Listar PSB_Articles por autoría "485ce498-939c-4526-8beb-54b89d7680bc"
Mostrando ítems 1-4 de 4
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A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions
Kouhnavardi, Shima; Ecevitoglu, Alev; Dragačević, Vladimir; Sanna, Fabrizio; Arias-Sandoval, Edgar; Kalaba, Predrag; Kirchhofer, Michael; Lubec, Jana; Niello, Marco; Holy, Marion; Zehl, Martin; Pillwein, Matthias; Wackerlig, Judith; Murau, Rita; Mohrmann, Andrea; Beard, Kathryn R.; Sitte, Harald; Urban, Ernst; Sagheddu, Claudia; Pistis, Marco; Plasenzotti, Roberto; Salamone, John; Langer, Thierry; Lubec, Gert; Monje, Francisco J. MDPI (2022-07)Dopamine (DA), the most abundant human brain catecholaminergic neurotransmitter, modulates key behavioral and neurological processes in young and senescent brains, including motricity, sleep, attention, emotion, learning ... -
Behavioral and dopamine transporter binding properties of the modafinil analog (S, S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding
Rotolo, Renee; Kalaba, Predrag; Dragacevic, Vladimir; Presby, Rose; Neri, Julia; Robertson, Emily; Yang, Jen-Hau; Correa, Merce; Bakulev, Vasiliy; Volkova, Natalia N.; Pifl, Christian; Lubec, Gert; Salamone, John Springer (2020)Rationale Atypical dopamine (DA) transport blockers such as modafinil and its analogs may be useful for treating motivational symptoms of depression and other disorders. Previous research has shown that the DA depleting ... -
Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat
Lubec, Jana; Hussein, Ahmed M.; Kalaba, Predrag; Feyissa, Daniel Daba; Arias-Sandoval, Edgar; Cybulska-Klosowicz, Anita; Bezu, Mekite; Stojanovic, Tamara; Korz, Volker; Malikovic, Jovana; Aher, Nilima Y.; Zehl, Martin; Dragačević, Vladimir; Leban, Johann Jakob; Sagheddu, Claudia; Wackerlig, Judith; Pistis, Marco; Correa, Merce; Langer, Thierry; Urban, Ernst; Höger, Harald; Lubec, Gert MDPI (2023-03)The worldwide increase in cognitive decline, both in aging and with psychiatric disorders, warrants a search for pharmacological treatment. Although dopaminergic treatment approaches represent a major step forward, current ... -
The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding
Rotolo, Renee; Dragacevic, Vladimir; Kalaba, Predrag; Urban, Ernst; Zehl, Martin; Roller, Alexander; Wackerlig, Judith; Langer, Thierry; Pistis, Marco; De Luca, Maria Antonietta; Caria, Francesca; Schwartz, Rebecca; Presby, Rose; Yang, Jen-Hau; Samels, Shanna; Correa, Merce; Lubec, Gert; Salamone, John Frontiers Media (2019-06-28)Animal studies of effort-based choice behavior are being used to model effort-related motivational dysfunctions in humans. With these procedures, animals are offered a choice between high-effort instrumental actions ...