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Tuneable 3D printed bioreactors for transaminations under continuous-flow

dc.contributor.authorPeris, Edgar
dc.contributor.authorOkafor, Obinna
dc.contributor.authorKulcinskaja, Evelina
dc.contributor.authorGoodridge, Ruth
dc.contributor.authorLuis, Santiago V.
dc.contributor.authorGarcia-Verdugo, Eduardo
dc.contributor.authorO'Reilly, Elaine
dc.contributor.authorSans, Victor
dc.date.accessioned2018-03-08T12:35:30Z
dc.date.available2018-03-08T12:35:30Z
dc.date.issued2017-11-21
dc.identifier.citationPERIS, Edgar; OKAFOR, Obinna; KULCINSKAJA, Evelina; GOODRIDGE, Ruth; LUIS LAFUENTE, Santiago Vicente; GARCÍA VERDUGO, Eduardo; O'REILLY, Elaine; SANS, Víctor. Tuneable 3D printed bioreactors for transaminations under continuous-flow. Green Chemistry (2017), v. 19, n. 21, p. 5345-5349ca_CA
dc.identifier.urihttp://hdl.handle.net/10234/173237
dc.description.abstractA method to efficiently immobilize enzymes on 3D printed continuous- fl ow devices is presented. Application of these chemically modi fi ed devices enables rapid screening of immobilization mechanisms and reaction conditions, simple transfer of optimised conditions into tailored printed micro fl uidic reactors and development of continuous- fl ow biocatalytic processes. The bioreactors showed good activity (8 – 20.5 μ mol h − 1 mg enz − 1 ) in the kinetic resolution of 1-methylbenzylamine, and very good stability ( ca. 100 h under fl ow).ca_CA
dc.format.extent5 p.ca_CA
dc.language.isoengca_CA
dc.publisherRoyal Society of Chemistryca_CA
dc.relation.isPartOfGreen Chemistry (2017), issue 19, n. 22ca_CA
dc.rights.urihttp://rightsstatements.org/vocab/CNE/1.0/*
dc.subjectEnzymesca_CA
dc.subject3D printed continousca_CA
dc.subjectModified devicesca_CA
dc.subjectReaction conditionsca_CA
dc.subjectContinuous- flow biocatalytic processesca_CA
dc.subjectBioreactorsca_CA
dc.subject1-methylbenzylamineca_CA
dc.titleTuneable 3D printed bioreactors for transaminations under continuous-flowca_CA
dc.typeinfo:eu-repo/semantics/articleca_CA
dc.identifier.doihttp://dx.doi.org/10.1039/c7gc02421e
dc.relation.projectID1) The Royal Society (RG150021) for funding ; 2) The Research Priority Area (RPA) of UoN in Industrial Biotechnology for funding; 3) Funding from the BBSRC (BB/M021947/1); 4) EPSRC (EP/I033335/2); 5) Partially supported by G. V. (PROMETEO 2016-071) and 6) MINECO (CTQ2015-68429R); 7) MICINN for personal financial support (FPU13/00685))ca_CA
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_CA
dc.relation.publisherVersionhttp://pubs.rsc.org/en/content/articlepdf/2017/gc/c7gc02421eca_CA
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_CA


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