Listar QUIO_Articles por fecha de publicación
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Tetrazole derivatives as potent immunomodulatory agents in tumor microenvironment
Elsevier (2023-11-01)Twenty-seven compounds bearing a tetrazole ring as a central unit have been designed, synthetized and biologically evaluated. Studies have been performed in order to compare the effect of tetrazole derivatives bearing amine ... -
Sustainable inorganic pigments with high near-infra-red reflectance based on Fe3+ doped YAlO3 for high temperature applications
Elsevier (2023-10-15)Non-toxic inorganic pigments based on the Fe(III)-doped YAlO3 with high near-infra-red (NIR) reflectance were synthesized by a modified Pechini method at 1200 °C. A complete solid solution in the YAl1−xFexO3 system (0 ≤x ... -
Tools and new metric (Macrocyclization Environmental Impact - MEI) to tackle the sustainability of macrocyclization reactions
Elsevier (2023-10-06)Albeit the numerous scientific advantages provided by macrocyclic compounds, there is still a significant gap between the “proof of concept” research and their application. This is a direct consequence of the challenging ... -
Tuning Ni-Pyrazolate Frameworks by Post-Synthetic Fe-Incorporation for Oxidase-Mimicking H2O2 Activation
Wiley (2023-10-04)The introduction of iron ionic sites by metal exchange of defective homometallic nickel pyrazolate frameworks generates non-precious, Earth-abundant, first-row heterometallic Fe/Ni-pyrazolate frameworks. The Fe incorporation ... -
Impact of the Warhead of Dipeptidyl Keto Michael Acceptors on the Inhibition Mechanism of Cysteine Protease Cathepsin L
American Chemical Society (2023-10-03)Cathepsin L (CatL) is a lysosomal cysteine protease whose activity has been related to several human pathologies. However, although preclinical trials using CatL inhibitors were promising, clinical trials have been ... -
Effect of Hyaluronic Acid on the Self-Assembly of a Dipeptide-Based Supramolecular Gel
Wiley (2023-10-02)The combination of polymers and low molecular weight (LMW) compounds is a powerful approach to prepare new supramolecular materials. Here we prepare two-component hydrogels made by a well-known and biologically active ... -
Intracellular Zn(ii) induced turn-on fluorescence of an l-phenylalanine-derived pseudopeptide
Royal Society of Chemistry (2023-10)A C2 symmetric L-phenylalanine-derived pseudopeptide has been synthesized for selective and sensitive recognition of Zn(II) ions in aqueous–organic media. The pseudopeptidic probes exhibit intracellular Zn(II) ion-sensing ... -
Structural and electrical properties of Zr-doped K0.48Na0.52NbO3 ceramics: “Hard” lead-free piezoelectric
Elsevier (2023-10)The structural and electrical properties of K0.48Na0.52Nb1−xZrxO3−δ (x = 0–0.04) ceramics prepared by the conventional solid-state reaction method were studied. Pellets with composition x ≤ 0.03 sintered at 1125 °C for 2 ... -
Kinetics or thermodynamics? Extolling their role to modulate the crystal phases and luminescence of KY3F10:Eu3+ powders
Royal Society of Chemistry (2023-09-28)KY3F10, a fluoride compound with two polymorphs (alpha and delta), has been a subject of study due to its unique properties. Obtaining the metastable delta-phase has been challenging, but this study presents an enhanced ... -
Concurso de cristalización en la escuela: una herramienta educativa innovadora
Infoedita (2023-09-01) -
Novel electrolytes based on mixtures of dimethyl sulfoxide task specific zwitterionic ionic liquid and lithium salts: Synthesis and conductivity studies
Elsevier (2023-08-09)Novel methyl sulfoxide imidazolium-based zwitterionic low melting salts was synthesized and characterized. The combination of this functionalized zwitterion and lithium bis(trifluoromethylsulfonyl)amide (LiNTf2) salts at ... -
Functional properties of transparent ZnO thin films synthetized by using spray pyrolysis for environmental and biomedical applications
Elsevier (2023-08-02)Spray pyrolysis is a promising method for producing thin, transparent films on glass substrates. ZnO thin films synthesized by this method exhibit high crystallinity, adhesion and chemical resistance. They also possess the ... -
Direct Air Capture and Integrated Conversion of Carbon Dioxide into Cyclic Carbonates with Basic Organic Salts
American Chemical Society (2023-07-03)Direct air capture and integrated conversion is a very attractive strategy to reduce CO2 concentration in the atmosphere. However, the existing capturing processes are technologically challenging due to the costs of the ... -
Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies
MDPI (2023-05-11)Thirteen benzylethoxyaryl ureas have been synthesized and biologically evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins to overcome resistance phenomena offered by cancer. The antiproliferative activity ... -
Impact of the Recognition Part of Dipeptidyl Nitroalkene Compounds on the Inhibition Mechanism of Cysteine Proteases Cruzain and Cathepsin L
American Chemical Society (2023-05-05)Cysteine proteases (CPs) are an important class of enzymes, many of which are responsible for several human diseases. For instance, cruzain of protozoan parasite Trypanosoma cruzi is responsible for the Chagas disease, ... -
A site-selective fluorescence spectroscopy study of the crystal phases of KY3F10: Leveraging the optical response of Eu3+ ions
Elsevier (2023-04-18)The present work deals with the investigation of the site-selective symmetries in Eu3+-doped KY3F10 with different crystal phases. Employing time-resolved fluorescence line-narrowing (TRFLN), a study of the luminescent ... -
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive Reactivity and Selectivity Study
MDPI (2023-04-13): Covalent peptidomimetic protease inhibitors have gained a lot of attention in drug development in recent years. They are designed to covalently bind the catalytically active amino acids through electrophilic groups ... -
On the role of multifunctional ionic liquids for the oxidative carboxylation of olefins with carbon dioxide
Elsevier (2023-03-23)Ionic liquids (ILs) are catalysts with profound effects on the activity and selectivity for the transformation of CO2. In particular, highly functionalisable and immobilisable imidazolium based ILs (ImILs) activate CO2 ... -
Gold nanoparticle-based two-photon fluorescent nanoprobe for monitoring intracellular nitric oxide levels
Royal Society of Chemistry (2023-03-08)Nitric oxide (NO) plays an important role in the regulation of the immune, cardiovascular and nervous systems. Consequently, being able to monitor and quantify intracellular NO levels would provide a greater understanding ... -
Evaluation of Pr2Zr2−xCexO7±δ pyrochlores as a potential Cu support catalysts for CO oxidation in simulated GDI conditions
Elsevier (2023-03)This study evaluates the catalytic activity, both as bulk catalysts and as supports for copper catalysts for CO oxidation in a simulated Gasoline Direct Injection Engine (GDI) of two pyrochlores: Pr2Zr2O7 (PZ) and ...