Synthesis of polyfunctionals pseudopeptidic compounds

Abstract

According to Lehn, "Supramolecular chemistry is the chemistry of intermolecular bonding, which encompasses the structures and functions of entities formed by association of two or more chemical species".1 Supramolecular chemistry studies the phenomena such as molecular self-assembly, protein folding, molecular recognition, host-guest chemistry, mechanically-interlocked molecular architectures, and dynamic covalent chemistry. It is highly interdisciplinary in nature and attracts not just chemists but biologists, environmental scientists, physicists, biochemists, theoreticians, crystallographers.2 Supramolecular system is a self-assembled entity without covalent bonds, in which complete molecular units are joined by non-covalent forces to create a complete structure (as shown in Figure 1). The study of systems that include such structures formed by non-covalent interactions, such as hydrogen bonding, dipole-dipole, van der Waals, charge transfer and π-π interactions, is known as Supramolecular Chemistry.