Optimització del diagnòstic microbiològic de la bacterièmia en un hospital sense atenció continuada. Aplicació d’una PCR Multiplex sobre frasc d’hemocultiu
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/29747
comunitat-uji-handle3:10234/162743
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TESISMetadatos
Título
Optimització del diagnòstic microbiològic de la bacterièmia en un hospital sense atenció continuada. Aplicació d’una PCR Multiplex sobre frasc d’hemocultiuAutoría
Director/a
Moreno Muñoz, RosarioPrograma de Doctorado
Programa de Doctorat en Ciències de la InfermeriaÓrgano responsable
Universitat Jaume I. Escola de DoctoratFecha de defensa
2022-06-22Editor
Universitat Jaume IPalabras clave
Diagnòstic | Bacterièmia | Sèpsia | Molecular | Microbiologia | Atenció continuada | Diagnosis | Bacteraemia | Sepsis | Microbiology
Área de conocimiento
Páginas
131 p.;Resumen
The microbiological diagnosis of bacteremia is essential to an early establishment of the approppriate treatment. We present a study of 133 patients performing multiplex PCR (FA-BCID) in parallel with conventional ... [+]
The microbiological diagnosis of bacteremia is essential to an early establishment of the approppriate treatment. We present a study of 133 patients performing multiplex PCR (FA-BCID) in parallel with conventional blood culture. The diagnosis was advanced by about two days on positive blood culture. The concordance was 79%, 95% CI (66.86), due to the detection of S.pneumoniae which was not isolated. In 22% of patients, the ATB was modified when the PCR result was known. The percentage of polymorphonuclear cells and the age are the only relevant parameters in order to condition a positive PCR result. Experimental PCR was performed in non-positivized blood cultures. In six cases the identification could be considerably advanced. The concordance when PCR was negative with the culture was 82.3%. Especially in hospitals without continuous care, FA-BCID is a good tool that can speed up the diagnosis but cannot replace traditional blood culture. [-]
Derechos de acceso
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info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess