Synthesis of Inhibitors of Cysteine Protease
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Synthesis of Inhibitors of Cysteine ProteaseAutoria
Tutor/Supervisor; Universitat.Departament
González Adelantado, Florenci VicentData de publicació
2017-07-14Editor
Universitat Jaume IResum
Protozoa which cause diseases such as Malaria, Chagas’ disease or Sleeping sickness contains cysteine proteases. These enzymes are important in the cycle life of parasites. Inhibitors of cysteine proteases represent ... [+]
Protozoa which cause diseases such as Malaria, Chagas’ disease or Sleeping sickness contains cysteine proteases. These enzymes are important in the cycle life of parasites. Inhibitors of cysteine proteases represent a way to find new drugs against these tropical infectious diseases.
Lately, several inhibitors for this type of proteases were developed. In this work, a dipeptidyl nitrolkene has been synthetized, with a new modification in the chemical structure: isonicotinyl as a protecting group. This compound is expected to display a high inhibition activity against cysteine proteases. [-]
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Descripció
Treball Final de Grau en Química. Codi: QU0943
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info:eu-repo/semantics/bachelorThesisDrets d'accés
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/restrictedAccess
info:eu-repo/semantics/restrictedAccess
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- Grau en Química [265]