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Synthesis of Inhibitors of Cysteine Protease
dc.contributor.author | Escrig Traver, Judith | |
dc.contributor.other | González Adelantado, Florenci Vicent | |
dc.date.accessioned | 2017-12-18T12:12:40Z | |
dc.date.available | 2017-12-18T12:12:40Z | |
dc.date.issued | 2017-07-14 | |
dc.identifier.uri | http://hdl.handle.net/10234/171153 | |
dc.description | Treball Final de Grau en Química. Codi: QU0943 | ca_CA |
dc.description.abstract | Protozoa which cause diseases such as Malaria, Chagas’ disease or Sleeping sickness contains cysteine proteases. These enzymes are important in the cycle life of parasites. Inhibitors of cysteine proteases represent a way to find new drugs against these tropical infectious diseases. Lately, several inhibitors for this type of proteases were developed. In this work, a dipeptidyl nitrolkene has been synthetized, with a new modification in the chemical structure: isonicotinyl as a protecting group. This compound is expected to display a high inhibition activity against cysteine proteases. | ca_CA |
dc.format.extent | 56 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | Universitat Jaume I | ca_CA |
dc.rights.uri | http://rightsstatements.org/vocab/CNE/1.0/ | * |
dc.subject | Grau en Química | ca_CA |
dc.subject | Grado en Química | ca_CA |
dc.subject | Bachelor's Degree in Chemistry | ca_CA |
dc.subject | Inhibitor | ca_CA |
dc.subject | Nitroalkenes | ca_CA |
dc.subject | Cysteine proteases | ca_CA |
dc.subject | Trypanosoma cruzi | ca_CA |
dc.subject | Trypanosoma brucei | ca_CA |
dc.subject | Malaria | ca_CA |
dc.subject | Chagas’ disease | ca_CA |
dc.subject | Sleeping sickness | ca_CA |
dc.title | Synthesis of Inhibitors of Cysteine Protease | ca_CA |
dc.type | info:eu-repo/semantics/bachelorThesis | ca_CA |
dc.educationLevel | Estudios de Grado | ca_CA |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_CA |
dc.audience.educationlevel | Universitat Jaume I. Departament de de Química Inorgànica i Orgànica |
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