Photomodulation of DNA‐Templated Supramolecular Assemblies
Impacto
Scholar |
Otros documentos de la autoría: RUBIO-MAGNIETO, JENIFER; Phan, Tuan‐Anh; Fossépré, Mathieu; Matot, Valérie; Knoops, Jérémie; Jarrosson, Thibaut; Dumy, Pascal; Serein‐Spirau, Françoise; Niebel, Claude; Ulrich, Sébastien; Surin, Mathieu
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7053
comunitat-uji-handle3:10234/8639
comunitat-uji-handle4:
INVESTIGACIONEste recurso está restringido
https://doi.org/10.1002/chem.201704538 |
Metadatos
Título
Photomodulation of DNA‐Templated Supramolecular AssembliesAutoría
Fecha de publicación
2018-01-12Editor
WileyISSN
0947-6539; 1521-3765Cita bibliográfica
RUBIO‐MAGNIETO, Jenifer, et al. Photomodulation of DNA‐templated supramolecular assemblies. Chemistry–A European Journal, 2018, vol. 24, no 3, p. 706-714Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201704538Versión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
A new type of DNA ligand that contains a phosphate‐binding group and a photoresponsive azobenzene moiety is reported. When the azobenzene is in trans configuration, the ligand binds to the minor groove of a double‐s ... [+]
A new type of DNA ligand that contains a phosphate‐binding group and a photoresponsive azobenzene moiety is reported. When the azobenzene is in trans configuration, the ligand binds to the minor groove of a double‐stranded DNA, whereas it partially desorbs upon trans–cis isomerisation with light. The ability to photoswitch the ligand upon interaction with DNA is evidenced by (chir)optical signatures, and deciphered by the differences of binding geometry, stability, and dynamics of the DNA/ligand complexes for the two isomers. We exploit these properties to photomodulate DNA‐templated self‐assembly, through the incorporation of another π‐stacking DNA ligand, which together with the photoresponsive ligand form mixed supramolecular complexes along DNA. Our study demonstrates that well‐designed photoresponsive DNA binders can be used to modulate multicomponent supramolecular DNA assemblies. [-]
Publicado en
Chemistry–A European Journal, 2018, vol. 24, no 3Proyecto de investigación
Fonds de la Recherche Scientifique-FNRS: 1.B333.15F, F.4532.16; Science Policy Office of the Belgian Federal Government: BELSPO-PAI 7/5; LabEx CheMISyst: ANR-10-LABX-05-01Derechos de acceso
Copyright © John Wiley & Sons, Inc.
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/restrictedAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/restrictedAccess
Aparece en las colecciones
- QUIO_Articles [705]