Listar QUIO_Articles por autoría "e3411002-4c83-4035-b535-bedb0367c2d9"
Mostrando ítems 1-9 de 9
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A bioinspired approach toward efficient supramolecular catalysts for CO2 conversion
Esteve Franch, Ferran; Porcar Garcia, Raul; Bolte, Michael; Altava, Belen; Luis, Santiago V.; Garcia-Verdugo, Eduardo Elsevier (2022-12-21)Nature uses enzymes for affording astonishingly efficient chemical transformations with high chemo-, regio-, and stereoselectivity (e.g., carbonic anhydrase for CO2 conversion). Such sophisticated biomolecules lead to ... -
Basically, nucleophilicity matters little: towards unravelling the supramolecular driving forces in enzyme-like CO2 conversion
Esteve Franch, Ferran; Altava, Belen; Luis, Santiago V.; Garcia-Verdugo, Eduardo Royal Society of Chemistry (2022-08-03)The reaction mechanism for the cycloaddition of CO2 to styrene oxide in the presence of macrocyclic pseudopeptides has been studied using DFT methods. Computational calculations indicate that the unprecedented catalytic ... -
Continuous Flow Processes as an Enabling Tool for the Synthesis of Constrained Pseudopeptidic Macrocycles
Esteve Franch, Ferran; Porcar Garcia, Raul; Luis, Santiago V.; Altava, Belen; Garcia-Verdugo, Eduardo American Chemical Society (2022-02-15)Herein we report our efforts to develop a continuous flow methodology for the efficient preparation of pseudopeptidic macrocyclic compounds containing the hexahydropyrrolo-[3,4-f]-isoindolocyclophane scaffold and involving ... -
Doubly chiral pseudopeptidic macrobicyclic molecular cages: Water-assisted dynamic covalent self-assembly and chiral self-sorting
Esteve Franch, Ferran; Altava, Belen; Garcia-Verdugo, Eduardo; Luis, Santiago V.; Lehn, Jean-Marie Elsevier (2022-06-27)Taking advantage of the dynamic covalent chemistry approach, four different cages were synthesized by condensation of tripodal pseudopeptides with 4,4′-biphenyldicarboxyaldehyde. Whereas undesired products of polymeric ... -
Highly Selective Anion Template Effect in the Synthesis of Constrained Pseudopeptidic Macrocyclic Cyclophanes
Esteve Franch, Ferran; Altava, Belen; Bolte, Michael; Burguete, M. Isabel; Garcia-Verdugo, Eduardo; Luis, Santiago V. American Chemical Society (2019-12-20)Herein, we report the synthesis of a novel family of constrained pseudopeptidic macrocyclic compounds containing the hexahydropyrrolo[3,4-f]isoindolocyclophane scaffold and involving four coupled substitution reactions in ... -
Immobilized Supramolecular Systems as Efficient Synzymes for CO2 Activation and Conversion
Esteve Franch, Ferran; Escrig, Adrian; Porcar Garcia, Raul; Luis, Santiago V.; Altava, Belen; Garcia-Verdugo, Eduardo Wiley (2022-03)Supramolecular catalysis can provide distinct advantages for the catalytic conversion of CO2 into carbonates by cycloaddition to epoxides. For example, the absence of metals in the catalytic site, and the easy design for ... -
Pseudopeptidic Macrocycles as Cooperative Minimalistic Synzyme Systems for the Remarkable Activation and Conversion of CO2 in the Presence of Chloride Anion
Esteve Franch, Ferran; Altava, Belen; Burguete, M. Isabel; Bolte, Michael; Garcia-Verdugo, Eduardo; Luis, Santiago V. Royal Society of Chemistry (2020-06-30)A series of pseudopeptidic compounds have been assayed as organocatalyts for the conversion of CO2 into organic car-bonates through a cooperative multifunctional mechanism. Conformationally constrained pseudopeptidic ... -
Tools and new metric (Macrocyclization Environmental Impact - MEI) to tackle the sustainability of macrocyclization reactions
Esteve Franch, Ferran; Altava, Belen; Luis, Santiago V.; Garcia-Verdugo, Eduardo Elsevier (2023-10-06)Albeit the numerous scientific advantages provided by macrocyclic compounds, there is still a significant gap between the “proof of concept” research and their application. This is a direct consequence of the challenging ... -
Unravelling the Supramolecular Driving Forces in the Formation of CO2-Responsive Pseudopeptidic Low-Molecular-Weight Hydrogelators
Esteve Franch, Ferran; Villanueva Antoli, Alexis; Altava, Belen; Garcia-Verdugo, Eduardo; Luis, Santiago V. MDPI (2022): A new family of C2 -symmetric pseudopeptides with a high functional density for supramolecular interactions has been synthetized through the attachment of four amino acid subunits to a diamino aliphatic spacer. The ...