; 1615-4169Bibliographic citation
M. Maciá, I. Muñoz, R. Porcar, F. G. Cirujano, B. Altava, S. V. Luis, E. García-Verdugo, Adv. Synth. Catal. 2024, 366, 892. https://doi.org/10.1002/adsc.202301221Type
info:eu-repo/semantics/articlePublisher version
https://onlinelibrary.wiley.com/doi/full/10.1002/adsc.202301221Version
info:eu-repo/semantics/publishedVersionSubject
Abstract
The art of tuning functional polymeric materials through the covalent incorporation of organocatalysts lies at the core of creating asymmetric immobilized chiral catalysts that mimic the enzymatic action. Herein, we ... [+]
The art of tuning functional polymeric materials through the covalent incorporation of organocatalysts lies at the core of creating asymmetric immobilized chiral catalysts that mimic the enzymatic action. Herein, we explore diverse synthetic techniques to immobilize l-proline-derived N-carbonyl amides on functional polymeric matrices, transforming them into chiral Lewis bases for facilitating the asymmetric reduction of ketimines with HSiCl3. A comprehensive examination of the design factors, encompassing linker selection, anions, and polymeric support characteristics, enables precise adjustment of steric and electronic features in these immobilized catalysts. This approach establishes structure-performance relationships, ultimately enabling the development of an engineered immobilized organocatalytic system that meets the desired criteria for activity, stability, and selectivity. [-]
Is part of
Advanced Synthesis & Catalysis, 2024, vol. 366, no 4Funder Name
Universitat Jaume I | Ministerio de Ciencia e Innovación
Funder ID
http://dx.doi.org/10.13039/501100011033
Project code
UJI-B2021-31 | MCIN/PEICTI2021-2023/PID2021-124695OB-C22 | RYC2020-028681-I
Project title or grant
Nuevas Herramientas en Química Verde para el Desarrollo de Procesos (Bio)Catalíticos Sostenibles de Valorización del Co2 y la Obtención Compuestos de Alto Valor Añadido
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info:eu-repo/semantics/openAccess
This item appears in the folowing collection(s)
- QUIO_Articles [702]
Except where otherwise noted, this item's license is described as © 2024 The Authors. Advanced Synthesis & Catalysis published by Wiley-VCH GmbH. This is an open access article under theterms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in anymedium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.