Cromatography hyphenated to high resolution mass spectrometry in untargeted metabolomics for investigation of food (bio) markers
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Title
Cromatography hyphenated to high resolution mass spectrometry in untargeted metabolomics for investigation of food (bio) markersAuthor (s)
Tutor/Supervisor; University.Department
Portolés Nicolau, Tania; Universitat Jaume I. Departament de Química Física i AnalíticaDate
2020-09-09Publisher
Universitat Jaume IAbstract
Currently, there is a growing demand by our society, authorities and science to increase the
knowledge about the food consumed and its relationship with health and disease. Untargeted
metabolomics approaches are ... [+]
Currently, there is a growing demand by our society, authorities and science to increase the
knowledge about the food consumed and its relationship with health and disease. Untargeted
metabolomics approaches are emerging as powerful tools for exploring metabolic changes in the
biological system under different conditions, and it is known their potential in food studies. In
addition, chromatography hyphenated to high resolution mass spectrometry provides sensitivity
and selectivity enough to cover a wide range of metabolites in complex samples. This work is a
part of a comprehensive study whose aim is to provide an overview of the most widely adopted
method of high resolution mass spectrometry-based techniques for the identification of food
(bio)markers through the untargeted metabolomics workflow. Detailed information is provided
about the new trends in each stage from updated literature from the last three years and other
reviews with the objective of helping researchers to optimize a proper methodology. This
fragment covers study design, sample preparation and data acquisition, including additional
sections of future prospects and applications. [-]
Subject
Màster Universitari en Tècniques Cromatogràfiques Aplicades | Máster Universitario en Técnicas Cromatográficas Aplicadas | University Master's Degree in Applied Chromatographic Techniques | metabolomics | untargeted | fingerprinting | high resolution mass spectrometry | liquid chromatography | gas chromatography | ion mobility spectrometry | food intake | food health | food processing | food authenticity | food quality | food traceability | food safety and biomarkers
Description
Treball de Fi de Màster Universitari en Tècniques Cromatogràfiques Aplicades (Pla de 2013). Codi: SIY009. Curs 2019/2020
Type
info:eu-repo/semantics/masterThesisRights
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info:eu-repo/semantics/restrictedAccess