• openAccess   Aryl urea based scaffolds for multitarget drug discovery in anticancer immunotherapies 

      Martín Beltrán, Celia; Gil-Edo, Raquel; Hernández Ribelles, Germán; Agut, Raúl; Marí Mezquita, Pilar; Carda, Miguel; Falomir, Eva MDPI (2021-04-06)
      Twenty-one styryl and phenethyl aryl ureas have been synthetized and biologically evaluated as multitarget inhibitors of Vascular endothelial growth factor receptor-2 VEGFR-2 and programmed death-ligand-1 (PD-L1) proteins ...
    • openAccess   Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies 

      Gil-Edo, Raquel; Hernández Ribelles, Germán; Royo, Santiago; Thawait, Natasha; Serrels, Alan; Carda, Miguel; Falomir, Eva MDPI (2023-05-11)
      Thirteen benzylethoxyaryl ureas have been synthesized and biologically evaluated as multitarget inhibitors of VEGFR-2 and PD-L1 proteins to overcome resistance phenomena offered by cancer. The antiproliferative activity ...