ListarPSB_Articles por tema "H2O2"
Mostrando ítems 1-4 de 4
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Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the H2O2 scavenger alpha lipoic acid
Springer (2012)Rationale Hydrogen peroxide (H2 O2) is the co-substrate used by catalase to metabolize ethanol to acetaldehyde in the brain. This centrally formed acetaldehyde has been involved in several ethanol-related behaviors. ... -
Alpha-lipoic acid, a scavenging agent for H2O2, reduces ethanol-stimulated locomotion in mice
Springer-Verlag (2011-07-19)Rationale The main system of central ethanol oxidation is mediated by the enzyme catalase. By reacting with H2O2, brain catalase forms compound I (the catalase–H2O2 system), which is able to oxidize ethanol to acetaldehyde ... -
Reduction in Central H2O2 Levels Prevents Voluntary Ethanol Intake in Mice: A Role for the Brain Catalase- H2O2 System in Alcohol Binge Drinking
Wiley (2014-01)Background: Hydrogen peroxide (H2O2) is the cosubstrate used by the enzyme catalase to form Compound I (the catalase-H2O2 system), which is the major pathway for the conversion of ethanol (EtOH) into acetaldehyde in the ... -
The H2O2 scavenger ebselen decreases ethanol-induced locomotor stimulation in mice
Elsevier (2012)Background In the brain, the enzyme catalase by reacting with H2O2 forms Compound I (catalase–H2O2 system), which is the main system of central ethanol metabolism to acetaldehyde. Previous research has demonstrated that ...