Underlying differences in resting-state activity metrics related to sensitivity to punishment
Impacte
Scholar |
Altres documents de l'autoria: Adrián-Ventura, Jesús; Fabregat Nabás, Jaime; Costumero, Víctor; Avila, Cesar
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/8033
comunitat-uji-handle3:10234/8636
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https://doi.org/10.1016/j.bbr.2022.114152 |
Metadades
Títol
Underlying differences in resting-state activity metrics related to sensitivity to punishmentData de publicació
2023-02-02Editor
ElsevierISSN
0166-4328Cita bibliogràfica
Adrián-Ventura J, Fabregat-Nabás J, Costumero V, Ávila C. Underlying differences in resting-state activity metrics related to sensitivity to punishment. Behavioural Brain Research. 2023; 437: 114152. DOI: 10.1016/j.bbr.2022.114152Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
https://www.sciencedirect.com/science/article/pii/S016643282200420XVersió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
Reinforcement sensitivity theory (RST) of personality establishes the punishment sensitivity trait as a source of variation in defensive avoidance/approach behaviors. These individual differences reflect dissimilar ... [+]
Reinforcement sensitivity theory (RST) of personality establishes the punishment sensitivity trait as a source of variation in defensive avoidance/approach behaviors. These individual differences reflect dissimilar sensitivity and reactivity of the fight-flight-freeze and behavioral inhibition systems (FFFS/BIS). The sensitivity to punishment (SP) scale has been widely used in personality research aimed at studying the activity of these systems. Structural and functional neuroimaging studies have confirmed the core biological correlates of FFFS/BIS in humans. Nonetheless, some brain functional features derived from resting-state blood-oxygen level-dependent (BOLD) activity and its association with the punishment sensitivity dimension remain unclear. This relationship would shed light on stable neural activity patterns linked to anxiety-like behaviors and anxiety predisposition. In this study, we analyzed functional activity metrics “at rest” [e.g., regional homogeneity (ReHo) and fractional amplitude of low-frequency fluctuation (fALFF)] and their relationship with SP in key FFFS/BIS regions (e.g., amygdala, hippocampus, and periaqueductal gray) in a sample of 127 healthy adults. Our results revealed a significant negative correlation between the fALFF within all these regions and the scores on SP. Our findings suggest aberrant neural activity (lower fALFF) within the brain’s defense system in participants with high trait anxiety, which in turn could reflect lower FFFS/BIS activation thresholds. These neurally-located differences could lead to pathological fear/anxiety behaviors arising from the FFFS and BIS. [-]
Publicat a
Behavioural brain research, 2023, vol. 437Entitat finançadora
Generalitat Valenciana | Universitat Jaume I | Ministerio de Ciencia, Innovación y Universidades | Ministerio de Educación, Cultura y Deporte
Identificador de l'entitat finançadora
http://dx.doi.org/10.13039/501100011033
Codi del projecte o subvenció
PROMETEO/2020/032 | UJI-B2021–11 | UJI-B2018–22 | MICIU/ICTI2017-2020/PID2019–105077RJ-I00 | FPU15/00825
Títol del projecte o subvenció
Procesamiento afectivo en segundas lenguas: bases biológicas y factores moduladores
Drets d'accés
Copyright © Elsevier B.V.
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info:eu-repo/semantics/restrictedAccess
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/restrictedAccess
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