Listar QUIO_Articles por autoría "641775e8-fe89-4dae-9e92-c01e82958b9e"

Mostrando ítems 1-5 de 5

    • openAccess   Advances in the Development of SARS-CoV-2 Mpro Inhibitors 

      Agost Beltrán, Laura; de la hoz rodriguez, Sergio; Bou Iserte, Lledó; Rodríguez, Santiago; Fernández de la Pradilla Ibáñez, Adrián; González, Florenci MDPI (2022-04-14)
      Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find inhibitors of the main protease (Mpro) of the virus SARS-CoV-2. Initially, previously reported inhibitors of related ...

    • closedAccess   Design, Synthesis and Evaluation of Fluorescent Analogues of Abscisic Acid 

      González, Florenci; Bou Iserte, Lledó; Miguel-López, Borja; de la hoz rodriguez, Sergio; Kersten, Christian; Sánchez-Sarasúa, Sandra; Espinosa-Fernández, Verónica; Sánchez-Pérez, Ana María Wiley (2020-07-13)
      A fluorescent analogue of abscisic acid has been prepared by combining (S)‐abscisic acid (ABA) with nitrobenzoxadiazole (NBD) fluorophore using ethanol amine as a linker. Isomerization of the double bond at the side chain ...

    • closedAccess   Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain 

      Latorre, Antonio; Schirmeister, Tanja; Kesselring, Jochen; Jung, Sascha; Johé, Patrick; Hellmich, Ute A.; Heilos, Anna; Engels, Bernd; Krauth-Siegel, R. Luise; Dirdjaja, Natalie; Bou Iserte, Lledó; Rodríguez, Santiago; González, Florenci American Chemical Society (2016)
      Dipeptidyl nitroalkenes are potent reversible inhibitors of cysteine proteases. Inhibitor 11 resulted to be the most potent one with Ki values of 0.49 and 0.44 nM against rhodesain and cruzain, respectively. According to ...

    • openAccess   Monitoring psychoactive substance use at six European festivals through wastewater and pooled urine analysis 

      Bijlsma, Lubertus; Celma, Alberto; Castiglioni, Sara; Salgueiro-González, Noelia; Bou Iserte, Lledó; Baz Lomba, Jose Antonio; Reid, Malcolm; Dias, M.J.; Lopes, Alvaro; Matias, Joao Luis; Pastor Alcañiz, Laura; Radonic, J.; Turk Sekulic, M.; Shine, Trevor; van Nuijs, Alexander; Hernandez, Felix; Zuccato, Ettore Elsevier (2020-07-10)
      The consumption of psychoactive substances is considered a growing problem in many communities. Moreover, new psychoactive substances (NPS) designed as (legal) substitutes to traditional illicit drugs are relatively easily ...

    • openAccess   Three-Step Telescoped Synthesis of Monosubstituted Vicinal Diamines from Aldehydes 

      Bou Iserte, Lledó; Latorre, Antonio; Rodríguez, Santiago; González, Florenci (2019)
      Aldehydes are easily transformed into vicinal diamines and piperazines through a one-pot procedure including a Darzens reaction and treatment with an amine or diamine and then with a reducing agent. Additionally, quinoxalines ...