ListarPrograma de Doctorat en Ciències por tema "615"
Mostrando ítems 1-7 de 7
-
Anàlisi de fàrmacs prescrits en tractaments de SIDA en plasma i sèrum mitjançant cromatografia líquida micel·lar
Universitat Jaume I (2015-05-29)En la present memòria es presenten diferents estratègies analítiques basades en MLC per a la determinació de antirretrovirals i antivirals usats en la terapia HAART (prescrita contra la SIDA) en mostres de plasma i sèrum. ... -
Application of advanced mass spectrometric techniques for the identification, metabolic characterisation and toxicological analysis of new psychoactive substances
Universitat Jaume I (2020-11-27)This Doctoral Thesis presents an in-depth investigation on NPS from the analytical chemistry point of view, being structured in three blocks. The first is focused on the analytical characterisation of different compounds, ... -
Degradation of perineuronal nets in the cerebellum to prevent relapse of drug seeking
Universitat Jaume I (2023-03-03)Drug addiction can be associated with the ability of certain substances to hijack natural learning and memory mechanisms. This thesis focuses on the study and manipulation of cerebellar perineuronal nets (PNNs) following ... -
Study of the possible migration risks of food contact materials for children under 3 years
Universitat Jaume I (2016-11-01)El Bisfenol-A (BPA) se ha usado durante muchos años como monómero en polímeros de policarbonato (PC) (botellas de agua y comida para niños-biberones) y en resinas tipo epoxi (botes de comida preparada), a partir de los ... -
Synthesis of combretastatin analogues with antineoplastic properties
Universitat Jaume I (2019-06-25)This doctoral thesis belongs to the field of medicinal and pharmacological chemistry. Its aim is the synthesis, characterization and biological evaluation of three families of aminocombretastatin derivatives, compound with ... -
Synthesis of compounds with potential biomedical activity: SARS-CoV-2 main protease inhibitors and ABA analogs
Universitat Jaume I (2024-04-17)The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has increased the development of new antiviral drugs to stop its spread. This work focused on synthesizing specific inhibitors of the Mpro protease, crucial for the ... -
Synthesis of highly functional polypeptides and polypeptoids via N-carboxyanhydride ring opening polymerization as drug delivery nanosystems
Universitat Jaume I (2024-02-15)In this work, N-carboxyanydride ring opening polymerization (NCA-ROP) has been widely explored and used as synthetic strategy for the synthesis of polypeptides and polypeptoids affording well-defined polymers with low ...