Mostrar el registro sencillo del ítem
High doses of folic acid in the periconceptional period and risk of low weight for gestational age at birth in a population based cohort study.
dc.contributor.author | Navarrete-Muñoz, Eva María | |
dc.contributor.author | Valera-Gran, Desirée | |
dc.contributor.author | Garcia de la Hera, Manuela | |
dc.contributor.author | González-Palacios, Sandra | |
dc.contributor.author | Riaño-Galan, Isolina | |
dc.contributor.author | Murcia, Mario | |
dc.contributor.author | Lertxundi, Aitana | |
dc.contributor.author | Guxens, Mònica | |
dc.contributor.author | Tardon, Adonina | |
dc.contributor.author | Amiano, Pilar | |
dc.contributor.author | Vrijheid, Martine | |
dc.contributor.author | Rebagliato, Marisa | |
dc.contributor.author | Vioque, Jesus | |
dc.date.accessioned | 2020-03-27T10:37:49Z | |
dc.date.available | 2020-03-27T10:37:49Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | NAVARRETE-MUÑOZ, Eva María;VALERA-GRAN,Desirée; GARCÍA DE LA HERA, Manuela; GONZÁLEZ-PALACIOS, Sandra; RIAÑO-GALAN, Isolina; MURCIA, Mario; LERTXUNDI, Aitana; GUXENS, Mònica; TARDON, Adonina; AMIANO, Pilar; VRIJHEID, Martine; REBAGLIATO, Marisa; VIOQUE, Jesús (2018). High doses of folic acid in the periconceptional period and risk of low weight for gestational age at birth in a population based cohort study. European Journal of Nutrition, v. 58, p. 241-251 | ca_CA |
dc.identifier.uri | http://hdl.handle.net/10234/187167 | |
dc.description.abstract | Purpose We investigated the association between maternal use of folic acid (FA) during pregnancy and child anthropometric measures at birth. Methods We included 2302 mother–child pairs from a population-based birth cohort in Spain (INMA Project). FA dosages at first and third trimester of pregnancy were assessed using a specific battery questionnaire and were categorized in non-user, <1000, 1000–4999, and ≥5000 µg/day. Anthropometric measures at birth (weight in grams, length and head circumference in centimetres) were obtained from medical records. Small for gestational age according to weight (SGA-w), length (SGA-l) and head circumference (SGA-hc) were defined using the 10th percentile based on Spanish standardized growth reference charts. Multiple linear and logistic regression analyses were used to explore the association between FA dosages in different stages of pregnancy and child anthropometric measures at birth. Results In the multiple linear regression analysis, we found a tendency for a negative association between the use of high dosages of FA (≥5000 µg/day) in the periconceptional period of pregnancy and weight at birth compared to mothers who were non-users of FA (β = − 73.83; 95% CI − 151.71, 4.06). In the multiple logistic regression, a greater risk of SGA-w was also evident among children whose mothers took FA dosages of 1000–4999 (OR=2.21; 95% CI 1.17, 4.19) and of ≥5000 µg/ day (OR=2.32; 95% CI 1.06, 5.08) compared to mothers non-users of FA in the periconceptional period of pregnancy. Conclusion Our findings suggest that a high dosage of FA (≥1000 µg/day) may be associated with an increased risk of SGA-w at birth. | ca_CA |
dc.format.extent | 11 p. | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Springer | ca_CA |
dc.relation.isPartOf | European Journal of Nutrition (2019), v. 58 | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.subject | Folate intake | ca_CA |
dc.subject | Folic acid | ca_CA |
dc.subject | Pregnancy | ca_CA |
dc.subject | Small for gestational age according to weight | ca_CA |
dc.subject | Cohort study | ca_CA |
dc.title | High doses of folic acid in the periconceptional period and risk of low weight for gestational age at birth in a population based cohort study. | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | https://doi.org/10.1007/s00394-017-1588-7 | |
dc.relation.projectID | 1) Instituto de Salud Carlos III and Spanish Ministry of Health (Red INMA G03/176; CB06/02/0041; FIS 97/0588; 00/0021-2, PI061756; PS0901958; FIS-FEDER 03/1615, 04/1509, 04/1112, 04/1931, 05/1079, 05/1052, 06/1213, 07/0314; 09/02647; FIS-PI041436, FIS-PI081151, FISPI06/0867; FIS-PS09/00090, FIS-PI042018, FIS-PI09 02311, FIS PI11/01007, FISPI13/02429) ; 2) Generalitat de Catalunya-CIRIT 1999SGR 00241; 3) Department of Health of the Basque Government (2005111093 and 2009111069); 4) Provincial Government of Guipuzcoa (DFG06/004 and DFG08/001). | ca_CA |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.relation.publisherVersion | https://link.springer.com/article/10.1007%2Fs00394-017-1588-7 | ca_CA |
dc.contributor.funder | 1) Universidad de Oviedo; 2) Conselleria de Sanitat Generalitat Valenciana | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
Ficheros en el ítem
Ficheros | Tamaño | Formato | Ver |
---|---|---|---|
No hay ficheros asociados a este ítem. |
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
MED_Articles [667]
Articles de publicacions periòdiques