Monitoring new psychoactive substances use through wastewater analysis: current situation, challenges and limitations
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Otros documentos de la autoría: Bijlsma, Lubertus; Celma, Alberto; Lopez, Francisco; Hernandez, Felix
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Título
Monitoring new psychoactive substances use through wastewater analysis: current situation, challenges and limitationsFecha de publicación
2019-06Editor
ElsevierISSN
2468-5844Cita bibliográfica
BIJLSMA, L., et al. Monitoring New Psychoactive Substances use through wastewater analysis: current situation, challenges and limitations. Current Opinion in Environmental Science & Health, 2019, vol. 9, p. 1-12Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://www.sciencedirect.com/science/article/pii/S2468584418301181Versión
info:eu-repo/semantics/submittedVersionPalabras clave / Materias
Resumen
New psychoactive substances (NPSs) are compounds that produce similar effects to those induced by illicit drugs (IDs), such as cocaine, cannabis, and amphetamines, but are not strictly regulated by international ... [+]
New psychoactive substances (NPSs) are compounds that produce similar effects to those induced by illicit drugs (IDs), such as cocaine, cannabis, and amphetamines, but are not strictly regulated by international conventions. The consumption of NPSs is a growing public health problem in many communities. However, there is little knowledge regarding the extent and actual use of these new substances. Monitoring NPS use is arduous, and therefore, different sources of information need to be used to get more insight of the prevalence and diffusion of NPS use. Analysis of pooled urine and wastewater (WW) shows strong potential, giving a different and complementary light on this issue, although presents some limitations and challenges that must be taken into account. Liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) is one of the most powerful approaches for screening a large number of NPSs because of the accurate-mass full-spectrum acquisition measurements. By using a comprehensive and updated NPS database, LC-HRMS is flexible enough to confront the ever-changing NPS market. In this “current opinion”, we give our point of view on the usefulness of pooled urine and WW analysis and on the potential application of wastewater-based epidemiology as source of information for NPS use, explaining the main bottlenecks and future perspectives in this emerging research field. [-]
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Current Opinion in Environmental Science & Health, 2019, vol. 9Proyecto de investigación
Spanish Ministry of Economy and Competitiveness: Project: CTQ2015-65603-P; Ministry of Economy and Competitiveness of Spain for his predoctoral grant: BES-2016-076914)Derechos de acceso
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