SiO2-Ag Composite as a Highly Virucidal Material: A Roadmap that Rapidly Eliminates SARS-CoV-2
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Otros documentos de la autoría: Assis, Marcelo de; pagotto simoes, luiz gustavo; Tremiliosi, Guilherme; Coelho, Dyovani; Minozzi, Daniel; Santos, Renato; Vilela, Daiane C. B.; Rodrigues do Santos, Jeziel; Ribeiro , Lara Kelly; Rosa, Ieda; Mascaro, Lucia; Andres, Juan; Longo, Elson
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INVESTIGACIONMetadatos
Título
SiO2-Ag Composite as a Highly Virucidal Material: A Roadmap that Rapidly Eliminates SARS-CoV-2Autoría
Fecha de publicación
2021-03-04Editor
MDPIISSN
2079-4991Cita bibliográfica
Assis, M., Simoes, L. G. P., Tremiliosi, G. C., Coelho, D., Minozzi, D. T., Santos, R. I., … Longo, E. (2021). SiO2-Ag Composite as a Highly Virucidal Material: A Roadmap that Rapidly Eliminates SARS-CoV-2. Nanomaterials, 11(3), 638. doi:10.3390/nano11030638Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://www.mdpi.com/2079-4991/11/3/638/htmVersión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
COVID-19, as the cause of a global pandemic, has resulted in lockdowns all over the world since early 2020. Both theoretical and experimental efforts are being made to find an effective treatment to suppress the virus, ... [+]
COVID-19, as the cause of a global pandemic, has resulted in lockdowns all over the world since early 2020. Both theoretical and experimental efforts are being made to find an effective treatment to suppress the virus, constituting the forefront of current global safety concerns and a significant burden on global economies. The development of innovative materials able to prevent the transmission, spread, and entry of COVID-19 pathogens into the human body is currently in the spotlight. The synthesis of these materials is, therefore, gaining momentum, as methods providing nontoxic and environmentally friendly procedures are in high demand. Here, a highly virucidal material constructed from SiO2-Ag composite immobilized in a polymeric matrix (ethyl vinyl acetate) is presented. The experimental results indicated that the as-fabricated samples exhibited high antibacterial activity towards Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) as well as towards SARS-CoV-2. Based on the present results and radical scavenger experiments, we propose a possible mechanism to explain the enhancement of the biocidal activity. In the presence of O2 and H2O, the plasmon-assisted surface mechanism is the major reaction channel generating reactive oxygen species (ROS). We believe that the present strategy based on the plasmonic effect would be a significant contribution to the design and preparation of efficient biocidal materials. This fundamental research is a precedent for the design and application of adequate technology to the next-generation of antiviral surfaces to combat SARS-CoV-2. [-]
Publicado en
Nanomaterials 2021, 11Entidad financiadora
Fundação de Amparo à Pesquisa do Estado de São Paulo—FAPESP | Conselho Nacional de Desenvolvimento Cientifico e Tecnológico—CNPq | Universitat Jaume I | Ministerio de Ciencia, Innovación y Universidades
Código del proyecto o subvención
FAPESP CEPID/2013/07296-2 | FAPESP/SHELL/2017/11986-5 | PIPE/15/50113-3 - 11/51084-4 | CNPq/ 166281/2017-4 | UJI-B2019-30 | MICI/PGC2018094417-B-I00
Derechos de acceso
info:eu-repo/semantics/openAccess
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