Engineered Immobilised Organocatalysts for the Synthesis of Chiral Amines
Impacte
Scholar |
Altres documents de l'autoria: Maciá, María; Muñoz, Iván; Porcar, Raúl; Cirujano, Francisco; Altava, Belen; Luis, Santiago V.; Garcia-Verdugo, Eduardo
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
comunitat-uji-handle4:
INVESTIGACIONMetadades
Títol
Engineered Immobilised Organocatalysts for the Synthesis of Chiral AminesAutoria
Data de publicació
2024-02-20Editor
WileyISSN
1615-4150; 1615-4169Cita bibliogràfica
M. Maciá, I. Muñoz, R. Porcar, F. G. Cirujano, B. Altava, S. V. Luis, E. García-Verdugo, Adv. Synth. Catal. 2024, 366, 892. https://doi.org/10.1002/adsc.202301221Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
https://onlinelibrary.wiley.com/doi/full/10.1002/adsc.202301221Versió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
The art of tuning functional polymeric materials through the covalent incorporation of organocatalysts lies at the core of creating asymmetric immobilized chiral catalysts that mimic the enzymatic action. Herein, we ... [+]
The art of tuning functional polymeric materials through the covalent incorporation of organocatalysts lies at the core of creating asymmetric immobilized chiral catalysts that mimic the enzymatic action. Herein, we explore diverse synthetic techniques to immobilize l-proline-derived N-carbonyl amides on functional polymeric matrices, transforming them into chiral Lewis bases for facilitating the asymmetric reduction of ketimines with HSiCl3. A comprehensive examination of the design factors, encompassing linker selection, anions, and polymeric support characteristics, enables precise adjustment of steric and electronic features in these immobilized catalysts. This approach establishes structure-performance relationships, ultimately enabling the development of an engineered immobilized organocatalytic system that meets the desired criteria for activity, stability, and selectivity. [-]
Publicat a
Advanced Synthesis & Catalysis, 2024, vol. 366, no 4Entitat finançadora
Universitat Jaume I | Ministerio de Ciencia e Innovación
Identificador de l'entitat finançadora
http://dx.doi.org/10.13039/501100011033
Codi del projecte o subvenció
UJI-B2021-31 | MCIN/PEICTI2021-2023/PID2021-124695OB-C22 | RYC2020-028681-I
Títol del projecte o subvenció
Nuevas Herramientas en Química Verde para el Desarrollo de Procesos (Bio)Catalíticos Sostenibles de Valorización del Co2 y la Obtención Compuestos de Alto Valor Añadido
Drets d'accés
info:eu-repo/semantics/openAccess
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Except where otherwise noted, this item's license is described as © 2024 The Authors. Advanced Synthesis & Catalysis published by Wiley-VCH GmbH. This is an open access article under theterms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in anymedium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.